scholarly journals Maternal riboflavin deficiency

2020 ◽  
Author(s):  
Keyword(s):  
Riboflavin Deficiency

Drug Induced Changes in Cell Organelles

1968 ◽  
Vol 26 ◽  
pp. 110-111
Author(s):  
Sarah A. Luse
Keyword(s):  
Clinical Medicine ◽  
Cell Organelles ◽  
Riboflavin Deficiency ◽  
Drug Induced ◽  
New Era ◽  
Health And Disease ◽  
In The Beginning ◽  
Cellular Pathology ◽  
Induced Changes ◽  
The Impact

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.

scholarly journals EFFECTS OF RIBOFLAVIN DEFICIENCY AND REALIMENTATION ON FLAVIN ENZYMES OF TISSUES

1956 ◽  
Vol 223 (1) ◽  
pp. 29-45 ◽  
Author(s):  
Helen B. Burch ◽  
Oliver H. Lowry ◽  
Ana M. Padilla ◽  
Anne M. Combs
Keyword(s):  
Riboflavin Deficiency

scholarly journals STUDIES ON THE SUCCINOXIDASE SYSTEM OF RAT LIVER IN RIBOFLAVIN DEFICIENCY

1942 ◽  
Vol 145 (1) ◽  
pp. 297-307 ◽  
Author(s):  
A.E. Axelrod ◽  
Karl F. Swingle ◽  
C.A. Elvehjem
Keyword(s):  
Rat Liver ◽  
Riboflavin Deficiency

Early paranodal myelin swellings (tomacula) in an avian riboflavin deficiency model of demyelinating neuropathy

2006 ◽  
Vol 198 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Z. Cai ◽  
J.W. Finnie ◽  
P.C. Blumbergs ◽  
J. Manavis ◽  
M.N. Ghabriel ◽  
...  
Keyword(s):  
Demyelinating Neuropathy ◽  
Riboflavin Deficiency

Chronic Riboflavin Deficiency in the Rat. I. Ossification in the Proximal Tibial Epiphysis.

1947 ◽  
Vol 66 (3) ◽  
pp. 631-635 ◽  
Author(s):  
M. M. Nelson ◽  
E. Sulon ◽  
H. Becks ◽  
H. M. Evans
Keyword(s):  
Riboflavin Deficiency ◽  
Tibial Epiphysis

scholarly journals Probiotic Potential of a Novel Vitamin B2-Overproducing Lactobacillus plantarum Strain, HY7715, Isolated from Kimchi

2021 ◽  
Vol 11 (13) ◽  
pp. 5765
Author(s):  
Joo-Yun Kim ◽  
Eun-Jung Choi ◽  
Jae-Ho Lee ◽  
Myeong-Seok Yoo ◽  
Keon Heo ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Lactobacillus Plantarum ◽  
Probiotic Strain ◽  
Optimal Growth ◽  
Control Group ◽  
High Survival ◽  
Vitamin B2 ◽  
Riboflavin Deficiency

Vitamin B2, also known as riboflavin, is essential for maintaining human health. The purpose of this study was to isolate novel lactic acid bacteria that overproduce vitamin B2 and to validate their potential as probiotics. In this study, Lactobacillus plantarum HY7715 (HY7715) was selected among lactic acid bacteria isolated from Kimchi. HY7715 showed a very high riboflavin-producing ability compared to the control strain due to the high expression of ribA, ribB, ribC, ribH, and ribG genes. HY7715 produced 34.5 ± 2.41 mg/L of riboflavin for 24 h without consuming riboflavin in the medium under optimal growth conditions. It was able to produce riboflavin in an in vitro model of the intestinal environment. In addition, when riboflavin deficiency was induced in mice through nutritional restriction, higher levels of riboflavin were detected in plasma and urine in the HY7715 administration group than in the control group. HY7715 showed high survival rate in simulated gastrointestinal conditions and had antibiotic resistance below the cutoff MIC value suggested by the European Food Safety Authority; moreover, it did not cause hemolysis. In conclusion, HY7715 could be considered a beneficial probiotic strain for human and animal applications, suggesting that it could be a new alternative to address riboflavin deficiency.

Effect of Riboflavin Deficiency on the Metabolism of Oxypurines in Chicks

1971 ◽  
Vol 49 (12) ◽  
pp. 1059-1062 ◽  
Author(s):  
S. T. Chou
Keyword(s):  
Uric Acid ◽  
Acid Synthesis ◽  
Xanthine Dehydrogenase ◽  
Broiler Chicks ◽  
Uric Acid Concentration ◽  
Riboflavin Deficiency ◽  
Deficient Diet ◽  
High Incidence ◽  
Liver And Kidney ◽  
Riboflavin Deficient

Day-old broiler chicks of both sexes were used in three experiments to determine the effect of riboflavin deficiency on oxypurine metabolism catalyzed by xanthine dehydrogenase, a riboflavin-containing enzyme. Chicks fed a riboflavin-deficient diet (1.38 mg/kg) for 3 weeks exhibited depressed growth and a high incidence of curled-toe paralysis (higher than 80%) as compared to control chicks (15.1 mg riboflavin per kilogram diet; no incidence of curled-toe paralysis). In addition, the precursors of uric acid, hypoxanthine and/or xanthine, accumulated in the liver and kidney of deficient chicks showing curled-toe paralysis. These observations show that dietary riboflavin being incorporated into xanthine dehydrogenase is essential for oxypurine metabolism. Moreover in the chick, the liver and the kidney may be important sites of uric acid synthesis. The low uric acid concentration in the plasma of the deficient chicks appeared to be indicative of a disturbance in uric acid synthesis in the liver and kidney.

scholarly journals Nutritional status of children, inmates of a small institution for homeless children in the capital of the State of S. Paulo, Brazil

1980 ◽  
Vol 14 (3) ◽  
pp. 300-309 ◽  
Author(s):  
Donald Wilson ◽  
Maria José Roncada ◽  
Rosa Nilda Mazzilli ◽  
Maria Lucia F. Cavalcanti ◽  
Dino B. G. Pattoli
Keyword(s):  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Clinical Signs ◽  
Skin Lesions ◽  
High Rate ◽  
Calorie Intake ◽  
Homeless Children ◽  
Riboflavin Deficiency ◽  
Skinfold Measurement ◽  
Nutritional Status Of Children

Nutritional surveys (food consumption, clinical and biochemichal) were conducted in a small institution for homeless children. Results showed that only 30% of the children presented adequate calorie intake. Most of the children presented adequate protein intake, but almost half consumed less than 2/3 of the calcium RDA considered necessary. Food handling, processing, and distribution also proved inadequate and wastage, high. Skinfold measurement showed up one case of obesity. Furthermore, most of the children presented clinical signs of vitamin A deficiency, mostly skin lesions; while about half presented clinical signs of riboflavin deficiency. Biochemical data showed that 63.6% had deficient plasma levels of vitamin A, none showed abnormal results for riboflavin excretion, four showed packed blood cell volume below normal, and all had normal hemoglobin levels. Stool examinations revealed a high rate of pathogenic protozoa (Hymenolepis nana), in fact, one of the highest in Brazilian literature.

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