scholarly journals Bile Duct Biliary Intraepithelial Neoplasia

2020 ◽  
Author(s):  
Keyword(s):  
Bile Duct ◽  
Intraepithelial Neoplasia ◽  
Biliary Intraepithelial Neoplasia

scholarly journals Precursors to Cholangiocarcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Tomas Hucl
Keyword(s):  
Bile Duct ◽  
Natural History ◽  
Biliary Tract ◽  
Intraepithelial Neoplasia ◽  
Mucinous Cystic Neoplasm ◽  
Cystic Neoplasm ◽  
Biliary Tract Cancers ◽  
Biliary Intraepithelial Neoplasia ◽  
Prevention And Early Detection ◽  
Duct Cancer

Cancers of the biliary tract include intra- and extrahepatic cholangiocarcinomas and gallbladder cancer. Biliary tract cancers are diseases with unfavorable prognoses. In recent years, several lesions have been described as precursors that precede biliary cancers. They include flat and microscopic lesions known as biliary intraepithelial neoplasia, macroscopic and tumor-forming intraductal papillary biliary neoplasia, intraductal tubular neoplasia, and mucinous cystic neoplasm of the bile duct. These conditions are rarely diagnosed, while their natural history and progression to cancer have yet to be adequately characterized. This review examines the epidemiology, pathology, molecular biology, diagnosis, and therapy of these various precursors. Further research is required if we are to better understand this evolving field and improve the prevention and early detection of bile duct cancer.

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