scholarly journals Mouse Kidney Carcinoma

2020 ◽  
Author(s):  
Keyword(s):  
Mouse Kidney ◽  
Kidney Carcinoma

Video rate optoacoustic tomography of mouse kidney perfusion

2010 ◽  
Vol 35 (14) ◽  
pp. 2475 ◽  
Author(s):  
Andreas Buehler ◽  
Eva Herzog ◽  
Daniel Razansky ◽  
Vasilis Ntziachristos
Keyword(s):  
Mouse Kidney ◽  
Optoacoustic Tomography ◽  
Kidney Perfusion

scholarly journals Mouse Kidney Cytidine Deaminase

1968 ◽  
Vol 243 (10) ◽  
pp. 2534-2537
Author(s):  
R Tomchick ◽  
L D Saslaw ◽  
V S Waravdekar
Keyword(s):  
Cytidine Deaminase ◽  
Mouse Kidney

YAP1 Overexpression Is Associated with Kidney Dysfunction in Lupus Nephritis

Pathobiology ◽  
2021 ◽  
pp. 1-12
Author(s):  
Ying Xie ◽  
Yuanyuan Ruan ◽  
Huimei Zou ◽  
Yixin Wang ◽  
Xin Wu ◽  
...  
Keyword(s):  
Lupus Nephritis ◽  
Epithelial Mesenchymal Transition ◽  
Kidney Tissue ◽  
Mouse Kidney ◽  
Experimental Comparison ◽  
Control Group ◽  
Mrna Levels ◽  
Mesenchymal Transition ◽  
Protein Levels

<b><i>Objective:</i></b> The goal of the present study was to determine the expression of yes-associated protein 1 (YAP1) in renal tissues of mice with lupus nephritis (LN) and elucidate its role in the progression of renal fibrosis. <b><i>Methods:</i></b> C57BL/6 mice and MRL/lpr mice were selected for experimental comparison. Mouse kidney tissues were removed and sectioned for hematoxylin and eosin staining, Masson’s trichome staining, Sirius staining, and immunohistochemistry. The mRNA and protein levels of YAP1 in mouse kidney tissues were detected, and the correlation between YAP1 and fibronectin (FN) mRNA levels was analyzed. Mouse renal epithelial cells were used for in vitro experiments. After transfection and stimulation, the cells were divided into 4 groups, namely the C57BL/6 serum group (group 1), the MRL/lpr serum group (group 2), the MRL/lpr serum + siRNA-negative control group (group 3), and the MRL/lpr serum + siRNA-YAP1 group (group 4). Epithelial-mesenchymal transition (EMT) markers in each group were detected by Western blotting and immunofluorescence staining. Serum creatinine, blood urea nitrogen, and urinary protein levels were detected and assessed for their correlation with YAP1 mRNA levels by Spearman’s analysis. <b><i>Results:</i></b> Compared to C57BL/6 mice, MRL/lpr mice exhibited obvious changes in fibrosis in renal tissues. In addition, YAP1 expression was significantly higher in the renal tissues of MRL/lpr mice than in those of C57BL/6 mice, and YAP1 mRNA levels were positively correlated with those of FN. YAP1 silencing in lupus serum-stimulated cells could effectively relieve serum-induced EMT. Finally, we observed that YAP1 mRNA levels in mouse kidney tissue were significantly and positively correlated with the degree of renal function injury. <b><i>Conclusion:</i></b> YAP1 expression in the kidney tissues of LN mice was higher than that observed in normal mice, indicating that YAP1 may play an important role in the occurrence and development of LN.

A combined morphometric approach to feature mouse kidney vasculature

2021 ◽  
pp. 151727
Author(s):  
A. Palladino ◽  
C. Pizzoleo ◽  
I. Mavaro ◽  
Carla Lucini ◽  
Livia D’Angelo ◽  
...  
Keyword(s):  
Mouse Kidney

scholarly journals Gene expression in normal and regenerating mouse kidney.

1979 ◽  
Vol 254 (3) ◽  
pp. 742-748 ◽  
Author(s):  
W.L. Miller ◽  
B.J. McCarthy
Keyword(s):  
Gene Expression ◽  
Mouse Kidney

scholarly journals Synthesis of Galactosylceramide and Glucosylceramide by Mouse Kidney Preparations

1973 ◽  
Vol 248 (23) ◽  
pp. 8240-8246 ◽  
Author(s):  
Elvira Costantino-Ceccarini ◽  
Pierre Morell
Keyword(s):  
Mouse Kidney
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