Gonadotropin Secretion Abnormality

2020 ◽  
Author(s):  
Keyword(s):  
Gonadotropin Secretion

Cocaine impairs follicular phase pulsatile gonadotropin secretion in rhesus monkeys

1998 ◽  
Vol 5 (1) ◽  
pp. 93A-93A
Author(s):  
E CHEN ◽  
M LUTHER ◽  
A MORENO ◽  
T KING ◽  
R SCHENKEN
Keyword(s):  
Rhesus Monkeys ◽  
Follicular Phase ◽  
Gonadotropin Secretion

RU 486: actions on gonadotropin secretion and antagonism of progesterone effects in gonadotrophs

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S187-S188 ◽  
Author(s):  
O. ORTMANN ◽  
G. EMONS ◽  
R. KNUPPEN ◽  
K.J. CATT
Keyword(s):  
Gonadotropin Secretion ◽  
Ru 486

N-methyl-D,L-aspartate (NMDA) stimulates gonadotropin secretion in the ovine fetus through gonadotropin-releasing hormone (GnRH) release

1988 ◽  
Vol 117 (4_Suppl) ◽  
pp. S93-S94
Author(s):  
M. BETTENDORF ◽  
F. DE ZEGHER ◽  
N. ALBERS ◽  
S. L. KAPLAN ◽  
M. M. GRUMBACH
Keyword(s):  
Gonadotropin Releasing Hormone ◽  
Gonadotropin Secretion ◽  
Releasing Hormone ◽  
Gnrh Release ◽  
Ovine Fetus

scholarly journals Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Vengala Rao Yenuganti ◽  
Dirk Koczan ◽  
Jens Vanselow
Keyword(s):  
Oleic Acid ◽  
Granulosa Cells ◽  
System Development ◽  
Circulatory System ◽  
Bioinformatic Analysis ◽  
Negative Energy ◽  
Tissue Remodelling ◽  
Gonadotropin Secretion ◽  
Genome Wide

Abstract Background Metabolic stress, as negative energy balance on one hand or obesity on the other hand can lead to increased levels of free fatty acids in the plasma and follicular fluid of animals and humans. In an earlier study, we showed that increased oleic acid (OA) concentrations affected the function of cultured bovine granulosa cells (GCs). Here, we focus on genome wide effects of increased OA concentrations. Results Our data showed that 413 genes were affected, of which 197 were down- and 216 up-regulated. Specifically, the expression of FSH-regulated functional key genes, CCND2, LHCGR, INHA and CYP19A1 and 17-β-estradiol (E2) production were reduced by OA treatment, whereas the expression of the fatty acid transporter CD36 was increased and the morphology of the cells was changed due to lipid droplet accumulation. Bioinformatic analysis revealed that associated pathways of the putative upstream regulators “FSH” and “Cg (choriogonadotropin)” were inhibited and activated, respectively. Down-regulated genes are over-represented in GO terms “reproductive structure/system development”, “ovulation cycle process”, and “(positive) regulation of gonadotropin secretion”, whereas up-regulated genes are involved in “circulatory system development”, “vasculature development”, “angiogenesis” or “extracellular matrix/structure organization”. Conclusions From these data we conclude that besides inhibiting GC functionality, increased OA levels seemingly promote angiogenesis and tissue remodelling, thus suggestively initiating a premature fulliculo-luteal transition. In vivo this may lead to impeded folliculogenesis and ovulation, and cause sub-fertility.

scholarly journals Desensitization of Pituitary Gonadotropin Secretion by Agonist-induced Inactivation of Voltage-sensitive Calcium Channels

1989 ◽  
Vol 264 (19) ◽  
pp. 10939-10942
Author(s):  
S S Stojilković ◽  
E Rojas ◽  
A Stutzin ◽  
S Izumi ◽  
K J Catt
Keyword(s):  
Calcium Channels ◽  
Gonadotropin Secretion ◽  
Pituitary Gonadotropin

A Detailed Examination of the in vivo and in vitro Effects of ACTH on Gonadotropin Secretion in the Adult Rat

1985 ◽  
Vol 40 (4) ◽  
pp. 297-302 ◽  
Author(s):  
David R. Mann ◽  
Diane Evans ◽  
Festus Edoimioya ◽  
Freja Kamel ◽  
George M. Butterstein
Keyword(s):  
Detailed Examination ◽  
Gonadotropin Secretion ◽  
Adult Rat ◽  
In Vitro Effects

Steroid control of gonadotropin secretion

1991 ◽  
Vol 40 (1-3) ◽  
pp. 417-420 ◽  
Author(s):  
G. Schaison ◽  
B. Couzinet
Keyword(s):  
Gonadotropin Secretion

Contraceptive progestins and gonadotropin secretion In vitro

1987 ◽  
Vol 27 (4-6) ◽  
pp. 995-1002 ◽  
Author(s):  
Ludwig Kiesel ◽  
Klauss Helm ◽  
Karin Bertges ◽  
Christiane Maier ◽  
Thomas Rabe ◽  
...  
Keyword(s):  
Gonadotropin Secretion
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