scholarly journals Metastatic Colorectal Mucinous Adenocarcinoma

2020 ◽  
Author(s):  
Keyword(s):  
Mucinous Adenocarcinoma ◽  
Colorectal Mucinous Adenocarcinoma

scholarly journals Clinical significance of signet-ring cells in colorectal mucinous adenocarcinoma

2008 ◽  
Vol 21 (12) ◽  
pp. 1533-1541 ◽  
Author(s):  
Chang Okh Sung ◽  
Jin Won Seo ◽  
Kyoung-Mee Kim ◽  
In-Gu Do ◽  
Seon Woo Kim ◽  
...  
Keyword(s):  
Clinical Significance ◽  
Mucinous Adenocarcinoma ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Colorectal Mucinous Adenocarcinoma

scholarly journals Characteristics and prognostic factors of colorectal mucinous adenocarcinoma with signet ring cells

2017 ◽  
Vol Volume 9 ◽  
pp. 573-580 ◽  
Author(s):  
Xiangquan Kong ◽  
Xueqing Zhang ◽  
Yunxia Huang ◽  
Lirui Tang ◽  
Qingqin Peng ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Mucinous Adenocarcinoma ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Colorectal Mucinous Adenocarcinoma

Clinicopathological characteristics and prognostic factors of advanced colorectal mucinous adenocarcinoma

2012 ◽  
Vol 61 (2) ◽  
pp. 162-169 ◽  
Author(s):  
Tomohiro Yamaguchi ◽  
Hirokazu Taniguchi ◽  
Shin Fujita ◽  
Shigeki Sekine ◽  
Seiichiro Yamamoto ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Mucinous Adenocarcinoma ◽  
Clinicopathological Characteristics ◽  
Colorectal Mucinous Adenocarcinoma

Signet ring cell component predicts aggressive behaviour in colorectal mucinous adenocarcinoma

Pathology ◽  
2019 ◽  
Vol 51 (4) ◽  
pp. 384-391 ◽  
Author(s):  
In Hye Song ◽  
Seung-Mo Hong ◽  
Eunsil Yu ◽  
Yong Sik Yoon ◽  
In Ja Park ◽  
...  
Keyword(s):  
Mucinous Adenocarcinoma ◽  
Aggressive Behaviour ◽  
Signet Ring Cell ◽  
Cell Component ◽  
Signet Ring ◽  
Ring Cell ◽  
Colorectal Mucinous Adenocarcinoma

The expression of THOX2 in colorectal mucinous adenocarcinoma and its relationship with prognosis.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e15529-e15529
Author(s):  
Xue Zhang ◽  
Jing Han ◽  
Zhisong Fan ◽  
Li Feng ◽  
Long Wang ◽  
...  
Keyword(s):  
Lymph Node ◽  
Liver Metastasis ◽  
Lymph Node Metastasis ◽  
Peritoneal Metastasis ◽  
Mucinous Adenocarcinoma ◽  
High Expression ◽  
Clinicopathological Parameters ◽  
Node Metastasis ◽  
Potential Biomarker ◽  
Colorectal Mucinous Adenocarcinoma

e15529 Background: The role of THOX2 in the occurrence and development of tumors has gradually attracted attention, but there is no study on the expression and function of THOX2 in colorectal mucinous adenocarcinoma (MC). The purpose of this study was to investigate the expression of thyroid oxidase 2 (THOX2) in colorectal MC and its relationship with prognosis. Methods: 30 patients with colorectal adenocarcinoma (AC) and 15 patients with MC were selected from The Fourth hospital of Hebei Medical University from October 1, 2018 to July 1, 2019. They were selected to detect the mRNA and protein levels of THOX2 in the colorectal cancer tissues of the two different pathological types using qRT-PCR and immunohistochemistry (IHC) methods. A total of 109 patients with MC who received surgical treatment between January 1, 2015 and January 1, 2015 were selected. The clinicopathological parameters of the patients were collected and survival follow-up was performed. The expression of THOX2 protein in MC tissues was detected by IHC test, and the differences in the expression of THOX2 protein in different tissues were analyzed by χ2 test. Cox univariate and multivariate analyses were used to investigate the relationship between clinicopathological characteristics, THOX2 protein expression level and DFS and OS in patients with MC. Results: The levels of THOX2 mRNA and protein in 15 cases of MC were significantly higher than those in 30 cases of AC. The high expression of THOX2 protein in MC tissues was closely correlated with tumor site, whether mixed with other pathological types, TNM stage, lymph node metastasis, M stage, and liver metastasis, peritoneal metastasis and other site metastasis occurred in patients after initial treatment. Cox regression analysis of 95 patients' survival data showed that high expression of THOX2, right colon and lymph node metastasis were influential factors for DFS in MC patients, and were independent prognostic factors for predicting DFS in MC patients. The expression of THOX2, lymph node metastasis, liver metastasis after adjuvant therapy and peritoneal metastasis are the influencing factors of OS in MC patients. Lymph node metastasis is an independent prognostic factor for OS in MC patients. Conclusions: The expression of THOX2 in MC was significantly higher than that of AC, and it was related to the malignant biological manifestations of tumor. At the same time, the high expression of THOX2 is associated with short DFS and OS in patients with MC, and may be used as a potential biomarker and efficacy predictor for MC patients.

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