scholarly journals Erythromycin Stearate

2020 ◽  
Author(s):  
Keyword(s):  
Erythromycin Stearate

scholarly journals Quality assessment of brands of erythromycin stearate tablets marketed in Abuja, Nigeria

2020 ◽  
Vol 17 (1) ◽  
pp. 29-33
Author(s):  
Kudirat B. Mustapha ◽  
Marlene D. Ekpo ◽  
Isa H. Galadima ◽  
Rukaiyatu A. Kirim ◽  
Olubukola A. Odeniran ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Quality Evaluation ◽  
Hardness Test ◽  
Spectrophotometric Analysis ◽  
Assessment Study ◽  
Uniformity Test ◽  
Quality Assessment Study ◽  
Percentage Weight ◽  
Pharmaceutical Industries ◽  
Erythromycin Stearate

Erythromycin is one of the most frequently prescribed antibiotics. With the increasing number of pharmaceutical industries, the possibility of  purchasing a substandard product is on the high side. This makes it necessary to subject various commercially produced brands of erythromycin to quality evaluation in order to ascertain the quality. In this quality assessment study, six (6) brands of erythromycin tablets were subjected to physicochemical assay using standard physical methods and UV/VIS spectrophotometric analysis at 480 nm. The calibration curve for reference erythromycin was linear over a concentration range of 10-100 μg/ml with a correlation coefficient (R2) of 0.999. All the brands had standard deviation of weight greater than ±5 for the weight uniformity test. 66.67% of the brands passed the test for content of active ingredient. 83.33% of the brands examined passed the hardness test. All the brands failed the friability test because the percentage weight loss are greater than 1% as specified in the official book. Keywords: Erythromycin stearate; Tablets; Brands; Pharmaceutical Industries

In vitro Binding Chemistry of Erythromycin Stearate and Omeprazole to Bovine Serum Albumin

Pharmacologia ◽  
2014 ◽  
Vol 5 (3) ◽  
pp. 91-97 ◽  
Author(s):  
Fatema Kanak ◽  
Md. Shariful Islam ◽  
Mohammad Shahriar ◽  
Md. Imran-ul-H ◽  
Mohammad Fahim Kadir
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
In Vitro Binding ◽  
Vitro Binding ◽  
Erythromycin Stearate

Erythromycin Stearate against Systemic Amebiasis in Colombia 1

1955 ◽  
Vol 4 (4) ◽  
pp. 693-698 ◽  
Author(s):  
Hamilton H. Anderson ◽  
Thomas L. Nelson ◽  
Carlos Carbono ◽  
José Diaz
Keyword(s):  
Erythromycin Stearate

Neural control of small intestinal giant migrating contractions

1994 ◽  
Vol 266 (4) ◽  
pp. G576-G584 ◽  
Author(s):  
M. F. Otterson ◽  
S. K. Sarna
Keyword(s):  
Small Intestine ◽  
Neural Control ◽  
Loop Formation ◽  
Descending Inhibition ◽  
Enteric Nerves ◽  
Small Intestinal ◽  
Erythromycin Lactobionate ◽  
Erythromycin Stearate ◽  
Spontaneous Phase ◽  
Giant Migrating Contractions

We investigated the neural mechanisms of control of giant migrating contractions (GMCs) in five conscious dogs. After control recordings, a Thiry-Vella loop was prepared from the middle segment, and the remaining two segments were reanastomosed. GMCs were stimulated by intravenous administration of fentanyl and erythromycin lactobionate, oral administration of loperamide and erythromycin stearate, and gastric or intraluminal administration of cider vinegar in the loop. In the intact state, the agents stimulated GMCs in all three segments, and they propagated uninterruptedly from the point of their origin to the terminal ileum. The propagation velocity of GMCs increased, whereas that of migrating motor complexes (MMCs) decreased distally. After Thiry-Vella loop formation, the agents stimulated GMCs independently in the three segments, and they propagated only to the end of the segment in which they started. In the intact small intestine, the GMCs produced ascending and descending inhibition of spontaneous phase II contractions but did not interrupt the caudad propagation of the ongoing MMC. After Thiry-Vella loop formation, the ascending inhibition was unaltered, but the descending inhibition occurred only in the segment containing the GMC. We conclude that the propagation of GMCs in the small intestine is controlled by the enteric nerves. The extrinsic nerves control the ascending inhibition produced by GMCs, whereas the enteric nerves control the descending inhibition.

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