Chronic Lymphadenitis

2020 ◽  
Author(s):  
Keyword(s):  
Chronic Lymphadenitis

scholarly journals Husband and wife with sarcoidosis: possible environmental factors involved

2013 ◽  
Vol 8 ◽  
Author(s):  
Ilaria Leli ◽  
Ivano Salimbene ◽  
Francesco Varone ◽  
Leonello Fuso ◽  
Salvatore Valente
Keyword(s):  
Case Report ◽  
Environmental Factors ◽  
Lymph Node Biopsy ◽  
Host Factors ◽  
Multisystem Disorder ◽  
Node Biopsy ◽  
Etiologic Agents ◽  
Unclear Etiology ◽  
Genetically Determined ◽  
Chronic Lymphadenitis

Sarcoidosis is a granulomatous multisystem disorder of unclear etiology that involves any organ, most commonly the lung and the lymph nodes. It is hypothesized that the disease derives from the interaction between single or multiple environmental factors and genetically determined host factors. Multiple potential etiologic agents for sarcoidosis have been proposed without any definitive demonstration of causality. We report the case of two patients, husband (57 years old) and wife (55 years old), both suffering from sarcoidosis. They underwent a lymph node biopsy by mediastinoscopy which showed a “granulomatous epithelioid giant cell non-necrotising chronic lymphadenitis”. They had lived up to 3 years ago in the country in a farm, in contact with organic dusts, animals such as dogs, chickens, rabbits, pigeons; now they have lived since about 3 years in an urban area where there are numerous chemical industries and stone quarries. The aim of this case report was to focus on environmental factors that might be related to the pathogenesis of the sarcoidosis.

Phenotypic difference of normal plasma cells from mature myeloma cells

Blood ◽  
1993 ◽  
Vol 81 (10) ◽  
pp. 2658-2663 ◽  
Author(s):  
H Harada ◽  
MM Kawano ◽  
N Huang ◽  
Y Harada ◽  
K Iwato ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Fluorescein Isothiocyanate ◽  
Color Analysis ◽  
Phenotypic Difference ◽  
Phenotypic Analysis ◽  
Color Flow ◽  
Myeloma Cells ◽  
Normal Plasma ◽  
Healthy Donors ◽  
Chronic Lymphadenitis

We have recently shown that two-color analysis with fluorescein isothiocyanate (FITC)-anti-CD38 antibody could clearly distinguish myeloma cells (plasma cells) from other hematopoietic cells in the bone marrow. Myeloma cells (plasma cells) alone were located at CD38strong positive (++) fractions. To further distinguish normal plasma cells from mature myeloma cells phenotypically, we examined immunophenotypes of normal plasma cells and myeloma cells by two-color flow cytometry with FITC-anti-CD38 antibody and phycoerythrin staining with antibody to VLA-4, MPC-1, CD44, CD56, CD19, CD20, CD24, or CD10. Normal plasma cells were all VLA-4+VLA-5+MPC-1+CD44+ CD19+CD56- in the bone marrows from seven healthy donors, tonsils from four patients with chronic tonsillitis, a spleen from one patient with idiopathic thrombocytopenic purpura, and lymph nodes from two patients with chronic lymphadenitis, respectively. On the other hand, mature myeloma cells (12 of 20 cases), VLA-4+VLA-5+MPC-1+, were all CD19- and most of them CD56+, and there were no myeloma cells with the CD19+CD56- phenotype in the 20 cases of myelomas we tested. Thus, as for the expression of CD19 and CD56, normal plasma cells from various tissues are all CD19+CD56-, whereas no myeloma cells have the CD19+CD56- phenotype. According to this finding, we investigated the expression of CD19 and CD56 on plasma cells (CD38++ fractions) in monoclonal gammopathy of undetermined significance (MGUS). Both CD19+CD56- and CD19-DC56+ plasma cells were found in all five cases of MGUS we tested, suggesting that MGUS consists of phenotypically normal plasma cells and myeloma cells. Therefore, it is reasoned that phenotypic analysis of plasma cells with anti-CD19 and anti-CD56 antibodies can distinguish normal plasma cells from malignant plasma cells (myeloma cells), and can detect malignant plasma cells even in MGUS or premyeloma states.

Mycobacterium interjectum, a new species isolated from a patient with chronic lymphadenitis.

1993 ◽  
Vol 31 (12) ◽  
pp. 3083-3089 ◽  
Author(s):  
B Springer ◽  
P Kirschner ◽  
G Rost-Meyer ◽  
K H Schröder ◽  
R M Kroppenstedt ◽  
...  
Keyword(s):  
New Species ◽  
Chronic Lymphadenitis ◽  
A New Species

scholarly journals Cutaneous lymphoma misdiagnosed as chronic lymphadenitis

2015 ◽  
Vol 13 (6) ◽  
pp. 1227-1230
Author(s):  
Mircea Munteanu ◽  
Georgiana S Mohor ◽  
Flavia Baderca ◽  
Caius Solovan
Keyword(s):  
Cutaneous Lymphoma ◽  
Chronic Lymphadenitis

scholarly journals Immunocytochemical Expression of IFN-γ and IL-4 in Tuberculous Lymphadenitis with Dark Oval Bodies

