Pulmonary Adenomatosis

Two new cases of congenital cystic adenomatoid malformation of the lung are reported. Both patients died shortly after birth, one at 36 hours and the other on the tenth postnatal day. Cystic adenomatoid malformation is a special form of cystic lung disease characterized by large and small cysts lined variably by a bronchial-type (respiratory) and by cuboidal epithelium. In spite of the bronchial-type epithelium in some of the cysts, bronchial wall elements such as cartilage and mucoserous glands were not demonstrated. There was much elastic tissue in these cysts, of a degree having no counterpart in normal lung. These observations together with the topographic interposition of the cysts with normal appearing alveolar structures suggest a developmental malformation affecting those segments of the lungs normally destined to become the terminal bronchioles, respiratory bronchioles, and alveolar ducts. In one case, groups of alveoli were lined with a tall mucogenic epithelium morphologically resembling that seen in pulmonary adenomatosis of man and jaagsiekte of sheep. The finding is considered the result of alveolar cell metaplasia.

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Sheep Pulmonary Adenomatosis

The Geographical Distribution of Animal Viral Diseases ◽

10.1016/b978-0-12-524180-9.50103-5 ◽

1983 ◽

pp. 385-387

Author(s):

STEWART ODEND'HAL

Keyword(s):

Pulmonary Adenomatosis

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Sheep Pulmonary Adenomatosis: Characterization of Two Pathological Forms Associated with Jaagsiekte Retrovirus

Journal of Comparative Pathology ◽

10.1053/jcpa.1999.0344 ◽

2000 ◽

Vol 122 (1) ◽

pp. 55-65 ◽

Cited By ~ 34

Author(s):

M García-Goti ◽

L González ◽

C Cousens ◽

N Cortabarría ◽

AB Extramiana ◽

...

Keyword(s):

Pulmonary Adenomatosis

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Detection of Jaagsiekte sheep retrovirus in the peripheral blood during the pre-clinical period of ovine pulmonary adenomatosis

Genetics and Molecular Research ◽

10.4238/gmr.15038521 ◽

2016 ◽

Vol 15 (3) ◽

Cited By ~ 2

Author(s):

Y. Liu ◽

Y.F. Zhang ◽

X.L. Sun ◽

S.Y. Liu

Keyword(s):

Peripheral Blood ◽

Jaagsiekte Sheep Retrovirus ◽

Pulmonary Adenomatosis

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Outbreak of sheep pulmonary adenomatosis in the Irish Republic

Veterinary Record ◽

10.1136/vr.124.7.177-d ◽

1989 ◽

Vol 124 (7) ◽

pp. 177-177

Author(s):

B. Parker ◽

A. Wrathall ◽

R. Saunders ◽

M. Dawson ◽

S. Done ◽

...

Keyword(s):

Irish Republic ◽

Pulmonary Adenomatosis

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Prevalence of Pneumonia in Sheep and Goats Slaughtered at Elfora Bishoftu Export Abattoir, Ethiopia: A Pathological Investigation

Journal of Veterinary Medicine ◽

10.1155/2019/5169040 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 2

Author(s):

Berhanu Mekibib ◽

Tadesse Mikir ◽

Amene Fekadu ◽

Rahmeto Abebe

Keyword(s):

Histopathological Examination ◽

Small Ruminants ◽

Cost Effective ◽

Epidemiological Data ◽

Prevention Measures ◽

Sheep And Goats ◽

Effective Interventions ◽

Ancillary Test ◽

Pulmonary Adenomatosis ◽

Ovine Progressive Pneumonia

Accurate clinical diagnosis of pneumonia, the leading cause of mortality in small ruminants, is difficult and usually requires postmortem examination of the lungs. An active abattoir survey was conducted between November 2017 and April 2018 to estimate the prevalence and characterize the gross and histopathological lesions of pneumonic lungs in 864 clinically healthy young small ruminants (490 sheep and 374 goats aged 1.5 to 3 years) raised for meat in different parts of the country and slaughtered at Elfora Bishoftu export abattoir, Ethiopia. Out of the total lungs examined grossly, pneumonic lesions were found in 158 (18.29%) lungs. On histopathological examination of the lungs with gross pneumonic lesion, however, typical pneumonic lesions were diagnosed in 148 (17.13%) lungs only. No significant (p>0.05) difference was noted in the prevalence of pneumonia between sheep (17.14%) and goats (17.11%) in histopathological examination. Based on the predominant histopathological findings, the pneumonic lesions were characterized as interstitial pneumonia (41.9%), acute suppurative bronchopneumonia (25.7%), acute fibrinous bronchopneumonia (24.3%), chronic bronchopneumonia (6.1%), aspiration pneumonia (4.7%), bronchointerstitial pneumonia (3.4%), and ovine pulmonary adenomatosis (3.4%). The study further showed the spread of ovine pulmonary adenomatosis and ovine progressive pneumonia (Maedi) from the central highlands to areas that were previously free from these diseases. Due to its better diagnostic capacity, histopathology should be employed routinely as an ancillary test in the major abattoirs and regional veterinary laboratories to generate additional epidemiological data for a better disease control and prevention measures. Further studies are also recommended to identify the etiological agents of pneumonia in sheep and goats and thereby to formulate feasible and cost-effective interventions.

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