scholarly journals Cefotetan Disodium

2020 ◽  
Author(s):  
Keyword(s):  
Cefotetan Disodium

scholarly journals Pharmacokinetics and Tolerability of Single and Multiple Intravenous Doses of Cefotetan Disodium in Healthy Chinese Volunteers

2020 ◽  
Vol Volume 14 ◽  
pp. 613-620
Author(s):  
Jian Liu ◽  
You Zhai ◽  
Lihua Wu ◽  
Guolan Wu ◽  
Yunliang Zheng ◽  
...  
Keyword(s):  
Healthy Chinese ◽  
Cefotetan Disodium

An embryotoxicity study in Macaca fascicularis with cefotetan disodium (a cephamycin antibiotic)

1982 ◽  
Vol 11 (1-2) ◽  
pp. 43-47 ◽  
Author(s):  
D.G. Allen ◽  
R. Clark ◽  
A.K. Palmer ◽  
R. Heywood
Keyword(s):  
Macaca Fascicularis ◽  
Cefotetan Disodium

The effects of cefotetan disodium on haemostatis

1987 ◽  
Vol 10 (1) ◽  
pp. 51-57 ◽  
Author(s):  
H. Cohen ◽  
I.J. Mackie ◽  
K. Walshe ◽  
M. Shearer ◽  
R. Bax ◽  
...  
Keyword(s):  
Cefotetan Disodium

Cefotetan-Induced Hemolytic Anemia

2000 ◽  
Vol 124 (9) ◽  
pp. 1344-1346 ◽  
Author(s):  
Gregory Scott Moes ◽  
Bruce R. MacPherson
Keyword(s):  
Flow Cytometry ◽  
Respiratory Failure ◽  
Small Bowel ◽  
Hemolytic Anemia ◽  
Blood Transfusions ◽  
Objective Method ◽  
Drug Induced ◽  
Serum Dilution ◽  
Specific Antibodies ◽  
Cefotetan Disodium

Abstract Cefotetan disodium–induced hemolytic anemia has been reported previously, and some of these cases have been severe or fatal. We describe a case of severe hemolytic anemia that occurred in an 80-year-old woman who received cefotetan prophylactically after surgery for a small bowel obstruction. Eight days after the first dose of cefotetan, the patient developed a severe Coomb test–positive hemolytic anemia. Using flow cytometry, we demonstrated cefotetan-specific antibodies in her posttreatment serum, which were detectable at a serum dilution up to 1:10 000. The patient received corticosteroid therapy and blood transfusions, with improvement of her hematologic parameters, but died 54 days after admission for respiratory failure. To our knowledge, this is the first use of flow cytometry for the detection of cefotetan-induced red blood cell antibodies. This technique offers a sensitive, rapid, objective method for detecting drug-induced antibodies.

Pharmacokinetics and tolerance of single intravenous doses of cefotetan disodium in male Caucasian volunteers

1983 ◽  
Vol 11 (suppl A) ◽  
pp. 185-191 ◽  
Author(s):  
R. A. Yates ◽  
H. K. Adam ◽  
R. J. Donnelly ◽  
H. L. Houghton ◽  
E. A. Charlesworth ◽  
...  
Keyword(s):  
Cefotetan Disodium
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