scholarly journals Nephrotic Syndrome with Lesion of Focal Glomerulosclerosis

2020 ◽  
Author(s):  
Keyword(s):  
Nephrotic Syndrome ◽  
Focal Glomerulosclerosis

Focal Glomerulosclerosis-like Disease with Nephrotic Syndrome in a Horse

1981 ◽  
Vol 18 (5) ◽  
pp. 692-694 ◽  
Author(s):  
H. C. Wimberly ◽  
T. T. Antonovych ◽  
R. M. Lewis
Keyword(s):  
Nephrotic Syndrome ◽  
Focal Glomerulosclerosis

The Urinary Podocyte as a Marker for the Differential Diagnosis of Idiopathic Focal Glomerulosclerosis and Minimal-Change Nephrotic Syndrome

2000 ◽  
Vol 20 (3) ◽  
pp. 175-179 ◽  
Author(s):  
Tsukasa Nakamura ◽  
Chifuyu Ushiyama ◽  
Shingo Suzuki ◽  
Masanori Hara ◽  
Noriaki Shimada ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Nephrotic Syndrome ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Focal Glomerulosclerosis

scholarly journals Antihuman immunoglobulin affinity immunoadsorption strongly decreases proteinuria in patients with relapsing nephrotic syndrome.

1998 ◽  
Vol 9 (9) ◽  
pp. 1709-1715
Author(s):  
J Dantal ◽  
Y Godfrin ◽  
R Koll ◽  
S Perretto ◽  
J Naulet ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Ex Vivo ◽  
Protein A ◽  
Affinity Column ◽  
Focal Glomerulosclerosis ◽  
Direct Role ◽  
First Time ◽  
Firm Evidence

Approximately 20 to 30% of patients with idiopathic nephrotic syndrome and focal glomerulosclerosis experience a relapse of their nephrotic syndrome after transplantation. Previously, it has been shown that ex vivo immunoadsorption on protein A strongly (although transiently) reduces proteinuria in relapsing patients. To investigate whether the factor(s) that give rise to albuminuria are bound directly to protein A in the immunoadsorption procedure or are part of a complex with Ig, four patients with relapse of focal glomerulosclerosis presenting as nephrotic syndrome after transplantation were treated, sequentially, using a (non-protein A) anti-Ig affinity column and a protein A column. This study reports that the effect on proteinuria of immunoadsorption using an anti-Ig immunoaffinity column is comparable in its magnitude and kinetics to that of immunoadsorption on protein A. The two procedures were also equally effective in depleting the relapsing patients' plasma of a factor capable of altering the albumin permselectivity of isolated glomeruli in vitro. This study demonstrates for the first time that immunoglobulins have a role in the nephrotic syndrome. In addition, the fact that the two different immunoadsorption procedures both resulted in the removal of the same putative albuminuric factor in these patients and that no autoreactivity of eluted immunoglobulins was observed on human tissues strongly suggests that the factor or factors that may be responsible for immediate nephrotic syndrome after transplantation are bound to an immunoglobulin. However, no firm evidence can be yet provided against a direct role of immunoglobulins.

Prognosis of Children With Nephrotic Syndrome

1990 ◽  
Vol 12 (5) ◽  
pp. 132-148
Keyword(s):  
Electron Microscopy ◽  
Nephrotic Syndrome ◽  
Membranoproliferative Glomerulonephritis ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Age Difference ◽  
Focal Glomerulosclerosis ◽  
Mesangial Proliferation ◽  
Collaborative Studies ◽  
Modern Era

Well before the modern era of diagnosis and management of nephrotic syndrome (characterized by proteinuria, hypoalbuminemia, edema, and hypercholesterolemia), pediatricians recognized a different, more benign form of the disorder than did internists. This age difference has been borne out by the remarkable international collaborative studies in children's renal centers. With the advent of more precise renal biopsy diagnosis by thin section and electron microscopy, pathological diagnosis now includes minimal glomerular changes, focal glomerulosclerosis, mesangial proliferation, and mesangial proliferation with focal segmental glomerulosclerosis. Eighty percent of patients with primary nephrotic syndrome or minimal change nephrotic syndrome experience symptoms before 6 years of age, but membranoproliferative glomerulonephritis rarely appears before this age.

scholarly journals LDL-adsorption ameliorates drug-resistant nephrotic syndrome due to focal glomerulosclerosis.

1992 ◽  
Vol 25 (12) ◽  
pp. 1363-1368 ◽  
Author(s):  
Masatomo Yashiro ◽  
Eri Muso ◽  
Munehiro Matsushima ◽  
Ryouichi Nagura ◽  
Kenji Sawanishi
Keyword(s):  
Nephrotic Syndrome ◽  
Drug Resistant ◽  
Focal Glomerulosclerosis

scholarly journals PULSE METHYLPREDNISOLONE (MP) THERAPY OF NEPHROTIC SYNDROME WITH FOCAL GLOMERULOSCLEROSIS (FGS)

1984 ◽  
Vol 18 ◽  
pp. 368A-368A
Author(s):  
Vivian M Reznik ◽  
Bruce M Tune ◽  
William R Griswold ◽  
Martha Vasquez ◽  
Stanley A Mendoza
Keyword(s):  
Nephrotic Syndrome ◽  
Focal Glomerulosclerosis ◽  
Pulse Methylprednisolone
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