scholarly journals Bacteriophage P1

2020 ◽  
Author(s):  
Keyword(s):  
Bacteriophage P1

scholarly journals Autoregulation of the Plasmid Addiction Operon of Bacteriophage P1

1996 ◽  
Vol 271 (31) ◽  
pp. 18705-18710 ◽  
Author(s):  
Roy Magnuson ◽  
Hansjörg Lehnherr ◽  
Gauranga Mukhopadhyay ◽  
Michael B. Yarmolinsky
Keyword(s):  
Bacteriophage P1

Bacteriophage P1 tail-fibre and dar operons are expressed from homologous phage-specific late promoter sequences

1989 ◽  
Vol 208 (4) ◽  
pp. 615-622 ◽  
Author(s):  
Angelo Guidolin ◽  
Jean-Marc Zingg ◽  
Hansjörg Lehnherr ◽  
Werner Arber
Keyword(s):  
Late Promoter ◽  
Bacteriophage P1 ◽  
Promoter Sequences

Antibody Expression from the Core Region of the Human IgH Locus Reconstructed in Transgenic Mice Using Bacteriophage P1 Clones

Genomics ◽  
1996 ◽  
Vol 35 (3) ◽  
pp. 405-414 ◽  
Author(s):  
Simon D. Wagner ◽  
Gideon Gross ◽  
Graham P. Cook ◽  
Sarah L. Davies ◽  
Michael S. Neuberger
Keyword(s):  
Transgenic Mice ◽  
Core Region ◽  
Bacteriophage P1 ◽  
Antibody Expression ◽  
The Core ◽  
Igh Locus

scholarly journals RECIPIENT GENE DUPLICATION DURING GENERALIZED TRANSDUCTION

Genetics ◽  
1974 ◽  
Vol 78 (3) ◽  
pp. 809-822
Author(s):  
M Stodolsky
Keyword(s):  
Gene Duplication ◽  
Crossing Over ◽  
Chromosome Fragment ◽  
Bacteriophage P1 ◽  
Recombinant Formation ◽  
Generalized Transduction

ABSTRACT An Hfrl3 ΔProA-lac  deletion recipient, -ΔproA-lac-F-purE+-, has been utilized in a study of the origins of duplications formed during chromosome fragment integration. Among the Pro-Lac+ transductants, some have duplications spanning the F locus. These transductants are, or segregate, strains with F' episomes carrying genes of the duplication. Some of the duplications include purE+, a gene which is not coinherited with lac+ during bacteriophage P1- mediated transduction. Thus recipient genes have been duplicated during recombinant formation. Crossing-over models including replication steps provide a basis for explaining the duplication process.

scholarly journals Genome of Bacteriophage P1

2004 ◽  
Vol 186 (21) ◽  
pp. 7032-7068 ◽  
Author(s):  
Małgorzata B. Łobocka ◽  
Debra J. Rose ◽  
Guy Plunkett ◽  
Marek Rusin ◽  
Arkadiusz Samojedny ◽  
...  
Keyword(s):  
Dna Methyltransferase ◽  
Enteric Bacteria ◽  
Origin Of Replication ◽  
Protein Coding ◽  
Bacteriophage P1 ◽  
E Coli ◽  
Base Content ◽  
Copy Number Plasmid ◽  
Low Copy Number ◽  
Rna Polymerase Holoenzyme

ABSTRACT P1 is a bacteriophage of Escherichia coli and other enteric bacteria. It lysogenizes its hosts as a circular, low-copy-number plasmid. We have determined the complete nucleotide sequences of two strains of a P1 thermoinducible mutant, P1 c1-100. The P1 genome (93,601 bp) contains at least 117 genes, of which almost two-thirds had not been sequenced previously and 49 have no homologs in other organisms. Protein-coding genes occupy 92% of the genome and are organized in 45 operons, of which four are decisive for the choice between lysis and lysogeny. Four others ensure plasmid maintenance. The majority of the remaining 37 operons are involved in lytic development. Seventeen operons are transcribed from σ70 promoters directly controlled by the master phage repressor C1. Late operons are transcribed from promoters recognized by the E. coli RNA polymerase holoenzyme in the presence of the Lpa protein, the product of a C1-controlled P1 gene. Three species of P1-encoded tRNAs provide differential controls of translation, and a P1-encoded DNA methyltransferase with putative bifunctionality influences transcription, replication, and DNA packaging. The genome is particularly rich in Chi recombinogenic sites. The base content and distribution in P1 DNA indicate that replication of P1 from its plasmid origin had more impact on the base compositional asymmetries of the P1 genome than replication from the lytic origin of replication.

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