scholarly journals Substance Usage Start Date

2020 ◽  
Author(s):  
Keyword(s):  
Start Date

A DEFINITIVE 6 MA START DATE FOR CARVING OF THE NORTHEASTERN COLORADO PLATEAU CANYONLANDS

2016 ◽  
Author(s):  
Stuart N. Thomson ◽  
◽  
Gerilyn S. Soreghan ◽  
Peter W. Reiners ◽  
Kendra E. Murray ◽  
...  
Keyword(s):  
Colorado Plateau ◽  
Start Date

scholarly journals Reproductive Performance and Partial Budget Analysis of a Prostaglandin or a Modified Ovsyn3ch Protocol in Autumn Calving Dairy Herds

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1031
Author(s):  
George Lindley ◽  
Jim Willshire ◽  
Steven Van Winden
Keyword(s):  
Relative Effectiveness ◽  
Dairy Herds ◽  
Net Benefit ◽  
Start Date ◽  
Budget Analysis ◽  
Partial Budget ◽  
Holstein Friesian ◽  
Input Variables ◽  
Input Uncertainties ◽  
Relative Profitability

In autumn calving dairy herds, treatment of cattle not observed in estrus prior to the breeding season is common. Routinely, a single prostaglandin or a modified Ovsynch (MOFT) protocol are used—without evidence of their relative effectiveness. This study compares the effects on conception, associated timing, and profitability of administering cows with prostaglandin or MOFT treatment. A hundred and ninety-two Holstein-Friesian cows from three herds without an observed estrus within 28-days before mating start date were randomly treated with d-cloprostenol (PGOD) or an 8-day MOFT protocol. The association of treatment and calving-breeding start-date interval (CBSI) on the risk of conception were investigated. Partial budget, sensitivity analysis, and Monte Carlo simulation was used to assess economic performance, identify critical input variables, and explore the effects of input uncertainties on model output. There was a significant association between MOFT treatment and conception during 21 and 84 days after mating start date, compared to PGOD. MOFT treatment was associated with a mean net benefit of £58.21 (sd £19.42) and £27.29 (sd £17.75) per cow for herds with a fixed or variable dry-off date, respectively. The relative profitability of an MOFT protocol is dependent on its effects on barren rate and herd dry-off strategy.

scholarly journals Variation in Measures of Antimicrobial Use Across Four Nursing Homes, Atlanta, Georgia, 2019

2020 ◽  
Vol 41 (S1) ◽  
pp. s510-s510
Author(s):  
William Dube ◽  
Sahebi Saiyed ◽  
Patricia Comer ◽  
Michael Hanichen ◽  
Christie Klinczar ◽  
...  
Keyword(s):  
Nursing Homes ◽  
Antibiotic Stewardship ◽  
Respiratory Infections ◽  
Local Treatment ◽  
Treatment Guideline ◽  
Transitions Of Care ◽  
Term Care ◽  
Start Date ◽  
Treatment Site ◽  
Days Of Therapy

