scholarly journals Hepatic Granuloma

2020 ◽  
Author(s):  
Keyword(s):  
Hepatic Granuloma

False Positive Ultrasonic Cholecystogram Caused by Hepatic Granuloma

1985 ◽  
Vol 13 (9) ◽  
pp. 659-661
Author(s):  
John E. Williams ◽  
Richard E. Kinard ◽  
Gerhard Moeller ◽  
William W. Orrison
Keyword(s):  
False Positive ◽  
Hepatic Granuloma

scholarly journals Erosive Arthritis and Hepatic Granuloma Formation Induced by Peptidoglycan Polysaccharide in Rats Is Aggravated by Prasugrel Treatment

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69093 ◽  
Author(s):  
Analia E. Garcia ◽  
Mario C. Rico ◽  
Elisabetta Liverani ◽  
Raul A. DeLa Cadena ◽  
Paul F. Bray ◽  
...  
Keyword(s):  
Granuloma Formation ◽  
Hepatic Granuloma ◽  
Erosive Arthritis

scholarly journals FOLFOX and capecitabine-induced hepatic granuloma mimicking metastasis in a rectal cancer patient

2020 ◽  
Vol 13 (3) ◽  
pp. e232628 ◽  
Author(s):  
Vinu Sarathy ◽  
Rajesh Kumar Kothandath Shankar ◽  
Suhail Sayeed Mufti ◽  
Radheshyam Naik
Keyword(s):  
Rectal Cancer Patient ◽  
Liver Lesion ◽  
Chemotherapeutic Agents ◽  
Emission Tomography ◽  
Hepatic Granuloma ◽  
Sinusoidal Dilatation ◽  
Positron Emission ◽  
Medical Oncologists ◽  
Carcinoma Rectum

A 49-year-old male carcinoma rectum patient was treated with neoadjuvant FOLFOX (folinic acid, fluorouracil (5-FU) and oxaliplatin) chemotherapy, chemoradiotherapy with capecitabine, surgery and adjuvant FOLFOX. On follow-up, the patient developed a metabolically active liver lesion mimicking metastasis. Liver biopsy and histopathology showed sinusoidal dilatation with non-caseating granulomas. Follow-up fluorodeoxyglucose positron-emission tomography CT scan demonstrated increase in size of the lesion with metabolic activity suspicious of metastasis. The patient underwent segmental liver resection and histopathology showed non-necrotising granuloma with no evidence of malignancy. It is crucial to consider potential side effects of chemotherapeutic agents and have an unbiased approach when evaluating new liver lesions during post treatment follow-up of colorectal cancer. A multidisciplinary tumour board approach comprising of gastroenterologists, medical oncologists, pathologists, radiologists and surgeons is suggested in the management of such patients. The patient is currently doing well and on regular follow-up.

Protective capacity of cercarial transformation fluid alone or in combination with crude cercarial antigen against challenge infections ofSchistosoma mansoniin mice

2016 ◽  
Vol 91 (1) ◽  
pp. 35-42 ◽  
Author(s):  
M.Z. El Azzouni ◽  
R.F. Mady ◽  
M.R. Gaafar ◽  
F.M. Arafa ◽  
A. Elhadidi
Keyword(s):  
Liver Enzymes ◽  
Immune Status ◽  
Alanine Transaminase ◽  
Parasitic Disease ◽  
Hepatic Granuloma ◽  
Significant Elevation ◽  
Protective Capacity ◽  
Vaccination Strategies ◽  
Schistosomiasis Mansoni ◽  
The World

