scholarly journals Proenkephalin-A

2020 ◽  
Author(s):  
Keyword(s):  
Proenkephalin A

Expression of the proenkephalin A gene in organotypic cultures of neocortex from newborn rats

1996 ◽  
Vol 35 (1-2) ◽  
pp. 157-163 ◽  
Author(s):  
Lothar Just ◽  
Claudia Olenik ◽  
Bernd Heimrich ◽  
Dieter K. Meyer
Keyword(s):  
Newborn Rats ◽  
Organotypic Cultures ◽  
Proenkephalin A

Synthesis of a specific oligodeoxyribonucleotide probe and its use for studying proenkephalin A gene expression

1987 ◽  
Vol 76 (1) ◽  
pp. 74-80 ◽  
Author(s):  
David C.-C. Wan ◽  
Denis Scanlon ◽  
Barbara Power ◽  
Chung-lit Choi ◽  
Peter Hudson ◽  
...  
Keyword(s):  
Gene Expression ◽  
Proenkephalin A

Met-enkephalin is preferentially transported into the peripheral processes of primary afferent fibres in both control and HSV1-driven proenkephalin A overexpressing rats

Neuroscience ◽  
2001 ◽  
Vol 103 (4) ◽  
pp. 1073-1083 ◽  
Author(s):  
J.-M Antunes bras ◽  
C Becker ◽  
S Bourgoin ◽  
M.-C Lombard ◽  
F Cesselin ◽  
...  
Keyword(s):  
Primary Afferent ◽  
Proenkephalin A

The proenkephalin-A-derivative Met-enkephalin-Arg-Gly-Leu is not present in the feline species

Neuropeptides ◽  
1990 ◽  
Vol 17 (4) ◽  
pp. 171-176 ◽  
Author(s):  
A. Cupo ◽  
L. Leger ◽  
Y. Charnay ◽  
O. Fourrier ◽  
T. Jarry ◽  
...  
Keyword(s):  
Proenkephalin A

scholarly journals Proenkephalin: A New Biomarker for Glomerular Filtration Rate and Acute Kidney Injury

Nephron ◽  
2020 ◽  
Vol 144 (12) ◽  
pp. 655-661
Author(s):  
Mina Khorashadi ◽  
Remi Beunders ◽  
Peter Pickkers ◽  
Matthieu Legrand
Keyword(s):  
Acute Kidney Injury ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Kidney Function ◽  
Filtration Rate ◽  
Kidney Injury ◽  
Peptide Family ◽  
Estimate Glomerular Filtration Rate ◽  
Reduced Kidney Function ◽  
Proenkephalin A

Assessment of kidney function is primarily based on urine output and Creatinine (Cr)-based methods to estimate glomerular filtration rate (GFR). The latter is confounded as Cr is not exclusively filtered by the kidney and rises relatively late after the onset of acute kidney injury (AKI). This leads to delays in recognition of reduced kidney function and diagnosis of AKI, particularly in critically ill patients where kidney function can change rapidly. The gold standard methods of GFR determination, such as inulin or iohexol clearance, are labor intensive and unfeasible in acute clinical settings. Proenkephalin A 119–159 (PENK) has been intensively studied as a novel biomarker of kidney function. PENK belongs to the enkephalin peptide family and is freely filtrated in the glomerulus. Plasma PENK concentration appears to correlate strongly with GFR. Moreover, increased plasma PENK concentrations are found to be associated with long-term kidney outcomes and mortality. In this review, we summarize the role of PENK in assessment of kidney function and its capacity to predict various clinical outcomes.

Midregional Proenkephalin A and N-terminal Protachykinin A are decreased in the cerebrospinal fluid of patients with dementia disorders and acute neuroinflammation

2010 ◽  
Vol 221 (1-2) ◽  
pp. 62-67 ◽  
Author(s):  
Andrea Ernst ◽  
Katharina Buerger ◽  
Oliver Hartmann ◽  
Richard Dodel ◽  
Carmen Noelker ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Proenkephalin A
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