Background: Although antibiotic stewardship programs (ASP) are now required in nursing homes, assimilating and responding to data to improve prescribing in nursing homes is novel. Four Atlanta-based skilled nursing facilities (SNFs) began collaborating (EASIL: Emory Antibiotic Stewardship in Long-Term Care) to share standardized prescribing data to allow interfacility comparisons and action. Methods: After SNF ASPs were evaluated and trained, standardized prescribing logs were submitted (January 2019 to June 2019) including the following data: start date, treatment site, prescriber attribution of order (ie, SNF order vs hospital order) and monthly resident days. SNF-specific point estimates of usage rates were calculated as pooled means for all antibiotic starts, SNF-order starts, and days of therapy (DOT), by treatment site per 1,000 resident days. Duration of urinary tract infection (UTI) therapy was assessed by calculating percentage of SNF-UTI starts over recommended duration defined by the local treatment guideline. Rate ratios (RRs) of use were calculated to compare SNF-specific rates to the largest SNF. The 95% CIs were calculated using normal approximation. Results: Monthly starts ranged from 124 to 177, with a pooled mean of 7.8 antibiotic starts (any type), 4.5 SNF-order starts, and 1.2 SNF-UTI starts per 1,000 resident days. Approximately half of all starts were SNF starts (range, 43%–53%), and less than half of DOT were attributed to SNF starts (range, 35%–45%). Overall, SNF-order treatment sites were most often UTIs (29%), lower respiratory infections (17%), and skin and soft-tissue infections (17%). SNF-order UTI starts per 1,000 patient days varied at 1 SNF (SNF B RR, 1.57; 95% CI, 1.04–2.36). SNF-order UTI DOT per 1,000 patient days was more variable, with SNFs B and C having significantly higher rates (B RR, 1.49, 1.24, and 1.82; C RR, 5.42; 95% CI, 4.65–6.34) than SNF A (Fig. 1). The percentage of SNF-order UTI starts that were over recommended duration ranged from 8% (nitrofurantoin, SNF A) to 100% (fluoroquinolones, SNF C) (Fig. 1). Conclusions: Although UTIs are the single most common reason to prescribe antibiotics after arriving in a SNF, they account for a small fraction of overall starts and an even smaller fraction of DOT. We identified outlier prescribing by different SNFs using 3 metrics, suggesting that distinct corrective actions are necessary to target distinct prescribing challenges (starts, duration, and transitions of care).Funding: NoneDisclosures: Scott Fridkin reports that his spouse receives consulting fees from the vaccine industry.

scholarly journals The Acceptability, Feasibility and Effectiveness of Wearable Activity Trackers for Increasing Physical Activity in Children and Adolescents: A Systematic Review

2021 ◽  
Vol 18 (12) ◽  
pp. 6211
Author(s):  
Amy V. Creaser ◽  
Stacy A. Clemes ◽  
Silvia Costa ◽  
Jennifer Hall ◽  
Nicola D. Ridgers ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Children And Adolescents ◽  
Behaviour Change Techniques ◽  
Physically Active ◽  
Self Monitoring ◽  
Start Date ◽  
Activity Trackers ◽  
Wearable Activity Trackers

Wearable activity trackers (wearables) embed numerous behaviour change techniques (BCTs) that have previously been shown to increase adult physical activity (PA). With few children and adolescents achieving PA guidelines, it is crucial to explore ways to increase their PA. This systematic review examined the acceptability, feasibility, and effectiveness of wearables and their potential mechanisms of action for increasing PA in 5 to 19-year-olds. A systematic search of six databases was conducted, including data from the start date of each database to December 2019 (PROSPERO registration: CRD42020164506). Thirty-three studies were included. Most studies (70%) included only adolescents (10 to 19 years). There was some—but largely mixed—evidence that wearables increase steps and moderate-to-vigorous-intensity PA and reduce sedentary behaviour. There were no apparent differences in effectiveness based on the number of BCTs used and between studies using a wearable alone or as part of a multi-component intervention. Qualitative findings suggested wearables increased motivation to be physically active via self-monitoring, goal setting, feedback, and competition. However, children and adolescents reported technical difficulties and a novelty effect when using wearables, which may impact wearables’ long-term use. More rigorous and long-term studies investigating the acceptability, feasibility, and effectiveness of wearables in 5 to 19-year-olds are warranted.

scholarly journals Methods for the Quantification of Resistance of Apple Genotypes to European Fruit Tree Canker Caused by Neonectria ditissima

Plant Disease ◽  
2017 ◽  
Vol 101 (12) ◽  
pp. 2012-2019 ◽  
Author(s):  
M. Wenneker ◽  
P. W. Goedhart ◽  
P. van der Steeg ◽  
W. E. van de Weg ◽  
H. J. Schouten
Keyword(s):  
Statistical Significance ◽  
Lesion Size ◽  
Fruit Tree ◽  
Infection Frequency ◽  
Pome Fruit ◽  
Start Date ◽  
Apple Cultivars ◽  
Lesion Growth ◽  
Two Parameters ◽  
Parallel Tests

