Malignant Teratoma

2020 ◽  
Author(s):  
Keyword(s):  
2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Ikuma Nozaki ◽  
Yumi Tone ◽  
Junko Yamanaka ◽  
Hideko Uryu ◽  
Yuko Shimizu-Motohashi ◽  
...  

We report about a 14-year-old boy who presented with an anterior mediastinal mass that was diagnosed as malignant teratoma. Surgical resection was performed along with pre- and postoperative chemotherapy. Although elevated alpha-fetoprotein became negative, he experienced pain in his right hip joint 3 months after resection. Systematic evaluation revealed multiple locations of metastasis, and the pathological diagnosis based on bone biopsy was malignant melanoma originating from malignant teratoma, which rapidly progressed. He died 15 months after diagnosis of the original malignant teratoma. Diagnosing and treating malignant transformation of teratoma, including malignant melanoma, is difficult because it is very rare. To our knowledge, this is the second reported case of malignant melanoma arising from a mediastinum malignant teratoma, with both cases having a poor prognosis. In addition to the follow-up of tumor markers, systematic evaluation, including imaging, should be considered even after remission to monitor malignant transformation of teratoma. We expect to establish a successful therapy and improve mortality rate after more such cases are accumulated.


1978 ◽  
Vol 62 (2) ◽  
pp. 310
Author(s):  
Khoo Boo-Chai ◽  
Z. Petrovich

1977 ◽  
Vol 32 (1) ◽  
pp. 50-52 ◽  
Author(s):  
HENRY J. NORRIS ◽  
HOWARD J. ZIRKIN ◽  
WILLIAM L. BENSON

2021 ◽  
Vol 14 (7) ◽  
pp. e242534
Author(s):  
Rohan Bidaye ◽  
Ashraf Mahmood ◽  
Zainab Abdawn ◽  
Ijaz Ahmad

Malignant thyroid teratoma in adults is a rare tumour with less than 40 cases reported worldwide. Our case is of a 29-year-old man who presented with a thyroid lump and compressive symptoms. He underwent multiple investigations before being diagnosed with a malignant thyroid teratoma. There are no established guidelines in the management of this tumour yet. In this case report, we discuss the diagnosis, treatment and follow-up of the patient and reflect on the published literature on this tumour.


1989 ◽  
Vol 82 (1) ◽  
pp. 54-55
Author(s):  
C K Bushby ◽  
S J Snooks ◽  
W S Shand
Keyword(s):  

1973 ◽  
Vol 38 (3) ◽  
pp. 355-357 ◽  
Author(s):  
Robert J. Morelli

✓ The author reports a rare case in which a primary malignant teratoma presented as an obstructing mass in the fourth ventricle. The tumor was not cystic but well encapsulated, and a gross total surgical removal was accomplished. A fatal recurrence occurred within 3 months.


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