scholarly journals Engineered Nanoparticle

2020 ◽  
Author(s):  
Keyword(s):  
Engineered Nanoparticle

Engineered Nanoparticle Adhesion and Removal from Tomato Surfaces

2013 ◽  
Vol 61 (42) ◽  
pp. 10183-10190 ◽  
Author(s):  
Mahmoudreza Ovissipour ◽  
Shyam S. Sablani ◽  
Barbara Rasco
Keyword(s):  
Engineered Nanoparticle

Airborne engineered nanoparticle mass sensor based on a silicon resonant cantilever

2013 ◽  
Vol 180 ◽  
pp. 77-89 ◽  
Author(s):  
Hutomo Suryo Wasisto ◽  
Stephan Merzsch ◽  
Andreas Waag ◽  
Erik Uhde ◽  
Tunga Salthammer ◽  
...  
Keyword(s):  
Mass Sensor ◽  
Engineered Nanoparticle ◽  
Resonant Cantilever

SERS and plasmon resonance of engineered nanoparticle arrays

2005 ◽  
Author(s):  
D. R. Chamberlin ◽  
Z. Wang ◽  
K. A. Sultana ◽  
E. K. Chow ◽  
M. M. Sigalas ◽  
...  
Keyword(s):  
Plasmon Resonance ◽  
Nanoparticle Arrays ◽  
Engineered Nanoparticle

Transitioning DNA-Engineered Nanoparticle Superlattices from Solution to the Solid State

2012 ◽  
Vol 24 (38) ◽  
pp. 5181-5186 ◽  
Author(s):  
Evelyn Auyeung ◽  
Robert J. Macfarlane ◽  
Chung Hang J. Choi ◽  
Joshua I. Cutler ◽  
Chad A. Mirkin
Keyword(s):  
Solid State ◽  
Engineered Nanoparticle ◽  
Nanoparticle Superlattices

Silicon resonant nanopillar sensors for airborne titanium dioxide engineered nanoparticle mass detection

2013 ◽  
Vol 189 ◽  
pp. 146-156 ◽  
Author(s):  
Hutomo Suryo Wasisto ◽  
Stephan Merzsch ◽  
Andrej Stranz ◽  
Andreas Waag ◽  
Erik Uhde ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Mass Detection ◽  
Engineered Nanoparticle

scholarly journals SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

2021 ◽  
Author(s):  
M. Gordon Joyce ◽  
Kayvon Modjarrad
Keyword(s):  
Neutralizing Antibodies ◽  
Vaccine Development ◽  
Design Strategies ◽  
Virus Challenge ◽  
High Magnitude ◽  
Antigenic Properties ◽  
Blocking Activity ◽  
Antibody Titers ◽  
Engineered Nanoparticle

The need for SARS-CoV-2 next-generation vaccines has been highlighted by the rise of variants of concern (VoC) and the long-term threat of other coronaviruses. Here, we designed and characterized four categories of engineered nanoparticle immunogens that recapitulate the structural and antigenic properties of prefusion Spike (S), S1 and RBD. These immunogens induced robust S-binding, ACE2-inhibition, and authentic and pseudovirus neutralizing antibodies against SARS-CoV-2 in mice. A Spike-ferritin nanoparticle (SpFN) vaccine elicited neutralizing titers more than 20-fold higher than convalescent donor serum, following a single immunization, while RBD-Ferritin nanoparticle (RFN) immunogens elicited similar responses after two immunizations. Passive transfer of IgG purified from SpFN- or RFN-immunized mice protected K18-hACE2 transgenic mice from a lethal SARS-CoV-2 virus challenge. Furthermore, SpFN- and RFN-immunization elicited ACE2 blocking activity and neutralizing ID50 antibody titers >2,000 against SARS-CoV-1, along with high magnitude neutralizing titers against major VoC. These results provide design strategies for pan-coronavirus vaccine development.

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