scholarly journals Inbred Strain

2020 ◽  
Author(s):  
Keyword(s):  
Inbred Strain

scholarly journals Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.

Genetics ◽  
1989 ◽  
Vol 122 (3) ◽  
pp. 669-679
Author(s):  
L D Siracusa ◽  
A M Buchberg ◽  
N G Copeland ◽  
N A Jenkins
Keyword(s):  
Molecular Markers ◽  
Inbred Strain ◽  
Mouse Chromosome ◽  
Recombinant Inbred ◽  
Recombinant Inbred Strain ◽  
Interspecific Backcross ◽  
Chromosome 2 ◽  
Chromosome 4 ◽  
Agouti Locus ◽  
Mouse Chromosome 2

Abstract Recombinant inbred strain and interspecific backcross mice were used to create a molecular genetic linkage map of the distal portion of mouse chromosome 2. The orientation and distance of the Ada, Emv-13, Emv-15, Hck-1, Il-1a, Pck-1, Psp, Src-1 and Svp-1 loci from the beta 2-microglobulin locus and the agouti locus were established. Our mapping results have provided the identification of molecular markers both proximal and distal to the agouti locus. The recombinants obtained provide valuable resources for determining the direction of chromosome walking experiments designed to clone sequences at the agouti locus. Comparisons between the mouse and human genome maps suggest that the human homolog of the agouti locus resides on human chromosome 20q. Three loci not present on mouse chromosome 2 were also identified and were provisionally named Psp-2, Hck-2 and Hck-3. The Psp-2 locus maps to mouse chromosome 14. The Hck-2 locus maps near the centromere of mouse chromosome 4 and may identify the Lyn locus. The Hck-3 locus maps near the distal end of mouse chromosome 4 and may identify the Lck locus.

scholarly journals Curly-whiskers and its linkage with tail-kinks in linkage group II of the mouse

1966 ◽  
Vol 8 (1) ◽  
pp. 111-113 ◽  
Author(s):  
D. S. Falconer ◽  
J. H. Isaacson
Keyword(s):  
Linkage Group ◽  
Inbred Strain ◽  
Recessive Gene ◽  
Coat Colour ◽  
Group Ii ◽  
Research Institute

Curly-whiskers (cw) is a recessive gene which was found in 1958 by Mr C. J. W. Smith of the Chester Beatty Research Institute, London. It arose in a subline of the CBA/Cbi inbred strain. The first mutant animals were one male and one female in a litter of five. The two mutants were mated together and a sib-mated subline was continued from them in which 500 mice were bred, all of which were curly-whiskered. This established the mutant to be fully penetrant. Curly-whiskers resembles the hair-waving genes in causing waving of the vibrissae, but it has no obvious waving effect on the hairs of the coat. The coat texture is, however, slightly abnormal and Mr Smith noted also that on the CBA background there was an appreciable darkening of the coat colour. Homozygotes (cw/cw) are easily classifiable soon after birth by the curled vibrissae. Heterozygotes (+/cw) often have slightly curled vibrissae, and the gene is therefore not fully recessive; but the distinction between +/cw and +/+ could not be relied on, and in the linkage tests cw was treated as a recessive gene.

scholarly journals Quantitative Trait Loci Determining Weight Reduction of Testes and Pituitary by Diethylstilbesterol in LEXF and FXLE Recombinant Inbred Strain Rats

2006 ◽  
Vol 55 (2) ◽  
pp. 91-95 ◽  
Author(s):  
Masayoshi TACHIBANA ◽  
Lingmin LU ◽  
Hiroshi HIAI ◽  
Atsushi TAMURA ◽  
Yoshibumi MATSUSHIMA ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Inbred Strain ◽  
Weight Reduction ◽  
Quantitative Trait ◽  
Recombinant Inbred ◽  
Recombinant Inbred Strain ◽  
Trait Loci

Behavioral Characterization of Wild Derived Male Mice (Mus musculus musculus) of the PWD/Ph Inbred Strain: High Exploration Compared to C57BL/6J

2004 ◽  
Vol 34 (6) ◽  
pp. 621-630 ◽  
Author(s):  
Cathy Fernandes ◽  
Lin Liu ◽  
Jos� L. Paya-Cano ◽  
So?a Gregorov� ◽  
Ji?� Forejt ◽  
...  
Keyword(s):  
Inbred Strain ◽  
Mus Musculus ◽  
Male Mice ◽  
Mus Musculus Musculus ◽  
Behavioral Characterization

A spontaneous ankle deformity in an inbred strain of mouse

1978 ◽  
Vol 124 (4) ◽  
pp. 189-194 ◽  
Author(s):  
Mark Walton
Keyword(s):  
Inbred Strain

Inherited congenital kidney absence in an inbred strain of rats

1953 ◽  
Vol 115 (4) ◽  
pp. 635-639 ◽  
Author(s):  
Walter C. Morgan
Keyword(s):  
Inbred Strain

The Action of Diethylstilboestrol on the Prostatic Epithelium of the Mouse

1947 ◽  
Vol s3-88 (1) ◽  
pp. 45-53
Author(s):  
E. S. HORNING
Keyword(s):  
Golgi Apparatus ◽  
Inbred Strain ◽  
Normal Condition ◽  
Morphological Changes ◽  
Anterior Lobe ◽  
Cellular Changes ◽  
Prostatic Epithelium

1. The cellular changes in the prostatic epithelium of an inbred strain of mice (R III), following short periods of treatment with large doses of oestrogen, are described. 2. The Golgi apparatus in the cells of the prostatic epithelium affords a precise indication of the degree of stimulation induced by oestrogenic substances. 3. Specific morphological changes in the Golgi substance occur in the epithelium of the anterior lobe of the prostate after 8 days' treatment. Similar changes, following longer periods of treatment, also occur in the dorsal and ventral lobes. 4. Withdrawal of oestrogenic stimulation after 20 days' treatment with relatively large doses is followed by a return of the prostatic epithelium and the Golgi apparatus to their normal condition in 21 days.

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