AbstractSchistosomiasis is the second major parasitic disease in the world after malaria. It affects 201.5 million cases in Africa alone. The aim of this research was to explore alternative vaccination strategies against experimental schistosomiasis mansoni. We assessed the effect of cercarial transformation fluid (CTF) singly and in combination with crude cercarial antigen (CCA) using alum as an adjuvant. The combined antigens gave the best results, as evidenced by a significant reduction in the worm load (62.07%), tissue egg count (78.16%, 86.46%) in liver and intestine respectively, and hepatic granuloma size (29.96%). Scanning electron microscopy revealed changes in the tegument, in the form of roughness and appearance of vesicles and furrows between the tegumental tubercles. Also, resorption of the ventral sucker and dimples replacing its spines were observed. The female tegument was irregular and its posterior end showed loss of spines and sensory bulbs. Moreover, there was a significant decrease in liver enzymes (alanine transaminase (ALT) and aspartate transaminase (AST)) compared to infected control mice. A significant elevation in CD4+T-lymphocytes, denoting amelioration of the immune status, in mice that received combined antigens was also observed. It can be concluded that combined antigens demonstrate potential as a vaccine againstSchistosoma mansoni.

scholarly journals NK Cells and Gamma Interferon Coordinate the Formation and Function of Hepatic Granulomas in Mice Infected with the Francisella tularensis Live Vaccine Strain

2008 ◽  
Vol 76 (4) ◽  
pp. 1379-1389 ◽  
Author(s):  
Sirosh M. Bokhari ◽  
Kee-Jun Kim ◽  
David M. Pinson ◽  
Joyce Slusser ◽  
Hung-Wen Yeh ◽  
...  
Keyword(s):  
Cell Death ◽  
Nk Cells ◽  
Francisella Tularensis ◽  
Vaccine Strain ◽  
Live Vaccine Strain ◽  
Hepatic Granuloma ◽  
Hepatic Granulomas ◽  
Ifn Γ ◽  
And Function ◽  
Deficient Mice

ABSTRACT Host innate immune responses to many intracellular pathogens include the formation of inflammatory granulomas that are thought to provide a physical barrier between the microbe and host. Because two common features of infections with the live vaccine strain (LVS) of Francisella tularensis within the mouse liver are the formation of granulomas and the production of gamma interferon (IFN-γ), we have asked what role IFN-γ plays in hepatic granuloma formation and function. Francisella antigens were predominantly localized within granulomas of the livers of mice infected with F. tularensis LVS 4 days postinfection. Hepatic granulomas also contained large numbers of dying cells, some of which coexpressed the F4/80 macrophage antigen and activated caspase-3. IFN-γ-deficient mice did not form normal numbers of hepatic granulomas and showed widely disseminated Francisella antigens within the liver. The incidence of cell death within hepatic granulomas also decreased significantly in the absence of IFN-γ. Inducible NO synthase (iNOS) expression was restricted to the granulomas of wild-type mice but was not seen for IFN-γ-deficient mice. Cell death within granulomas was also significantly decreased for iNOS-deficient mice. The predominant IFN-γ-expressing cells in the liver were NK cells. Depleting NK cells resulted in the expression of bacterial antigens and iNOS outside the granulomas and the appearance of extensive hepatic focal necrosis. These findings indicate that IFN-γ and hepatic NK cells that are activated during F. tularensis LVS infections regulate hepatic granuloma formation, the spatial containment of infection, the expression of iNOS, and the induction of cell death within the liver.

Hepatic granuloma in Turkish adults: A report of 13 cases

2008 ◽  
Vol 19 (7) ◽  
pp. 527-530 ◽  
Author(s):  
Ibrahim Koral Onal ◽  
Osman Ersoy ◽  
Musa Aydınlı ◽  
Ozlem Yonem ◽  
Ozgur Harmancı ◽  
...  
Keyword(s):  
Hepatic Granuloma

Isolated hepatic granuloma mimicking congenital simple cyst of the liver possibly caused by tuberculosis

1992 ◽  
Vol 27 (12) ◽  
pp. 1553-1556 ◽  
Author(s):  
Z.Hülya Gündoǧdu ◽  
M.Emin Şenocak ◽  
Melda Çaǧlar ◽  
Nebil Büyükpamukçu
Keyword(s):  
Hepatic Granuloma ◽  
Simple Cyst
Sign in / Sign up

Export Citation Format

Share Document