European fruit tree canker, caused by Neonectria ditissima, is an important disease of pome fruit worldwide. Apple cultivars differ in their levels of susceptibility to N. ditissima. In order to design an effective plant resistance test, we examined the effectiveness of two resistance parameters: infection frequency and lesion growth. Both parameters were evaluated in parallel tests using 10 apple cultivars in three experimental years, applying seminatural infection of leaf scars (infection frequency) or inoculation of artificial wounds (lesion growth). We compared six parameters for lesion growth, of which a new parameter, lesion growth rate (LGR), appeared to be the best with respect to reproducibility and statistical significance. LGR is defined as the slope of the regression of lesion size versus time. The slope was estimated for each lesion, employing a common start date and a lesion-specific end date determined by the girdling of the lesion. The two parameters (infection frequency and LGR) were examined in separate experiments and in three successive years, and provided complementary information and resulted in reproducible conclusions on the relative resistance levels to N. ditissima of the tested cultivars. The presented methods can be used to develop strategies for the control of European fruit tree canker (e.g., in the breeding of new apple cultivars with high levels of resistance to N. ditissima).

Phenological phases of pollination related to climate change

2021 ◽  
Author(s):  
Samuel Monnier ◽  
Michel Thibaudon ◽  
Jean-Pierre Besancenot ◽  
Charlotte Sindt ◽  
Gilles Oliver
Keyword(s):  
Climate Change ◽  
Pollen Season ◽  
Microscopic Analysis ◽  
Allergic Diseases ◽  
Early Spring ◽  
Late Winter ◽  
General Tendency ◽  
New Production ◽  
Start Date ◽  
Generic Term

<p>Knowledge:</p><p>Rising CO2 levels and climate change may be resulting in some shift in the geographical range of certain plant species, as well as in increased rate of photosynthesis. Many plants respond accordingly with increased growth and reproduction and possibly greater pollen yields, that could affect allergic diseases among other things.</p><p>The aim of this study is the evolution of aerobiological measurements in France for 25-30 years. This allows to follow the main phenological parameters in connection with the pollination and the ensuing allergy risk.</p><p>Material and method:</p><p>The RNSA (French Aerobiology Network) has pollen background-traps located in more than 60 towns throughout France. These traps are volumetric Hirst models making it possible to obtain impacted strips for microscopic analysis by trained operators. The main taxa studied here are birch, grasses and ragweed for a long period of more than 25 years over some cities of France.</p><p>Results:</p><p>Concerning birch but also other catkins or buds’ trees pollinating in late winter or spring, it can be seen an overall advance of the pollen season start date until 2004 and then a progressive delay, the current date being nearly the same as it was 20 years ago, and an increasing trend in the quantities of pollen emitted.</p><p>For grasses and ragweed, we only found a few minor changes in the start date but a longer duration of the pollen season.</p><p>Discussion:</p><p>As regards the trees, the start date of the new production of catkins or buds is never the 1<sup>st</sup> of January but depends on the species. For example, it is early July for birch. For breaking dormancy, flowering, and pollinating, the trees and other perennial species need a period of accumulation of cold degrees (Chilling) and later an accumulation of warm degrees (Forcing). With climate change these periods may be shorter or longer depending of the autumn and winter temperature. Therefore, a change in the annual temperature may have a direct effect on the vegetal physiology and hence on pollen release. It may also explain why the quantities of pollen produced are increasing.</p><p>The Poaceae reserve, from one place to another and without any spatial structuring, very contrasted patterns which make it impossible to identify a general tendency. This is probably due to the great diversity of taxa grouped under the generic term Poaceae, which are clearly not equally sensitive to climate change.</p><p>Conclusion:</p><p>Trees with allergenic pollen blowing late winter or early spring pollinate since 2004 later and produce amounts of pollen constantly increasing. Grasses and ragweed have longer periods of pollination with either slightly higher or most often lower pollen production.</p>

scholarly journals ECDC management board elects chair and deputy following international startup event in Stockholm

2004 ◽  
Vol 8 (40) ◽  
Author(s):  
Keyword(s):  
European Union ◽  
Disease Prevention ◽  
Prevention And Control ◽  
Management Board ◽  
Start Date ◽  
European Centre ◽  
And Control