2020 ◽  
Vol 8 (A) ◽  
pp. 806-809
Author(s):  
Humairah Medina Liza Lubis ◽  
Ratna Akbari Ganie ◽  
Delyuzar Delyuzar ◽  
Putri Chairani Eyanoer ◽  
Delfitri Munir
Keyword(s):  
Antigen Expression ◽  
Tuberculous Lymphadenitis ◽  
Exact Tests ◽  
Ifn Γ ◽  
Chronic Lymphadenitis

BACKGROUND: We noticed some smears being cytologically diagnosed as common chronic lymphadenitis that cannot be treated with ordinary antibiotics, but succeeded with the anti-tuberculosis drug (ATD), even though it takes longer, up to a year or more. Re-examining the MGG smears, we got cases that show the structure, we call Dark Oval Bodies (DOB). Most of DOB smears express Interferon (IFN)-γ. IFN-γ _plays a role in the protection of infection while interleukin (IL)-4 in the opposite. AIM: The purpose of this study is to determine if there is a difference between an expression of IFN-γ _and IL-4 in DOB and whether IFN-γ _is associated with the protection of the disease. MATERIALS AND METHODS: Included in this study 41 cases of tuberculous lymphadenopathy with DOB that were not successfully treated with common antibiotics but succeeded with ATD. Antigen expression was determined using rabbit polyclonal to IFN-γ, (ab9657), and IL-4 (ab9622), Abcam. The expression was categorized as positive and negative. The details of the 41 cases were 37 cases (90%) with IFN-γ _(+), 4 (10%) with IFN-γ _(-), 10 (24%) with IL-4 (+), and 31 (76%) with IL-4 (-). Thirty cases expressed IFN-γ _(+) and IL-4 (-), 1: IFN-γ _(-) and IL-4 (+), 8: IFN-γ _(+) and IL-4 (+), and 2: IFN-γ _(-) and IL-4 (-). RESULTS: IFN-γ _is more frequently expressed in DOB compared to IL-4 (p<0.05, the Fisher’s exact tests). CONCLUSION: IFN-γ _can be benefited as the indicator of protection to the tuberculous process.

scholarly journals ELECTRON MICROSCOPIC OBSERVATIONS ON CHRONIC LYMPHADENITIS IN THE SUBMUCOSA

1973 ◽  
Vol 20 (1) ◽  
pp. 25-33
Author(s):  
TAMAKA OKINA ◽  
SHIGEYASU JINNOUCHI ◽  
HIDEZIRO INOUE ◽  
MASAO YAMAMOTO ◽  
YOUSUKE KITAHARA
Keyword(s):  
Electron Microscopic ◽  
Chronic Lymphadenitis

Acute and Chronic Lymphadenitis

2020 ◽  
pp. 15-20
Author(s):  
Joseph Domachowske ◽  
Manika Suryadevara
Keyword(s):  
Chronic Lymphadenitis

Tl-201 Uptake in Chronic Lymphadenitis

2000 ◽  
Vol 25 (11) ◽  
pp. 943
Author(s):  
HITOYA OHTA ◽  
MASAYUKI SHINTAKU
Keyword(s):  
Chronic Lymphadenitis

scholarly journals GIANT CELLS IN CULTURES FROM HUMAN LYMPH NODES

1921 ◽  
Vol 33 (3) ◽  
pp. 349-360 ◽  
Author(s):  
Warren H. Lewis ◽  
Leslie T. Webster
Keyword(s):  
Lymph Nodes ◽  
Central Area ◽  
Giant Cells ◽  
Neutral Red ◽  
The Other ◽  
Waste Products ◽  
Fat Globules ◽  
Dead Material ◽  
Chronic Lymphadenitis ◽  
Metastatic Sarcoma

Giant cells resembling those found in tuberculous nodes appeared in cultures of various normal and pathological human lymph nodes cultivated in plasma. They migrated out from the explants from normal and tuberculous nodes, from nodes from acute and chronic lymphadenitis and Hodgkin's disease, and from a metastatic sarcoma. They were most abundant in cultures from tuberculous nodes. The giant cells are similar in structure to the large wandering cells and probably arise from them. We are uncertain, however, as to how the giant cells develop. There is no evidence of fusion of the large mononuclear wandering cells; on the other hand, there is some evidence that they arise by amitosis of the nuclei without division of the cytoplasm, which increases in bulk. They contain a large central area of more or less granular character which takes up neutral red with great avidity. This central area probably consists of dead material, the waste products of metabolism and of digested foodstuffs such as lymphocytes that the cells are unable to get rid of in the abnormal environment, and perhaps also of accumulated non-living foreign substances that have penetrated into the cells and become segregated. The central area is surrounded by a conspicuous zone of fat globules in which the nuclei are embedded. The nuclei vary in number from 2 or 3 to 50 or 60. Usually, however, there are not more than 10 or 20, and in the cells that are flattened out on the cover-slip they often have a horseshoe-like arrangement about the equator of the central area. Mitochondria are abundant and usually in the form of wavy or curly threads. They seem to be most numerous in the ectoplasm immediately about the fat zone. They also extend in among the fat globules and out into the ectoplasm. A distinct, clear, homogeneous ectoplasm envelops the cell.

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