scholarly journals Lymph Node Capsule

2020 ◽  
Author(s):  
2011 ◽  
Vol 151 (1) ◽  
pp. 5-8 ◽  
Author(s):  
G. I. Lobov ◽  
M. N. Pan’kova

1977 ◽  
Vol 1 (6) ◽  
pp. 451-461 ◽  
Author(s):  
J. G. AZZOPARDI ◽  
C. M. D. ROSS ◽  
G. FRIZZERA

1984 ◽  
Vol 10 (8) ◽  
pp. 596-598 ◽  
Author(s):  
P. MASCI ◽  
A. CIARDI ◽  
U. DI TONDO

1969 ◽  
Vol 55 (6) ◽  
pp. 371-386 ◽  
Author(s):  
Roberto Molinari ◽  
Lorenzo Zingo

In 1080 patients operated on at the National Cancer Institute of Milan from 1937 to 1964, 84 recurrences appeared on the operative field after radical neck dissection for oropharyngeal cancer. There was no evidence of the primary tumor almost 2 years after treatment. 78 recurrences concerned 930 determined cases (8.9%): 7 appeared among 407 dissections in which no microscopic involvement of lymph nodes was demonstrated (1.72%); 77 among 673 operations for histologically positive nodes. Most recurrences (75/84) were localized in the upper regions of the operative field (upper carotid, retromandibular, submastoid area). In all but 3 cases they occurred in the region nearest to the primary. Clinically, recurrences appeared as isolated or multiple tumor nodes adherent to the skin or to deep structures or both; only in 7 cases they were movable, and among these 5 were external to the operative field. Histological examination of the node was performed in 35 cases; residual lymph node tissue was found only in the movable ones. In nearly all cases isolated « foci» were found, and these findings suggest a sowing of cancer cells. Pathogenesis of recurrences is discussed, and the conclusions are that: — In 50% of cases cancer cells spread out actively from the walls of the lymph node by an invasive mechanism; — In 40% of cases sowing was due to the surgical section of lymph vessels or, rarely, of the lymph node capsule; — In 2.7% of cases the recurrence was localized in lymph nodes not removed at surgery; — In 4.7% of cases the typical dissection was not sufficiently extensive, and recurrences can appear outside the operative field, often in the parotid gland, very seldom in the spinal chain. Since the therapy of cervical recurrences is very deceptive prognosis can be improved only by preventing them, and this can be attained by earlier operations (prophylactic dissections) and surgical refinements in technique and tactics.


2021 ◽  
Vol 84 (4) ◽  
pp. 607-617
Author(s):  
A.K. Kayapinar ◽  
D Solakoglu ◽  
K Bas ◽  
E Oymaci ◽  
B Isbilen ◽  
...  

Background and study aims: The prognostic value of H. pylori, which infects more than half of the human population living in the world and plays a role in gastric cancer pathogenesis, is controversial. Our aim is to investigate the relationship between H. pylori and prognostic factors in gastric cancer. Patients and methods: The data of 110 patients (38 females and 72 males) that underwent surgeries due to gastric cancer between 2014 and 2017 were retrospectively analyzed. The relationships between survival (disease-free and overall) and factors such as p53, HER2/neu, Ki-67, neutrophil and platelet lymphocyte ratio (NLR / PLR), histopathological and demographic characteristics were examined. In addition, the results of H. pylori positive and negative groups were compared. Results: Sixty-one (55%) patients were H. pylori negative and 49 (45%) were positive. In multivariate analysis, TNM stage, lymph node capsule invasion and NLR were determined as independent prognostic factors in both disease-free and overall survival. Age>62 and PLR>14.3 were determined as independent predictive factors of poor prognosis in overall survival. In univariate analysis, tumor diameter of >4.3 cm, lymphovascular and perineural invasion, and diffuse p53 expression were determined as predictive factors of poor prognosis in disease-free and overall survival. The effectiveness of these markers in prognosis was not different between H. pylori negative and positive groups. Conclusion: While age, tumor diameter, TNM stage, lymph node capsule invasion, perineural and lymphovascular invasion, diffuse p53, PLR, and NLR were determined as prognostic factors in gastric cancer, these factors were not affected by the presence of H. pylori.


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