A startup event was held for the new European Union agency, the European Centre for Disease Prevention and Control, in Stockholm on 27 September, in preparation for the operational start date of May 2005

scholarly journals Association Between BCG Policy is Significantly Confounded by Age and is Unlikely to Alter Infection or Mortality Rates

2020 ◽  
Author(s):  
Stefan Kirov
Keyword(s):  
Mortality Rates ◽  
Causal Link ◽  
Confounding Factors ◽  
Income Levels ◽  
Bcg Vaccination ◽  
Start Date ◽  
The Press ◽  
Number Of Publications ◽  
Public Policy Decisions ◽  
Mandatory Vaccination

AbstractRecently a number of publications looked at the association between COVID-19 morbidity and mortality on one hand and countries’ policies with respect to BCG vaccination on the other. This connection arises from differences in the rates of infection in countries where BCG vaccination is mandatory compared to countries where mandatory vaccination no longer exists or was never implemented in the first place. In at least 2 preprint publications the authors expressed the view that the “known immunological benefits” of BCG vaccination may be behind the biological mechanism of such observation.One study accounted for different income levels in different groups. Another study did not attempted to do so, instead exploring the differences between countries where a booster shot is given vs others where no such practice exists (finding no connection).Both of these studies did not explore other potential confounding factors. Meanwhile the press has focused on these headlines and pushed the narrative that BCG vaccination is causally linked to infection and mortality rates. This poses a serious challenge, demonstrated by the recently initiated clinical trials on BCG vaccination within the COVID19 context.This study shows that population age is a very significant confounding factor that explains the rates of infections much better and has a solid biology mechanism which explains this correlation. It suggests that BCG vaccination may have little or no causal link to infection rates and advises that any follow up studies should control for several confounding factors, such as population age, ethnicity, rates of certain chronic diseases, time from community spread start date, major public policy decisions and income levels.

scholarly journals Mugwort pollen season in the air of Poland in 2019

Alergoprofil ◽  
2019 ◽  
Vol 15 (4) ◽  
pp. 23-28
Author(s):  
Małgorzata Puc ◽  
Piotr Rapiejko ◽  
Agnieszka Lipiec ◽  
Małgorzata Malkiewicz ◽  
Katarzyna Dąbrowska-Zapart ◽  
...  
Keyword(s):  
Pollen Season ◽  
Pollen Grains ◽  
Start Date ◽  
Airborne Concentration ◽  
Pollen Concentrations ◽  
Artemisia Species ◽  
Pollen Seasons ◽  
June July ◽  
Artemisia Pollen ◽  
Seasonal Pollen

  The Asteraceae family is one of the largest families, comprising 67 genera and 264 species in Poland. However, only a few genera, including Artemisia, are potential allergenic sources. The aim of the study was to compare the mugwort pollen seasons in Bialystok, Bydgoszcz, Sosnowiec, Lublin, Piotrkow Trybunalski, Opole, Olsztyn, Szczecin, Warsaw and Wroclaw in 2019. The investigations were carried out using the volumetric method. Seasonal Pollen Index was estimated as the sum of daily average pollen concentrations in the given season. The mugwort pollen season is mainly observed in June, July and at the beginning of September. In 2019 the pollen season of mugwort started first in Opole, on the June 26th. At the latest, a pollen season ended in Bydgoszcz and Warsaw, at the end of September. The differences of pollen seasons duration were extremely considerable, from 35 to 83 days. The highest airborne concentration of 97 pollen grains/m3 was noted in Lublin on the July 31st. The maximum values of seasonal pollen count in Polish cities occurred between July 28th and August 12th, most often between in late July and early August. The highest mugwort pollen allergen hazard occurred in 2019 in Lublin, Warsaw, Opole and Wroclaw, and was 2–3 times higher than in other cities. The highest variability in the analysed seasons was found in start date, while the lowest in the peak value and SPI value. In the pollen season in 2019, 2 peaks of Artemisia pollen concentrations were observed as a result of the order of flowering of A. vulgaris and A. campestris. Information on the pollination of various Artemisia species will be used to avoid excessive exposure to allergens of these pollen grains.

Sign in / Sign up

Export Citation Format

Share Document