scholarly journals Breast Sclerosing Adenosis

2020 ◽  
Author(s):  
Keyword(s):  
2015 ◽  
Vol 467 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Mikinao Oiwa ◽  
Tokiko Endo ◽  
Shu Ichihara ◽  
Suzuko Moritani ◽  
Masaki Hasegawa ◽  
...  

2021 ◽  
Vol 8 (5) ◽  
pp. 1650
Author(s):  
Subhransu Kumar Hota ◽  
Ranjana Giri ◽  
Hardik Kabra ◽  
Devika Chauhan ◽  
Prita Pradhan ◽  
...  

Breast lumps have diverse causes including benign as well as malignant lesions. Fibroadenoma (FA) is a common cause of breast lump. Complex fibroadenomas, a particular subtype, pose diagnostic dilemmas due to confusing the radiological findings and hold higher incidence of transformation to malignancy. A 49 year old female presented with a painless lump in right breast for 2 years which appeared calcified on radiology. Excision biopsy was performed which grossly revealed an encapsulated grey-white firm to hard with cystic areas. Microscopically the sections showed a well encapsulated fibroepithelial tumor showing areas of sclerosing adenosis, hyalinization, cysts lined by cuboidal cells with eosinophilic secretions, areas of calcification and ossification. No evidence of lobular hyperplasia or in-situ carcinoma was seen. Patient was advised follow up. This case represents the unusual occurrence of complex fibroadenoma in a middle-aged female showing with ossification.


Author(s):  
R.E. Mansel ◽  
D.J.T. Webster ◽  
H.M. Sweetland ◽  
L.E. Hughes ◽  
K. Gower-Thomas ◽  
...  

2002 ◽  
Vol 44 (3) ◽  
pp. 232-238 ◽  
Author(s):  
Işıl Günhan-Bilgen ◽  
Ayşenur Memiş ◽  
Esin Emin Üstün ◽  
Necmettin Özdemir ◽  
Yıldız Erhan

2020 ◽  
Vol 181 (1) ◽  
pp. 127-134
Author(s):  
Wei Liu ◽  
Wei Li ◽  
Ziyao Li ◽  
Lei Shi ◽  
Peng Zhao ◽  
...  

Medicine ◽  
2015 ◽  
Vol 94 (49) ◽  
pp. e2298 ◽  
Author(s):  
Naisi Huang ◽  
Jiajian Chen ◽  
Jingyan Xue ◽  
Baohua Yu ◽  
Yanqiong Chen ◽  
...  
Keyword(s):  

Author(s):  
Lilian Wang

Amorphous calcifications are calcifications that are sufficiently small and/or hazy that a more specific morphological classification cannot be made. Historically, such calcifications were referred to as “indistinct” calcifications. The likelihood of malignancy and the management of amorphous calcifications largely depend on their distribution. The majority of amorphous calcifications are benign, most often due to fibrocystic change (60%). Sclerosing adenosis commonly occurs in perimenopausal women and is associated with a 1.5–2.1x relative risk for development of breast cancer. This chapter, appearing in the section on calcifications, reviews the key imaging and clinical features, imaging protocols and pitfalls, differential diagnosis, and management recommendations for amorphous/indistinct calcifications in a regional or diffuse distribution. Topics discussed include influence of distribution on risk of malignancy and pathological entities, including sclerosing adenosis.


2019 ◽  
pp. 205141581984932
Author(s):  
AM Mukendi ◽  
R Blumberg ◽  
G Davies

2019 ◽  
Vol 105 (6) ◽  
pp. NP63-NP66
Author(s):  
Selin Narter ◽  
Secil Hasdemir ◽  
Sahsine Tolunay ◽  
Sehsuvar Gokgoz

Introduction: Sclerosing adenosis is a form of adenosis characterized by lobulocentric architecture, glandular and stromal proliferation in which the stromal component compresses and distorts the glandular structures. Atypical epithelial proliferations such as atypical lobular hyperplasia, lobular carcinoma in situ, and ductal carcinoma in situ may accompany areas of sclerosing adenosis. We present a case of ductal carcinoma in situ and sclerosing adenosis with metastatic carcinoma on sentinel lymph node. Case description: A 40-year-old woman presented with a palpable mass in her left breast. Radiologic studies showed a lesion suggesting malignancy in the left breast and atypical lymph node in the left axillary region. Left lumpectomy and sentinel lymph node biopsy was performed. Histopathologic examination revealed lobulocentric lesions with glandular proliferation and hyalinizing stroma in between. Foci of high-grade cribriform and solid type ductal carcinoma in situ were observed. Sentinel lymph node biopsy showed micrometastasis in one lymph node section. Based on these findings, the patient was diagnosed with high-grade ductal carcinoma in situ with sclerosing adenosis. However, the presence of micrometastasis in the lymph node suggested occult invasion that we were not able to detect. Conclusion: Ductal carcinoma in situ with sclerosing adenosis can mimic invasive carcinoma both radiologically and histologically. It should be kept in mind that there may be occult invasive carcinoma in patients with ductal carcinoma in situ whether the lesion is accompanied by sclerosing adenosis or not. Multiple sections and immunohistochemical studies can be of help.


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