scholarly journals Tumor Flare Reaction

2020 ◽  
Author(s):  
Keyword(s):  
1991 ◽  
Vol 632 (1 Substance P a) ◽  
pp. 460-463 ◽  
Author(s):  
FR-K. PIERAU ◽  
R. ERNST ◽  
H. SANN ◽  
L. BARTHÓ

2007 ◽  
Vol 25 (31) ◽  
pp. 5047-5047 ◽  
Author(s):  
Laure A. Moutouh-de Parseval ◽  
Lilia Weiss ◽  
Robert J. DeLap ◽  
Robert D. Knight ◽  
Jerome B. Zeldis

Author(s):  
Gerald W. Volcheck

Standard allergy testing relies on identifying the immunoglobulin (Ig) E antibody specific for the allergen in question. Two classic methods of doing this are the immediate wheal-and-flare skin prick tests (in which a small amount of antigen is introduced into the skin and the site is evaluated after 15 minutes for the presence of an immediate wheal-and-flare reaction) and in vitro (blood) testing. Methods of allergy testing that do not have a clear scientific basis include cytotoxic testing, provocation-neutralization testing or treatment, and “yeast allergy” testing.


1999 ◽  
Vol 89 (6) ◽  
pp. 1521
Author(s):  
Wolfgang Koppert ◽  
Susanne Zeck ◽  
James A. Blunk ◽  
Martin Schmelz ◽  
Rudolf Likar ◽  
...  

Author(s):  
Māris Bukovskis ◽  
Madara Tirzīte ◽  
Gunta Strazda ◽  
Normunds Jurka ◽  
Renāte Ligere ◽  
...  

H1-antihistamines suppress wheal-and-flare reaction and skin blood perfusion measured by Laser Dopppler flowmetry: randomized, double-blind, placebo-controlled, crossover design study The aim of our study was to compare the influence of pre-treatment with H1-antihistamines (levocetirizine, desloratadine, clemastine, quifenadine, and sequifenadine) and a placebo on the histamine-induced weal and flare reaction, increase of skin blood perfusion and sedation. Thirty healthy volunteers were enrolled in the study. The study design was a prospective, randomised, double-blind, placebo-controlled, crossover, balanced clinical trial. Volunteers in randomised and double-blind order were treated with oral levocetirizine 5 mg, desloratadine 5 mg, clemastine 1 mg, quifenadine 50 mg, sequifenadine 50 mg or a placebo. Two hours after intake of medication, the histamine skin prick test was performed and skin blood perfusion was registered with further evaluation of sedative effect. We conclude that levocetirizine induced a significant and pronounced decrease of weal and flare reaction and skin blood perfusion compared to the placebo and the other H1-antihistamines. The effect of quifenadine and sequifenadine on weal reaction area was similar to desloratadine and clemastine. Regarding the sedative effect, we can conclude that second generation antihistamines appear to be not non-sedative but the least impairing, and the first generation antihistamines appear to be the most impairing on central nervous system function. There is a necessity to consider the sedating potential of antihistamines, along with other factors such as efficacy, when prescribing antihistamines to patients.


Blood ◽  
2014 ◽  
Vol 123 (8) ◽  
pp. 1159-1166 ◽  
Author(s):  
Christiane Querfeld ◽  
Steven T. Rosen ◽  
Joan Guitart ◽  
Madeleine Duvic ◽  
Youn H. Kim ◽  
...  

Key Points Lenalidomide is effective in refractory advanced cutaneous T-cell lymphoma, with an overall response rate of 28%. Patients demonstrate a transient flare reaction in skin, blood, and/or lymph nodes that may be associated with improvement in disease burden.


2007 ◽  
Vol 32 (10) ◽  
pp. 1513-1520 ◽  
Author(s):  
Charles A. Goldfarb ◽  
Richard H. Gelberman ◽  
Kathleen McKeon ◽  
Ben Chia ◽  
Martin I. Boyer

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