Bacillary Angiomatosis

A Case of Bacillary Angiomatosis in a Patient with Pancreatic Adenocarcinoma

Journal of Cutaneous Pathology ◽

10.1111/cup.12303 ◽

2014 ◽

Vol 41 (3) ◽

pp. 277-280 ◽

Cited By ~ 3

Author(s):

Collin Blattner ◽

Erick Jacobson-Dunlop ◽

Jason H Miller ◽

Dirk M. Elston

Keyword(s):

Pancreatic Adenocarcinoma ◽

Bacillary Angiomatosis

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Bacillary Angiomatosis: A Unique Cutaneous Complication of Hiv Infection

Canadian Journal of Plastic Surgery ◽

10.1177/229255039500300201 ◽

1995 ◽

Vol 3 (2) ◽

pp. 1-10

Author(s):

Joan Lipa ◽

Walter Peters ◽

Victor Fornasier ◽

Benjamin Fisher

Keyword(s):

Hiv Infection ◽

Definitive Diagnosis ◽

Causal Organism ◽

Bacillary Angiomatosis ◽

Immunodeficiency Virus ◽

Confirmatory Tests ◽

Nodular Lesions ◽

Acquired Immunodeficiency ◽

Immunodeficiency Syndrome ◽

Erythromycin Therapy

As the prevalence of human immunodeficiency virus (HIV) infection increases, so does the recognition of unusual manifestations of this syndrome. This study describes two patients who presented with a unique, rare, cutaneous manifestion of HIV infection. One patient developed an aggressive atypical cellulitis and ascending lymphangitis of the hand, which failed to improve following multiple courses of several different antibiotics. The other patient presented with multiple, vascular, nodular lesions, clinically resembling Kaposi's sarcoma. Routine biopsies and wound cultures were not helpful for diagnosis. A definitive diagnosis of bacillary angiomatosis (BA) was made using a special silver-staining (Warthin-Starry) histological technique and electron microscopy. Both patients responded completely to oral erythromycin therapy. BA is a newly recognized bacterial infection caused by bacteria of the genus Bartonella. It is seen primarily in patients with acquired immunodeficiency syndrome (AIDS), and less commonly in patients with other immunosuppressed conditions. The term BA describes the lesion's pathogenesis (infective-bacillary) and clinico-histology (angiomatosis). The causal organism cannot be cultured reliably and is resistant to most antibiotics. This study reviews these two patients, the differential diagnosis of BA, specific confirmatory tests used in diagnosis, and the treatment outcome of this condition. It is important for the plastic surgeon to understand BA, because it can resemble other common presentations, but it can also be associated with internal involvement leading to mortality. However, when recognized, it can usually be cured by oral erythromycin therapy (500 mg qid) for several weeks.

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Bacillary Angiomatosis

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949510400815 ◽

1995 ◽

Vol 104 (8) ◽

pp. 668-672 ◽

Cited By ~ 9

Author(s):

John G. Batsakis ◽

Jae Y. Ro ◽

Elizabeth E. Frauenhoffer

Keyword(s):

Head And Neck ◽

Acquired Immunodeficiency Syndrome ◽

Opportunistic Infections ◽

Epidemiologic Studies ◽

Cat Scratch Disease ◽

Bacterial Agent ◽

Bacillary Angiomatosis ◽

Mucous Membranes ◽

Acquired Immunodeficiency ◽

Immunodeficiency Syndrome

The acquired immunodeficiency syndrome and other causes of immunosuppression have ushered in a variety of opportunistic infections. One of these is bacillary angiomatosis, a vasoproliferative lesion whose principal causative agent is Rochalimaea henselae. Bacillary angiomatosis, while preponderantly a cutaneous affliction, can be systemic, including involvement of the head and neck mucous membranes. Molecular technology and epidemiologic studies used to identify the bacterial agent of bacillary angiomatosis have also uncovered R henselae as the organism responsible for most cases of cat-scratch disease. Why the same organism promotes two different histopathologic lesions, as seen in bacillary angiomatosis and cat-scratch disease, is unknown.

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Bacillary angiomatosis in an HIV seronegative patient on systemic steroid therapy

British Journal of Dermatology ◽

10.1046/j.1365-2133.1996.d01-1107.x ◽

1996 ◽

Vol 135 (6) ◽

pp. 982-987 ◽

Cited By ~ 21

Author(s):

R.A. SCHWARTZ ◽

M.A. GALLARDO ◽

R. KAPILA ◽

P. GASCON ◽

J. HERSCU ◽

...

Keyword(s):

Steroid Therapy ◽

Systemic Steroid ◽

Bacillary Angiomatosis ◽

Seronegative Patient ◽

Systemic Steroid Therapy

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Cat-scratch Disease and Bacillary Angiomatosis

JAMA ◽

10.1001/jama.1991.03470140050020 ◽

1991 ◽

Vol 266 (14) ◽

pp. 1938 ◽

Cited By ~ 3

Author(s):

Jordan W. Tappero

Keyword(s):

Cat Scratch Disease ◽

Bacillary Angiomatosis

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Cytokines and T-Lymphocute count in patients in the acute and chronic phases of Bartonella bacilliformis infection in an endemic area in peru: a pilot study

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46652011000300006 ◽

2011 ◽

Vol 53 (3) ◽

pp. 149-154 ◽

Cited By ~ 6

Author(s):

Erick Huarcaya ◽

Ivan Best ◽

Juan Rodriguez-Tafur ◽

Ciro Maguiña ◽

Nelson Solórzano ◽

...

Keyword(s):

Pilot Study ◽

Acute Phase ◽

Chronic Phase ◽

Peripheral Tolerance ◽

Bartonella Bacilliformis ◽

Cross Sectional ◽

Bacillary Angiomatosis ◽

Cd8 T Lymphocyte ◽

Ifn Γ ◽

Anti Inflammatory Cytokine

Human Bartonellosis has an acute phase characterized by fever and hemolytic anemia, and a chronic phase with bacillary angiomatosis-like lesions. This cross-sectional pilot study evaluated the immunology patterns using pre- and post-treatment samples in patients with Human Bartonellosis. Patients between five and 60 years of age, from endemic areas in Peru, in the acute or chronic phases were included. In patients in the acute phase of Bartonellosis a state of immune peripheral tolerance should be established for persistence of the infection. Our findings were that elevation of the anti-inflammatory cytokine IL-10 and numeric abnormalities of CD4+ and CD8+ T-Lymphocyte counts correlated significantly with an unfavorable immune state. During the chronic phase, the elevated levels of IFN-γ and IL-4 observed in our series correlated with previous findings of endothelial invasion of B. henselae in animal models.

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