scholarly journals Atypical Adenoma

2020 ◽  
Author(s):  
Keyword(s):  
Atypical Adenoma

Molecular status of pituitary carcinoma and atypical adenoma that contributes the effectiveness of temozolomide

2013 ◽  
Vol 47 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Akira Matsuno ◽  
Mineko Murakami ◽  
Katsumi Hoya ◽  
Shoko M. Yamada ◽  
Shinya Miyamoto ◽  
...  
Keyword(s):  
Pituitary Carcinoma ◽  
Atypical Adenoma

scholarly journals Atypical adenoma of the thyroid diagnosed as anaplastic cancer by cytopathology

2017 ◽  
Vol 45 (10) ◽  
pp. 928-933
Author(s):  
Hiromitsu Hatakeyama ◽  
Kimiko Hoshino ◽  
Kenji Mizoguchi ◽  
Takayoshi Suzuki ◽  
Kanako C. Hatanaka ◽  
...  
Keyword(s):  
Atypical Adenoma

Two cases of atypical adenoma of the thyroid-Is atypical adenoma of the thyroid a true benign lesion?-

2010 ◽  
Vol 49 (3) ◽  
pp. 190-195 ◽  
Author(s):  
Mitsuhiro TACHIBANA ◽  
Yumi HASHIMOTO ◽  
Tamae SONE ◽  
Naoki OOISHI ◽  
Tatsuo UENO ◽  
...  
Keyword(s):  
Benign Lesion ◽  
Atypical Adenoma

Robotic-assisted transaxillary parathyroidectomy of an atypical adenoma

2011 ◽  
Vol 21 (3) ◽  
pp. 201-205 ◽  
Author(s):  
Leah Katz ◽  
Mohamed Abdel Khalek ◽  
Byron Crawford ◽  
Emad Kandil
Keyword(s):  
Robotic Assisted ◽  
Atypical Adenoma

scholarly journals Parathyroid Carcinoma: The Importance of High Clinical Suspicion for a Correct Management

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Gabriele Ricci ◽  
Marco Assenza ◽  
Marco Barreca ◽  
Gianluca Liotta ◽  
Livio Paganelli ◽  
...  
Keyword(s):  
Parathyroid Carcinoma ◽  
Central Compartment ◽  
Complete Resection ◽  
Clinical Suspicion ◽  
Initial Operation ◽  
En Bloc ◽  
Atypical Adenoma ◽  
Lung Lobectomy ◽  
High Clinical Suspicion ◽  
Secondary Referral Hospital

Background. Parathyroid carcinoma is an infrequent clinical entity whose diagnosis is very challenge. Indeed a pre-operative or intraoperative diagnosis of parathyroid carcinoma is reported in less than half cases described in the literature.Patients and Methods. A systematic review of pathological reports of our secondary referral hospital was done. From 2003 to 2011 one hundred and forty-four patients were operated for hyperparathyroidism. One patient with atypical adenoma and three patients with parathyroid carcinoma were included in this paper.Results. Anen blocresection of the tumor was performed in three patients. Two of this patients with diagnosis of parathyroid carcinoma are alive with no evidence of recurrence or metastasis, respectively, 48 and 60 months after the operation; one patient with diagnosis of atypical adenoma died for other disease 16 months after the operation. In the last patient a simple parathyroidectomy was performed. After that histology revealed the diagnosis of parathyroid carcinoma the patient underwent reoperation for left hemithyroidectomy and central compartment lymph node clearance. After 30 months a lung lobectomy was done due to metastasis.Conclusion. Parathyroid carcinoma should be considered in the differential diagnosis of PTH-dependent hypercalcemia because optional outcomes are associated with complete resection of the tumor at the time of initial operation.

The Past, Present, and Future Statuses of Formerly Classified “Atypical Pituitary Adenomas”: A Clinicopathological Assessment of 101 Cases in a Cohort of More than 1,000 Pure Endoscopically Treated Patients in Single Center

2020 ◽  
Author(s):  
Ercan Bal ◽  
İbrahim Kulaç ◽  
Selim Ayhan ◽  
Figen Söylemezoğlu ◽  
Mustafa Berker
Keyword(s):  
Pituitary Adenomas ◽  
Labeling Index ◽  
World Health ◽  
Pituitary Neoplasms ◽  
Ki 67 ◽  
Cavernous Sinus Invasion ◽  
Atypical Adenoma ◽  
Endocrine Organs ◽  
Significant Difference ◽  
Cure Rates

Abstract Aim This study was aimed to assess the clinical aggressiveness of pituitary neoplasms that were previously defined as atypical adenomas. Methods A total of 1,042 pituitary adenomas were included in the study and 101 of them were diagnosed as atypical adenoma. Demographic characteristics, radiological evaluations, and clinical information were obtained from a computer-based patient database. Cases were categorized as atypical or typical using the criteria listed in 2004 Classification of Tumors of Endocrine Organs. Results The cure and reoperation rates did not show any statistically significant difference between the typical and atypical adenomas. However, a higher Ki-67 labeling index was found to be associated with a higher rate of reoperation (p = 0.008) in atypical adenomas. Of note, cavernous sinus invasion or parasellar extension was found to be associated with lower cure rates in patients with atypical pituitary adenomas (p < 0.001 and p = 0.001, respectively). Conclusion Although atypical pituitary adenomas are known to be more invasive, this study demonstrated that the reoperation and cure rates are the same for typical and atypical adenomas. Our findings advocate for omitting the use of atypical adenoma terminology based solely on pathological evaluation. As stated in the 4th edition of the World Health Organization (WHO) classification, accurate tumor subtyping, evaluation of proliferation by means of mitotic count and Ki-67 labeling index, and radiological and intraoperative assessments of tumor invasion should be taken into consideration in the management of such neoplasms.

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