Chlormadinone Acetate

2020 ◽  
Author(s):  
GYNECOLOGY ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 17-21
Author(s):  
Tatyana Yu Pestrikova ◽  
Elena A Yurasova ◽  
Igor V Yurasov ◽  
Tamara D Kovaleva

Relevance. Currently, women make up more than 40% of the global workforce and more than half of students studying at universities around the world. Women's education, especially at a high level, tends to increase female employment. The mismatch of the style and rhythm of modern life with a genetically determined and working millennium reproductive program requires the choice of a specific approach to social adaptation. Aim. Analysis of literary sources on the use of hormonal contraception as a method of social adaptation. Materials and methods. To write this review, domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 2-10 years. The review included articles from peer-reviewed literature. Results. The review describes the features of modern hormonal contraceptives. Their non-contraceptive effects are presented. The individual non-contraceptive effects of a combined oral contraceptive containing 30 mg of ethinyl estradiol and 2 mg of chlormadinone acetate were determined. It has been established that the use of this contraceptive helps to improve the well-being and mood of patients, which allows you to actively use this contraceptive in routine clinical practice with premenstrual syndrome, dysmenorrhea, without the use of analgesics. Conclusions. The numerous positive effects of ethinyl estradiol and chlormadinone acetate allow the use of the drug as a means to increase social adaptation, and, consequently, improve the quality of life.


2017 ◽  
Vol 223 ◽  
pp. 346-356 ◽  
Author(s):  
Patricia Franziska Siegenthaler ◽  
Yanbin Zhao ◽  
Kun Zhang ◽  
Karl Fent

1971 ◽  
Vol 66 (2) ◽  
pp. 221-228 ◽  
Author(s):  
Dona A. Frith ◽  
K. C. Hooper

ABSTRACT The previous paper (Frith & Hooper 1971) described the activities of certain hypothalamic enzymes at various times after mating and it was suggested that changes in enzymes levels may be used as an index of the release of gonadotrophic hormones. Using this approach, a study has been made of the action of the ovulation inhibitors chlormadinone acetate, norethindrone, ethinyl oestradiol and oestrone on the rabbit hypothalamus. The four inhibitors increased enzyme activity in the hypothalamus. Previous work has shown that raised levels of enzyme activity are associated with a lowered level of gonadotrophic hormone secretion. It is suggested, therefore, that one of the sites of action of the inhibitors is on polypeptide turnover in the hypothalamus, and it seems possible that this is one of the factors controlling the availability of gonadotrophin releasing factors.


2004 ◽  
Vol 153 (2) ◽  
pp. 221-225 ◽  
Author(s):  
Yasir Hasan Siddique ◽  
Mohammad Afzal

1997 ◽  
Vol 50 (12) ◽  
pp. 725-728
Author(s):  
Yoshihiko KOJIMA ◽  
Shizuo KAWAKAMI ◽  
Masao SHINO

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