scholarly journals Atypical Lymphocyte Count

2020 ◽  
Author(s):  
Keyword(s):  
Lymphocyte Count ◽  
Atypical Lymphocyte

scholarly journals PS1289 THE ATYPICAL LYMPHOCYTE COUNT: A NOVEL PREDICTIVE FACTOR FOR SEVERE DENGUE INFECTION

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 589-590
Author(s):  
V. Abeysuriya ◽  
C. Choong ◽  
S. de Mel ◽  
B.U. Thilakawardana ◽  
P. de Mel ◽  
...  
Keyword(s):  
Predictive Factor ◽  
Lymphocyte Count ◽  
Dengue Infection ◽  
Severe Dengue ◽  
Atypical Lymphocyte

scholarly journals Atypical lymphocyte count correlates with the severity of dengue infection

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0215061 ◽  
Author(s):  
Choong Shi Hui Clarice ◽  
Visula Abeysuriya ◽  
Sanjay de Mel ◽  
Basuru Uvindu Thilakawardana ◽  
Primesh de Mel ◽  
...  
Keyword(s):  
Lymphocyte Count ◽  
Dengue Infection ◽  
Atypical Lymphocyte

The atypical lymphocyte count: a novel predictive factor for severe thrombocytopenia related to dengue

2020 ◽  
Vol 114 (6) ◽  
pp. 424-432
Author(s):  
Visula Abeysuriya ◽  
Clarice Shi Hui Choong ◽  
Basuru Uvindu Thilakawardana ◽  
Primesh de Mel ◽  
Malka Shalindi ◽  
...  
Keyword(s):  
Platelet Count ◽  
Predictive Factor ◽  
Lymphocyte Count ◽  
Characteristic Curve ◽  
Dengue Infection ◽  
Severe Dengue ◽  
Full Blood Count ◽  
Severe Thrombocytopenia ◽  
Atypical Lymphocyte ◽  
Predictive Values

Abstract Background Early identification of patients at risk of severe dengue disease (DD) is critical to guide its management. We evaluated whether the atypical lymphocyte count (ALC), generated from the Sysmex automated full blood count analyzer, is predictive of severe thrombocytopenia secondary to Dengue infection. Methods We prospectively collected data on patients admitted with DD between December 2017 and October 2018. ALC data were extracted from the Sysmex XS500i analyzer from day 1 to day 7 of admission. Clinical data were obtained from patients' medical records. Results We enrolled 256 patients with DD. A negative correlation between ALC on admission and platelet count on day 5 to day 7 (Spearmen's correlation; day 5:-0.485, day 6:-0.428 and day 7:-0.344) (p=0.001) was observed. Based on receiver operator characteristic curve analysis, we found that an ALC of >0.5x103/L had 90% sensitivity and 70% specificity for severe thrombocytopenia (platelet count <50x109/L) on day 5. The positive and negative predictive values were 74.4 and 91.2%, respectively (power 84.7). Conclusions We propose that ALC on admission may be a novel negative predictive factor for severe thrombocytopenia on day 5 to day 7 of DD. Further studies are required to validate our findings and evaluate whether ALC is predictive of other complications of DD.

A Quantitative Ultrastructural Study of Peripheral Blood Lymphocytes Containing Parallel Tubular Arrays in Epstein-Barr Virus and Cytomegalo-Virus Mononucleosis

1981 ◽  
Vol 39 ◽  
pp. 454-455
Author(s):  
C. M. Payne ◽  
P. M. Tennican
Keyword(s):  
Peripheral Blood ◽  
Lymphocyte Count ◽  
Epstein Barr Virus ◽  
Absolute Lymphocyte Count ◽  
Peripheral Blood Lymphocytes ◽  
Clinical State ◽  
Barr Virus ◽  
The Absolute ◽  
Epstein Barr ◽  
Tubular Arrays

In the normal peripheral circulation there exists a sub-population of lymphocytes which is ultrastructurally distinct. This lymphocyte is identified under the electron microscope by the presence of cytoplasmic microtubular-like inclusions called parallel tubular arrays (PTA) (Figure 1), and contains Fc-receptors for cytophilic antibody. In this study, lymphocytes containing PTA (PTA-lymphocytes) were quantitated from serial peripheral blood specimens obtained from two patients with Epstein -Barr Virus mononucleosis and two patients with cytomegalovirus mononucleosis. This data was then correlated with the clinical state of the patient.It was determined that both the percentage and absolute number of PTA- lymphocytes was highest during the acute phase of the illness. In follow-up specimens, three of the four patients' absolute lymphocyte count fell to within normal limits before the absolute PTA-lymphocyte count.In one patient who was followed for almost a year, the absolute PTA- lymphocyte count was consistently elevated (Figure 2). The estimation of absolute PTA-lymphocyte counts was determined to be valid after a morphometric analysis of the cellular areas occupied by PTA during the acute and convalescent phases of the disease revealed no statistical differences.

scholarly journals Prediction of survival using absolute lymphocyte count for newly diagnosed patients with multiple myeloma: a retrospective study

2008 ◽  
Vol 141 (6) ◽  
pp. 792-798 ◽  
Author(s):  
Hilmi Ege ◽  
Morie A. Gertz ◽  
Svetomir N. Markovic ◽  
Martha Q. Lacy ◽  
Angela Dispenzieri ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Retrospective Study ◽  
Lymphocyte Count ◽  
Absolute Lymphocyte Count ◽  
Newly Diagnosed ◽  
Prediction Of Survival
Sign in / Sign up

Export Citation Format

Share Document