scholarly journals Amino Acid/Electrolyte Mixture-based Dietary Supplement

2020 ◽  
Author(s):  
2018 ◽  
Vol 10 (9) ◽  
pp. 45 ◽  
Author(s):  
K Naidoo ◽  
R Naidoo ◽  
V Bangalee

BACKGROUND: The South African dietary supplement market will undergo a period of transition within the next few years due to the establishment of the South African Health Products Regulatory Authority (SAHPRA), which has superseded the former Medicines Control Council (MCC). While regulatory steps are yet to be fully outlined, products such as whey protein, regarded as food, will be governed by the Department of Health R429 draft Regulations Relating to the Labelling and Advertising of Foods. The guideline provides for the minimum value of essential amino acids (plus cysteine and tyrosine) per gram of protein that products claiming to contain protein will be required to comply with. Determining the compliance levels of whey protein products currently available will assist in establishing the readiness of the dietary supplement industry for regulation, and provide an indication of the overall state of the industry.OBJECTIVES: To determine the amino acid profile of whey protein powder and compare analysed content to manufacturer stated content.To compare analysed amino acid content to the Department of Health R429 draft Regulations Relating to the Labelling and Advertising of Food template amino acid profile.METHOD: 15 of the best-selling whey protein products available in South Africa were selected for amino acid analysis. Tested amino acid content were compared to the label stated claim and the amino acid reference pattern, as stated in the Department of Health R429 draft Regulations Relating to the Labelling and Advertising of Foods.RESULTS: Sixty percent (60%) of products tested were non-compliant with the Department of Health R429 draft Regulations Relating to the Labelling and Advertising of Foods. Of the 15 products tested, 11 were manufactured in South Africa, with 8 being non-compliant to the guideline amino acid profile. Considerable variance was noted in the manufacturer stated and the tested amino acid content (ranging from 16–48% variance).CONCLUSION: Many of the whey protein products available in South Africa are not compliant to proposed industry guidelines. The considerable variance noted highlights the need for greater oversight of the industry with clearly defined regulatory procedures.


1981 ◽  
pp. 153-158 ◽  
Author(s):  
H. Lösgen ◽  
E. Neumann ◽  
G. Eisenbach ◽  
F. W. Schmidt ◽  
G. Brunner

2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Chih-Yin Tai ◽  
Jordan M Joy ◽  
Paul H Falcone ◽  
Laura R Carson ◽  
Matt M Mosman ◽  
...  

1973 ◽  
Vol 26 (3) ◽  
pp. 635 ◽  
Author(s):  
PJ Reis ◽  
DA Tunks ◽  
LF Sharry

Plasma amino acid patterns were studied in sheep receiving varying amounts of DL- or L-methionine (0'6-10�0 g/day) or L-cystine (2�0 and 8�0 g/day) as abomasal supplements or DL-methionine (10 g/day) as a dietary supplement.


2008 ◽  
Vol 86 (12) ◽  
pp. 1126-1137 ◽  
Author(s):  
Rahmat Sadeghi

The extended NRTL and Wilson local composition models for amino acid solutions have been modified for the representation of the phase equilibrium behavior of aqueous amino acid – electrolyte solutions by considering cells with random composition for the reference Gibbs energies or enthalpies of local composition cells with a central amino acid molecule and also with a central ion. These new local composition models, which have a molecular thermodynamic framework, have been used to model the vapor–liquid and solid–liquid equilibrium behavior of amino acids and small peptides in aqueous solutions as functions of temperature, ionic strength, and amino acid compositions. The utility of the models is demonstrated with a successful representation of the activity coefficients and the solubility of several amino acids in different aqueous solutions.Key words: amino acid, NRTL, Wilson, activity coefficient, solubility, aqueous solution.


1996 ◽  
Vol 6 (3) ◽  
pp. 295-306 ◽  
Author(s):  
André X. Bigard ◽  
Pierre Lavier ◽  
Lionel Ullmann ◽  
Hélène Legrand ◽  
Philippe Douce ◽  
...  

This study was conducted to test the hypothesis that a branched-chain amino acid (BCAA) supplementation would minimize changes in body composition and alterations in plasma amino acid profile induced by prolonged exercises at altitude. Twenty-four highly trained subjects participated in six successive sessions of ski mountaineering (6-8 hr duration, altitude 2,500-4,100 m). Twelve subjects took a dietary supplement of BCAA (BCAA group) and 12 took a dietary supplement that was 98% carbohydrate (C group). Body weight decreased in C subjects (-2.1%,p < .01), while the body weight loss recorded in the BCAA group was not statistically significant (-1.2%, NS). Changes in body composition that resulted from repeated skiing exercise at altitude were not significantly minimized by BCAA administration. Peak power output recorded during an incremental bicycle exercise decreased in C subjects but did not change significantly in BCAA subjects. Results of this study demonstrate that neither changes in body composition related to the ski mountaineering program nor muscular performance during isometric contraction was significantly affected by BCAA administration.


2020 ◽  
Author(s):  
Yasuteru Sakurai ◽  
Mya Myat Ngwe Tun ◽  
Yohei Kurosaki ◽  
Takaya Sakura ◽  
Daniel Ken Inaoka ◽  
...  

AbstractThe current COVID-19 pandemic requires urgent development of effective therapeutics. 5-amino levulinic acid (5-ALA) is a naturally synthesized amino acid and has been used for multiple purposes including as an anticancer therapy and as a dietary supplement due to its high bioavailability. In this study, we demonstrated that 5-ALA treatment potently inhibited infection of SARS-CoV-2, a causative agent of COVID-19. The antiviral effects could be detected in both human and non-human cells, without significant cytotoxicity. Therefore, 5-ALA is a candidate as an oral antiviral drug for COVID-19.


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