scholarly journals APOB Gene

2020 ◽  
Author(s):  
Keyword(s):  
Apob Gene

In vitro characterization revealed five new potential pathogenic variants in the APOB gene

2021 ◽  
Vol 331 ◽  
pp. e183-e184
Author(s):  
M.D. Di Taranto ◽  
U. Galicia ◽  
A. Larrea ◽  
C. Giacobbe ◽  
I. Calcaterra ◽  
...  
Keyword(s):  
Apob Gene ◽  
Pathogenic Variants ◽  
In Vitro Characterization

Screening of LDLR and APOB gene mutations in Mexican patients with homozygous familial hypercholesterolemia

2018 ◽  
Vol 12 (3) ◽  
pp. 693-701 ◽  
Author(s):  
Teresita De Jesús Hernández Flores ◽  
Juan Ramón González García ◽  
Ana Gabriela Colima Fausto ◽  
Norma Alejandra Vázquez Cárdenas ◽  
Yoaly Sánchez López ◽  
...  
Keyword(s):  
Familial Hypercholesterolemia ◽  
Gene Mutations ◽  
Homozygous Familial Hypercholesterolemia ◽  
Apob Gene ◽  
Mexican Patients

scholarly journals Characterization of the promoter elements required for hepatic and intestinal transcription of the human apoB gene: definition of the DNA-binding site of a tissue-specific transcriptional factor.

1990 ◽  
Vol 10 (6) ◽  
pp. 2653-2659 ◽  
Author(s):  
D Kardassis ◽  
M Hadzopoulou-Cladaras ◽  
D P Ramji ◽  
R Cortese ◽  
V I Zannis ◽  
...  
Keyword(s):  
Binding Site ◽  
Regulatory Elements ◽  
Apob Gene ◽  
Mobility Shift ◽  
Promoter Elements ◽  
Nuclear Extracts ◽  
Dna Binding Site ◽  
Gene Definition ◽  
Definition Of ◽  
Electrophoretic Mobility Shift Assays

The promoter elements important for intestinal and hepatic transcription of the human apoB gene have been localized downstream of nucleotide -150. Footprinting analysis using hepatic nuclear extracts identified four protected regions, -124 to -100, -97 to -93, -86 to -33, and +33 to +52. Gel electrophoretic mobility shift assays showed that multiple factors interact with the apoB sequence -86 to -33, while the region -88 to -61 binds a single nuclear factor. Methylation interference analysis and nucleotide substitution mutagenesis identified the binding site of the factor between residues -78 and -68. Binding competition experiments indicate that this factor recognizes the regulatory elements of other liver-specific genes.

First report of APOB gene variations in Moroccans

2012 ◽  
Vol 4 (4) ◽  
pp. 110
Author(s):  
Fatiha Benyahya ◽  
Amina Barakat ◽  
Naima Ghailani ◽  
HadbaA Echchaoui ◽  
Bouchrail Echchaoui ◽  
...  
Keyword(s):  
Apob Gene ◽  
First Report

Familial hypobetalipoproteinemia: Analysis of three Spanish cases with two new mutations in the APOB gene

Gene ◽  
2013 ◽  
Vol 531 (1) ◽  
pp. 92-96 ◽  
Author(s):  
R. Martín-Morales ◽  
J.D. García-Díaz ◽  
P. Tarugi ◽  
P. González-Santos ◽  
P. Saavedra-Vallejo ◽  
...  
Keyword(s):  
Apob Gene ◽  
Familial Hypobetalipoproteinemia ◽  
New Mutations

Abstract: P841 NON-FUNCTIONALITY OF THREE LDL-R AND APOB GENE MUTATIONS THAT WERE ASSUMED TO CAUSE FAMILIAL HYPERCHOLESTEROLEMIA

2009 ◽  
Vol 10 (2) ◽  
pp. e1231
Author(s):  
R Huijgen ◽  
I Kindt ◽  
S Fouchier ◽  
J Defesche ◽  
B Hutten ◽  
...  
Keyword(s):  
Familial Hypercholesterolemia ◽  
Gene Mutations ◽  
Apob Gene

Apolipoprotein B (APOB) Gene Polymorphism in Patients with Gallbladder Disease

2007 ◽  
Vol 38 (3) ◽  
pp. 360-363 ◽  
Author(s):  
Mateusz Kurzawski ◽  
Zygmunt Juzyszyn ◽  
Andrzej Modrzejewski ◽  
Andrzej Pawlik ◽  
Marek Wiatr ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Apolipoprotein B ◽  
Gallbladder Disease ◽  
Apob Gene
Sign in / Sign up

Export Citation Format

Share Document