scholarly journals Cytoplasmic Vacuolation

2020 ◽  
Author(s):  
Keyword(s):  
Cytoplasmic Vacuolation

Ultrastructural diagnosis of plasmacytoma on a fine-needle aspirate

1991 ◽  
Vol 49 ◽  
pp. 102-103
Author(s):  
S. Siew ◽  
W. deMendonca-Calaca
Keyword(s):  
Mononuclear Cells ◽  
Fibrous Tissue ◽  
Needle Aspiration ◽  
Focal Lesions ◽  
Diffuse Infiltration ◽  
Fine Needle ◽  
Cytoplasmic Vacuolation ◽  
Chest Mass ◽  
Mitotic Figures ◽  
Microscopy Examination

A 36 year old man presented with a mass in the chest and multiple “hot” focal lesions were identified on bone scan. Fine needle aspiration was performed of the chest mass. Routine histology showed the presence of some bundles of dense fibrous tissue and a diffuse infiltration of mononuclear cells, which varied in size and nucleo-cytoplasmic ratio. The smaller cells had eccentric hyperchromatic nuclei. Nucleoli were noted in the larger cells. There was well marked cytoplasmic vacuolation of some of the cells. Mitosis was present. A small fragment of tissue was received for electron microscopy. Examination of 1 μm sections showed trabeculae of medium-large polygonal cells with eccentric nuclei and occasional nucleoli. Some irregularly shaped cells had well marked cytoplasmic vacuolation. Mitotic figures were present.

Epithelioid haemangioendothelioma in the parapharyngeal space

2006 ◽  
Vol 120 (6) ◽  
pp. 505-507 ◽  
Author(s):  
J-C Lee ◽  
B-J Lee ◽  
S-G Wang ◽  
H-W Kim
Keyword(s):  
Endothelial Cells ◽  
Facial Nerve ◽  
Head And Neck ◽  
Soft Tissues ◽  
Parapharyngeal Space ◽  
Malignant Potential ◽  
Vascular Neoplasm ◽  
Cytoplasmic Vacuolation ◽  
Upper And Lower Extremities ◽  
Epithelioid Haemangioendothelioma

Epithelioid haemangioendothelioma (EHE) is an uncommon vascular neoplasm which occurs rarely in the head and neck and has an unpredictable clinical behaviour. It is characterized by round or spindle-shaped endothelial cells with cytoplasmic vacuolation. Most often, EHE arises from the soft tissues of the upper and lower extremities, and it has borderline malignant potential. We describe the first reported case of EHE in the parapharyngeal space, which was treated successfully via a transcervical–transparotid approach (following angiography with embolization), without massive intra-operative bleeding or facial nerve damage.

scholarly journals PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation

2018 ◽  
Vol 356 ◽  
pp. 151-158 ◽  
Author(s):  
Ognian C. Ikonomov ◽  
George Altankov ◽  
Diego Sbrissa ◽  
Assia Shisheva
Keyword(s):  
Cytoplasmic Vacuolation

Morphology of Nicotiana tabacum cells grown in contact with lunar material

1973 ◽  
Vol 51 (1) ◽  
pp. 151-156 ◽  
Author(s):  
P. S. Baur ◽  
C. H. Walkinshaw ◽  
R. S. Halliwell ◽  
V. E. Scholes
Keyword(s):  
Nicotiana Tabacum ◽  
Tissue Cultures ◽  
Chloroplast Structure ◽  
Cytoplasmic Vacuolation ◽  
Lunar Material ◽  
Cell Association

Suspension and stationary habituated tobacco tissue cultures were examined histologically and cytologically after treatment with 0.22 g of lunar material. The treated and untreated tissues differed in chloroplast structure and distribution, degree of cell association, cytoplasmic vacuolation and vesiculation, and living to nonliving ratios.

Swelling and cytoplasmic vacuolation

1946 ◽  
Vol 42 (0) ◽  
pp. B253-B254
Author(s):  
E. Fauré-Fremiet
Keyword(s):  
Cytoplasmic Vacuolation

Cytoplasmic vacuolation, intracytoplasmic lumina, and DPAS staining in ductal carcinoma of the breast

2003 ◽  
Vol 28 (6) ◽  
pp. 291-294 ◽  
Author(s):  
Raje Nijhawan ◽  
Arvind Rajwanshi ◽  
Upasana Gautam ◽  
Subhash K. Gupta
Keyword(s):  
Ductal Carcinoma ◽  
Carcinoma Of The Breast ◽  
Cytoplasmic Vacuolation ◽  
Intracytoplasmic Lumina

scholarly journals Cannabinoid Combination Induces Cytoplasmic Vacuolation in MCF-7 Breast Cancer Cells

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4682
Author(s):  
Recardia Schoeman ◽  
Natasha Beukes ◽  
Carminita Frost
Keyword(s):  
Breast Cancer ◽  
Endoplasmic Reticulum ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell Lines ◽  
Effect Analysis ◽  
Cytoplasmic Vacuolation ◽  
Cycle Arrest ◽  
Median Effect Analysis ◽  
Mcf 7

This study evaluated the synergistic anti-cancer potential of cannabinoid combinations across the MDA-MB-231 and MCF-7 human breast cancer cell lines. Cannabinoids were combined and their synergistic interactions were evaluated using median effect analysis. The most promising cannabinoid combination (C6) consisted of tetrahydrocannabinol, cannabigerol (CBG), cannabinol (CBN), and cannabidiol (CBD), and displayed favorable dose reduction indices and limited cytotoxicity against the non-cancerous breast cell line, MCF-10A. C6 exerted its effects in the MCF-7 cell line by inducing cell cycle arrest in the G2 phase, followed by the induction of apoptosis. Morphological observations indicated the induction of cytoplasmic vacuolation, with further investigation suggesting that the vacuole membrane was derived from the endoplasmic reticulum. In addition, lipid accumulation, increased lysosome size, and significant increases in the endoplasmic reticulum chaperone protein glucose-regulated protein 78 (GRP78) expression were also observed. The selectivity and ability of cannabinoids to halt cancer cell proliferation via pathways resembling apoptosis, autophagy, and paraptosis shows promise for cannabinoid use in standardized breast cancer treatment.

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