scholarly journals Chamomile Flower Oil

2020 ◽  
Author(s):  
Keyword(s):  
Chamomile Flower

scholarly journals Clinical-pharmacological aspects of the choice of phytocomponents for the regulation of the gastrointestinal function

2021 ◽  
pp. 158-163
Author(s):  
E. V. Shikh ◽  
S. M. Rykova ◽  
N. V. Shikh
Keyword(s):  
Water Solubility ◽  
Clinical Symptoms ◽  
Primary Tumour ◽  
Gastrointestinal Diseases ◽  
Gastric Glands ◽  
Flower Extract ◽  
Anti Inflammatory ◽  
Mechanisms Of Development ◽  
Chamomile Flower ◽  
Inflammatory Effect

The presentations of dyspepsia include a range of clinical symptoms, each of which has different mechanisms of development, and, therefore, requires different approaches to the correction. In this context, the combination preparations containing components of natural origin with polymodal action on the gastrointestinal tract deserve special attention. Combination of synergistic components: highly bioavailable curcumin and prebiotic fibers; artichoke leaf extract and chamomile flower extract provide simultaneous effects on three key digestive organs: stomach, pancreas and liver. Curcumin has an anti-inflammatory effect, helps to normalize acidity and restore microflora; epithelialization of ulcers; normalization of the gallbladder function; elimination of toxins. It inhibits the processes of primary tumour formation and prevents the development of metastatic processes in gastrointestinal cancer. Pharmaceutical technologies using cyclodextrin as an excipient increase curcumin’s water solubility, dispersibility and absorption, which has been confirmed in several comparative bioavailability studies in healthy volunteers. Chamomile flower extract has anti-inflammatory, antimicrobial, antispasmodic, antiulcer, wound healing and astringent effects. Chamomile is rich in slimy substances that envelop and protect the inflamed mucous membrane, including the stomach, from irritation with hydrochloric acid, bile components, food, and drugs. Mucous substances also have an anti-inflammatory effect and improve digestion. The artichoke facilitates the outflow of bile, affects the secretion of gastric glands, pancreas, increases the enzymatic activity of gastric juice, enhances intestinal motility during its atony, and has a hepatoprotective effect. As can be seen from the above, a combination of these synergistic components can be used in patients with chronic diseases, functional disorders as part of combination therapy, as well as for the prevention of gastrointestinal diseases in healthy people.

scholarly journals Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa

Biomolecules ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1033 ◽  
Author(s):  
Laura Weber ◽  
Katrin Kuck ◽  
Guido Jürgenliemk ◽  
Jörg Heilmann ◽  
Bartosz Lipowicz ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Barrier Function ◽  
Inflammatory Mediator ◽  
Cell Model ◽  
Intestinal Barrier ◽  
Culture Cell ◽  
Mediator Release ◽  
Intestinal Epithelial ◽  
Flower Extract ◽  
Chamomile Flower

Recent clinical evidence suggests the efficacy of a traditional herbal medicinal product containing myrrh (Commiphora molmol Engl.), coffee charcoal (Coffea arabica L.) and chamomile flower dry extract (Matricaria chamomilla L.) in the therapy of inflammatory bowel diseases (IBD). However, the mechanisms of action in this context have not been entirely elucidated. The present study aimed to evaluate the effects of myrrh, coffee charcoal and chamomile flower extract on the inflammatory cross talk between immune and intestinal epithelial cells together with the resulting intestinal barrier disorders. A complex co-culture cell model consisting of intestinal epithelial cell (IEC) monolayers (Caco-2, HT29-MTX-E12) and macrophages (THP-1) was established for the simultaneous investigation of these two IBD characteristics. The lipopolysaccharide (LPS) activation of the macrophages led to a pro-inflammatory mediator release and thereby an inflammatory stimulation of IECs with chemokine release and reduced barrier function. The effects of the individual plant extracts and a ternary combination on inflammatory mediator release (IL-6, TNF, IL-8, MCP-1, PGE2) was quantified by ELISA. The transepithelial electrical resistance (TEER) of IEC monolayers was measured to evaluate the effects on the barrier function. Budesonide served as a positive control. All three plant extracts exhibited anti-inflammatory properties via the inhibition of the inflammatory mediator release to a varying extent. An intestinal barrier stabilising effect was observed for myrrh and coffee charcoal. Myrrh exerted the most distinct pharmacological activity. Dose reducing and synergistic interactions emerged within the threefold combination. Thus, our results provide a mechanistic basis for the use of the herbal combination of myrrh, coffee charcoal and chamomile flower extract in IBD treatment and underline the potential benefits of the phytotherapeutic multi-component/multi-target approach in this complex pathogenesis.

Synergistic Interaction between Chamomile Flower (Matricaria chamomilla L.) Extracts and Tetracycline Against Wound Infection Bacteria

2013 ◽  
Vol 16 (3) ◽  
pp. 191-195 ◽  
Author(s):  
Munira CH. Ismail ◽  
◽  
Sinai Waleed ◽  
Khawla Ibrahim ◽  
Noor Ulhuda Fakhri ◽  
...  
Keyword(s):  
Wound Infection ◽  
Synergistic Interaction ◽  
Matricaria Chamomilla ◽  
Chamomile Flower
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