scholarly journals Hepatic Triacylglycerol Lipase

2020 ◽  
Author(s):  
Author(s):  
Shuichi Nozaki ◽  
Iichiro Shimomura ◽  
Tohru Funahashi ◽  
Masakazu Menju ◽  
Masaharu Kubo ◽  
...  

1986 ◽  
Vol 236 (1) ◽  
pp. 273-278 ◽  
Author(s):  
S Vilaró ◽  
M Reina ◽  
I Ramírez ◽  
M Llobera

The administration of Intralipid to starved adult rats induces the appearance of lipoprotein lipase (LPL)-like activity in the liver, whereas the so-called hepatic triacylglycerol lipase is unaffected. This LPL-like activity is eluted by 1.5 M-NaCl from heparin-Sepharose columns. This partially purified fraction is inhibited by 1.0 M-NaCl (91%) and by 1.0 mg of protamine sulphate/ml (79%), whereas it is stimulated 69-fold by the presence of 8.0 micrograms of apolipoprotein C-II/ml and inhibited by anti-LPL antibodies. We conclude that Intralipid administration induces the appearance of LPL activity in livers of starved adult rats. Its possible origin is discussed.


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