scholarly journals Kluyvera cryocrescens

2020 ◽  
Author(s):  
Antibiotics ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 149 ◽  
Author(s):  
Ying Li ◽  
Li Luo ◽  
Zhijiao Xiao ◽  
Guangxi Wang ◽  
Chengwen Li ◽  
...  

Carbapenem-resistant Enterobacteriaceae have been a global public health issue in recent years. Here, a carbapenem-resistant Kluyvera cryocrescens strain SCW13 was isolated from hospital sewage, and was then subjected to whole-genome sequencing (WGS). Based on WGS data, antimicrobial resistance genes were identified. Resistance plasmids were completely circularized and further bioinformatics analyses of plasmids were performed. A conjugation assay was performed to identify a self-transmissible plasmid mediating carbapenem resistance. A phylogenetic tree was constructed based on the core genome of publicly available Kluyvera strains. The isolate SCW13 exhibited resistance to cephalosporin and carbapenem. blaNDM-1 was found to be located on a ~53-kb self-transmissible IncX3 plasmid, which exhibited high similarity to the previously reported pNDM-HN380, which is an epidemic blaNDM-1-carrying IncX3 plasmid. Further, we found that SCW13 contained a chromosomal blaKLUC-2 gene, which was the probable origin of the plasmid-born blaKLUC-2 found in Enterobacter cloacae. Phylogenetic analysis showed that K. cryocrescens SCW13 exhibited a close relationship with K. cryocrescens NCTC10483. These findings highlight the further dissemination of blaNDM through clonal IncX3 plasmids related to pNDM-HN380 among uncommon Enterobacteriaceae strains, including Kluyvera in this case.


2001 ◽  
Vol 18 (1) ◽  
Author(s):  
MONICA GIL D DE M ◽  
MARITZA NAVARRETE C ◽  
VICTOR LIZAMA A ◽  
ANGELA ZAROR C ◽  
EMILIA ARCE G

2018 ◽  
Vol 73 (11) ◽  
pp. 3206-3208 ◽  
Author(s):  
Paolo Gaibani ◽  
Simone Ambretti ◽  
Erika Scaltriti ◽  
Miriam Cordovana ◽  
Andrea Berlingeri ◽  
...  

2001 ◽  
Vol 175 (6) ◽  
pp. 395-404 ◽  
Author(s):  
Esteban Martínez-García ◽  
Antonio Tormo ◽  
Juana Navarro-Llorens

2020 ◽  
Vol 42 (11) ◽  
pp. 2367-2377
Author(s):  
Xue-Mei Kang ◽  
Xue Cai ◽  
Zhi-Qiang Liu ◽  
Yu-Guo Zheng

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