scholarly journals Transient Neonatal Hypoparathyroidism

2020 ◽  
Author(s):  
Keyword(s):  
Neonatal Hypoparathyroidism

scholarly journals An unusual case of neonatal seizures as manifestation of asymptomatic maternal hypoparathyroidism

2019 ◽  
Vol 12 (8) ◽  
pp. e229160 ◽  
Author(s):  
Pragathi LK ◽  
Raja Kannan P ◽  
Manas Shanbhag
Keyword(s):  
Case Report ◽  
Unusual Case ◽  
Late Onset ◽  
Term Neonate ◽  
Metabolic Status ◽  
Neonatal Seizures ◽  
Birth History ◽  
Normal Birth ◽  
Neonatal Hypoparathyroidism

Neonatal hypoparathyroidism is one of the rare causes of hypocalcaemia. Several cases of neonatal hypoparathyroidism secondary to maternal hyperparathyroidism have been reported. In this case report, we have a term neonate with normal birth history who presented with late onset hypocalcemic seizures. After excluding polyendocrinopathies and related syndromes, hypocalcaemia seizures were secondary to maternal asymptomatic hypoparathyroidism. Since this is one variety of unusual case of maternal and fetal hypoparathyroidism, further testing was mandatory to confirm familial origin. This focuses on the need for every clinician to test maternal metabolic status in case of neonatal manifestations.

Transient neonatal hypoparathyroidism in two siblings unmasking maternal normocalcemic hyperparathyroidism

2007 ◽  
Vol 167 (4) ◽  
pp. 431-434 ◽  
Author(s):  
Preamrudee Poomthavorn ◽  
Boonsong Ongphiphadhanakul ◽  
Pat Mahachoklertwattana
Keyword(s):  
Neonatal Hypoparathyroidism ◽  
Normocalcemic Hyperparathyroidism

Neonatal Hyperparathyroidism and Skeletal Demineralization in an Infant With Familial Hypocalciuric Hypercalcemia

PEDIATRICS ◽  
1993 ◽  
Vol 91 (1) ◽  
pp. 144-145
Author(s):  
BERKLEY R. POWELL ◽  
EUGENE BLANK ◽  
GERDA BENDA ◽  
NEIL R. M. BUIST
Keyword(s):  
Ionized Calcium ◽  
Familial Hypocalciuric Hypercalcemia ◽  
Normal Range ◽  
High Calcium ◽  
Neonatal Hypoparathyroidism

Familial hypocalciuric hypercalcemia (FHH) is a benign dominantly inherited condition, in which the total and ionized calcium are maintained at values well above the normal range.1 When an affected mother is carrying an unaffected fetus, the fetus is chronically exposed to pathologically high calcium levels and neonatal hypoparathyroidism would be expected, as we2 and others have reported.3,4 Conversely, when a fetus is affected, but the mother is not, the fetus might be expected to develop hyperparathyroidism, which should manifest at birth. These infants may require emergency surgery5 or may be managed medically until the hyperparathyroidism subsides.6,7 We report here an infant with FHH, a first cousin of our previous case, who presented with hyperparathyroidism and skeletal demineralization.

Recombinant Parathyroid Hormone Therapy for Severe Neonatal Hypoparathyroidism

2012 ◽  
Vol 160 (2) ◽  
pp. 345-348 ◽  
Author(s):  
Yoon Hi Cho ◽  
Michel Tchan ◽  
Bithi Roy ◽  
Robert Halliday ◽  
Meredith Wilson ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Hormone Therapy ◽  
Neonatal Hypoparathyroidism

scholarly journals Prolonged Transient Neonatal Hypoparathyroidism

1971 ◽  
Vol 64 (7) ◽  
pp. 729-729
Author(s):  
B O'Connell ◽  
Ursula Shelley
Keyword(s):  
Neonatal Hypoparathyroidism

Hypomagnesemia due to two novel TRPM6 mutations

2015 ◽  
Vol 28 (11-12) ◽  
Author(s):  
Michelle Coulter ◽  
Caroline Colvin ◽  
Bruce Korf ◽  
Ludwine Messiaen ◽  
Benjamin Tuanama ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Seizure Activity ◽  
Neonatal Period ◽  
Serum Magnesium ◽  
Magnesium Concentration ◽  
Magnesium Supplementation ◽  
Generalized Seizures ◽  
Neonatal Hypoparathyroidism ◽  
Hispanic Male ◽  
Oral Magnesium

AbstractAlthough most hypocalcemia with hypomagenesemia in the neonatal period is due to transient neonatal hypoparathyroidism, magnesium channel defects should also be considered.We report a case of persistent hypomagnesemia in an 8-day-old Hispanic male who presented with generalized seizures. He was initially found to have hypomagnesemia, hypocalcemia, hyperphosphatemia and normal parathyroid hormone. Serum calcium normalized with administration of calcitriol and calcium carbonate. Serum magnesium improved with oral magnesium sulfate. However, 1 week after magnesium was discontinued, serum magnesium declined to 0.5 mg/dL. Magnesium supplementation was immediately restarted, and periodic seizure activity resolved after serum magnesium concentration was maintained above 0.9 mg/dL. The child was eventually weaned off oral calcium and calcitriol with persistent normocalemia. However, supraphysiologic oral magnesium doses were necessary to prevent seizures and maintain serum magnesium at the low limit of normal.As his clinical presentation suggested primary renal magnesium wastage,Two novel

scholarly journals Hypercalcaemia during pregnancy: Review of maternal and fetal complications, investigations, and management

2018 ◽  
Vol 12 (4) ◽  
pp. 175-179 ◽  
Author(s):  
Jessica Gehlert ◽  
Adam Morton
Keyword(s):  
Primary Hyperparathyroidism ◽  
Serum Calcium ◽  
Pregnancy Complications ◽  
Surgical Intervention ◽  
Retrospective Audit ◽  
Ionised Calcium ◽  
Close Observation ◽  
Fetal Complications ◽  
Mild Primary Hyperparathyroidism ◽  
Neonatal Hypoparathyroidism

Introduction Asymptomatic mild primary hyperparathyroidism is increasingly being identified during pregnancy. Recent studies have demonstrated inconsistent findings with regard to pregnancy complications and the need for surgical intervention during pregnancy. Method A retrospective audit of outcomes of pregnancies complicated by hypercalcaemia over a 15-year period was performed. Results Twenty-nine pregnancies to 26 women with hypercalcaemia were identified, corresponding to 37 cases per 100,000 deliveries. Hypercalcaemia was due to primary hyperparathyroidism in 90% of cases, with mean serum calcium of 2.89 mmol/l and mean ionised calcium 1.43 mmol/l. Four women underwent successful neck exploration during pregnancy. Pregnancy complications were limited to three cases of pre-eclampsia and one case of symptomatic neonatal hypoparathyroidism. Conclusion Close observation without surgical intervention would seem reasonable in women with mild hypercalcaemia during pregnancy.

Neonatal hypoparathyroidism secondary to maternal hypercalcemia

Bone ◽  
2011 ◽  
Vol 49 (6) ◽  
pp. 1379
Author(s):  
G. Viterbo ◽  
C. Tau
Keyword(s):  
Neonatal Hypoparathyroidism
Sign in / Sign up

Export Citation Format

Share Document