scholarly journals Brain Nucleus

2020 ◽  
Author(s):  
Keyword(s):  
Brain Nucleus

scholarly journals An inexpensive drivable cannulated microelectrode array for simultaneous unit recording and drug infusion in the same brain nucleus of behaving rats

2011 ◽  
Vol 106 (2) ◽  
pp. 1054-1064 ◽  
Author(s):  
Johann du Hoffmann ◽  
James J. Kim ◽  
Saleem M. Nicola
Keyword(s):  
Microelectrode Array ◽  
Drug Effects ◽  
Precise Determination ◽  
Drug Infusion ◽  
Neural Basis ◽  
Unit Recording ◽  
Brain Nucleus ◽  
Neural Ensemble ◽  
Discrete Populations

Neurons are functionally segregated into discrete populations that perform specific computations. These computations, mediated by neuron-neuron electrochemical signaling, form the neural basis of behavior. Thus fundamental to a brain-based understanding of behavior is the precise determination of the contribution made by specific neurotransmitters to behaviorally relevant neural activity. To facilitate this understanding, we have developed a cannulated microelectrode array for use in behaving rats that enables simultaneous neural ensemble recordings and local infusion of drugs in the same brain nucleus. The system is inexpensive, easy to use, and produces robust and quantitatively reproducible drug effects on recorded neurons.

The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network

Science ◽  
1986 ◽  
Vol 234 (4777) ◽  
pp. 734-737 ◽  
Author(s):  
G Aston-Jones ◽  
M Ennis ◽  
V. Pieribone ◽  
W. Nickell ◽  
M. Shipley
Keyword(s):  
Locus Coeruleus ◽  
Brain Nucleus ◽  
The Brain ◽  
Afferent Control

1H NMR-based metabonomics in brain nucleus accumbens and striatum following repeated cocaine treatment in rats

Neuroscience ◽  
2012 ◽  
Vol 218 ◽  
pp. 196-205 ◽  
Author(s):  
Y. Li ◽  
G.-Y. Yan ◽  
J.-Q. Zhou ◽  
Q. Bu ◽  
P.-C. Deng ◽  
...  
Keyword(s):  
Nucleus Accumbens ◽  
1H Nmr ◽  
Brain Nucleus

Population coding of song element sequence in the songbird brain nucleus HVC

2007 ◽  
Vol 58 ◽  
pp. S44 ◽  
Author(s):  
Jun Nishikawa ◽  
Masato Okada ◽  
Kazuo Okanoya
Keyword(s):  
Population Coding ◽  
Brain Nucleus ◽  
Element Sequence

Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius

2006 ◽  
Vol 24 (1) ◽  
pp. 45-58 ◽  
Author(s):  
Maria Yolanda Covarrubias ◽  
Rishi L. Khan ◽  
Rajanikanth Vadigepalli ◽  
Jan B. Hoek ◽  
James S. Schwaber
Keyword(s):  
Gene Expression ◽  
Signaling Pathways ◽  
Differentially Expressed Genes ◽  
Nucleus Tractus Solitarius ◽  
Expression Patterns ◽  
Alcohol Exposure ◽  
Differentially Expressed ◽  
Chronic Alcohol ◽  
Brain Nucleus ◽  
Chronic Alcohol Exposure

Chronic exposure to alcohol modifies physiological processes in the brain, and the severe symptoms resulting from sudden removal of alcohol from the diet indicate that these modifications are functionally important. We investigated the gene expression patterns in response to chronic alcohol exposure (21–28 wk) in the rat nucleus tractus solitarius (NTS), a brain nucleus with a key integrative role in homeostasis and cardiorespiratory function. Using methods and an experimental design optimized for detecting transcriptional changes less than twofold, we found 575 differentially expressed genes. We tested these genes for significant associations with physiological functions and signaling pathways using Gene Ontology terms and the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, respectively. Chronic alcohol exposure resulted in significant NTS gene regulation related to the general processes of synaptic transmission, intracellular signaling, and cation transport as well as specific neuronal functions including plasticity and seizure behavior that could be related to alcohol withdrawal symptoms. The differentially expressed genes were also significantly enriched for enzymes of lipid metabolism, glucose metabolism, oxidative phosphorylation, MAP kinase signaling, and calcium signaling pathways from KEGG. Intriguingly, many of the genes we found to be differentially expressed in the NTS are known to be involved in alcohol-induced oxidative stress and/or cell death. The study provides evidence of very extensive alterations of physiological gene expression in the NTS in the adapted state to chronic alcohol exposure.

Early-life stress affects song complexity, song learning and volume of the brain nucleus RA in adult male song sparrows

2013 ◽  
Vol 86 (1) ◽  
pp. 25-35 ◽  
Author(s):  
Kim L. Schmidt ◽  
S. Drew Moore ◽  
Elizabeth A. MacDougall-Shackleton ◽  
Scott A. MacDougall-Shackleton
Keyword(s):  
Adult Male ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Song Learning ◽  
Male Song ◽  
Song Complexity ◽  
Song Sparrows ◽  
Brain Nucleus ◽  
The Brain

DEVELOPMENT OF A BRAIN NUCLEUS INVOLVED IN SONG PRODUCTION IN ZEBRA FINCHES (TAENIOPYGIA GUTTATA) IS DISRUPTED BY AROCLOR 1248

2008 ◽  
Vol 27 (10) ◽  
pp. 2071 ◽  
Author(s):  
Almira L. Hoogesteijn ◽  
George V. Kollias ◽  
Fred W. Quimby ◽  
Anthony P. De Caprio ◽  
David W. Winkler ◽  
...  
Keyword(s):  
Taeniopygia Guttata ◽  
Zebra Finches ◽  
Aroclor 1248 ◽  
Brain Nucleus ◽  
Song Production
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