Witch Hazel-containing Anti-Hemorroidal Formulation

2020 ◽  
Author(s):  
Keyword(s):  
Witch Hazel

American witch hazel—History, nomenclature and modern utilization

1953 ◽  
Vol 7 (4) ◽  
pp. 359-381 ◽  
Author(s):  
Edmund H. Fulling
Keyword(s):  
Witch Hazel

scholarly journals Witch Hazel Significantly Improves the Efficacy of Commercially Available Teat Dips

Pathogens ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 92 ◽  
Author(s):  
Reuven Rasooly ◽  
Adel Molnar ◽  
Paula Do ◽  
Gianluca Morroni ◽  
Lucia Brescini ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Economic Loss ◽  
Toxin Production ◽  
Gram Negative Bacteria ◽  
Bacterial Survival ◽  
High Concentration ◽  
Witch Hazel ◽  
Intramammary Infections ◽  
Gram Positive Bacteria ◽  
Associated Conditions

Bovine intramammary infections (IMIs) are the main cause of economic loss in milk production. Antibiotics are often ineffective in treating infections due to antimicrobial resistance and the formation of bacterial biofilms that enhance bacterial survival and persistence. Teat dips containing germicides are recommended to prevent new IMIs and improve udder health and milk quality. IMIs are often caused by staphylococci, which are Gram-positive bacteria that become pathogenic by forming biofilms and producing toxins. As a model for a teat dip (DIP), the BacStop iodine-based teat dip (DIP) was used. Witch hazel extract (whISOBAX (WH)) was tested because it contains a high concentration of the anti-biofilm/anti-toxin phenolic compound hamamelitannin. We found that the minimal inhibitory or bactericidal concentrations of DIP against planktonic S. epidermidis cells increased up to 160-fold in the presence of WH, and that DIP was 10-fold less effective against biofilm cells. While both DIP and WH are effective in inhibiting the growth of S. aureus, only WH inhibits toxin production (tested for enterotoxin-A). Importantly, WH also significantly enhances the antibacterial effect of DIP against Gram-negative bacteria that can cause IMIs, like Escherichia coli and Pseudomonas aeruginosa. Put together, these results suggest that the antibacterial activity of DIP combined with WH is significantly higher, and thus have potential in eradicating bacterial infections, both in acute (planktonic-associated) and in chronic (biofilm-associated) conditions.

Witch Hazel (Hamamelis virginiana) Fractions and the Importance of Gallate MoietiesElectron Transfer Capacities in Their Antitumoral Properties

2008 ◽  
Vol 56 (24) ◽  
pp. 11675-11682 ◽  
Author(s):  
Daneida Lizárraga ◽  
Sonia Touriño ◽  
Fernando J. Reyes-Zurita ◽  
Theo M. de Kok ◽  
Joost H. van Delft ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Witch Hazel ◽  
Electron Transfer Capacities

scholarly journals The Protective Effect of Hamamelis virginiana Stem and Leaf Extract on Fine Dust-Induced Damage on Human Keratinocytes

Cosmetics ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 119
Author(s):  
Jiyoung Choi ◽  
Dongki Yang ◽  
Mi Yeon Moon ◽  
Gi Yeon Han ◽  
Moon Sik Chang ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Tight Junction ◽  
Leaf Extract ◽  
Inflammatory Marker ◽  
Human Keratinocytes ◽  
Skin Care ◽  
Witch Hazel ◽  
Junction Protein ◽  
Skin Care Products

Witch hazel extracts have been used for decades as cosmetic ingredients in skin care products. Our present study aims to evaluate its potential in anti-pollution products using a previously reported in vitro model. Calcium is a universal second messenger, and we used human respiratory and skin cells to detect changes in intracellular Ca2+ concentrations upon particulate matter contact. Both an increase in pro-inflammatory markers and a decrease in tight junction proteins were confirmed, as previously reported. Witch hazel stem and leaf extract showed significant attenuation of Ca2+ response upon the challenge; it displayed systematic regulations of the signal generator, PAR-2; a pro-inflammatory marker, NF-κB; and a tight junction protein, Occludin. We identified hexagalloylglucose from the extract and concluded that it is a major component regulating protection from particulate matter. Based on these results, witch hazel extract containing hexagalloylglucose is an active ingredient in anti-pollution skin care products.

scholarly journals Distilled Extract of Witch Hazel

1895 ◽  
Vol 40 (1037supp) ◽  
pp. 16579-16579
Author(s):  
W. D. Hoeffken
Keyword(s):  
Witch Hazel
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