scholarly journals Choroid Plexus Epithelium of the Lateral Ventricle

2020 ◽  
Author(s):  
Keyword(s):  
Choroid Plexus ◽  
Lateral Ventricle ◽  
Choroid Plexus Epithelium

Active transport of chloride by lateral ventricle choroid plexus of the rat

1985 ◽  
Vol 249 (4) ◽  
pp. F470-F477 ◽  
Author(s):  
Q. R. Smith ◽  
C. E. Johanson
Keyword(s):  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Active Transport ◽  
Lateral Ventricle ◽  
Bath Temperature ◽  
Methyl Sulfate ◽  
Choroid Plexus Epithelium ◽  
Adult Rat ◽  
Cation Substitutions ◽  
K Transport

The nature of Cl transport and its relation to Na and K transport were analyzed in adult rat lateral ventricle choroid plexus incubated in cerebrospinal fluid (CSF) medium at 37 degrees C and PCO2 = 30 mmHg. In synthetic CSF (extracellular Cl [( Cl]o) = 130 mM), the intracellular Cl [( Cl]i) was three times that estimated for passive distribution. Choroid plexus [Cl]i was not determined by Donnan distribution because [Cl]i remained constant at approximately 50 mM while the [K]i/[K]o ratio was varied 10-fold by drugs and cation substitutions. A [Cl]i/[Cl]o ratio of approximately 0.38 was found when [Cl]o was varied from 15 to 130 mM by isosmotic replacement of Cl with methyl sulfate or isethionate. However, the [Cl]i/[Cl]o ratio increased to greater than 1.0 when [Cl]o was lowered below 5 mM. Reduction in bath temperature to 15 degrees C (CSF PCO2 = 50 mmHg) increased both [Cl]i/[Cl]o and [HCO3]i/[HCO3]o to approximately 0.6. SITS, an inhibitor of Cl-HCO3 transport, reduced [Cl]i by 18 mM, decreasing the [Cl]i/[Cl]o ratio close to the equilibrium value. In contrast, neither furosemide (10(-3) M) nor low CSF [Na]o (3 mM) reduced Cl accumulation. It is concluded that uphill movement of Cl into choroid plexus epithelium occurs primarily by Cl-HCO3 antiport and not by Na-Cl symport.

Organization of tight junctions in the choroid plexus epithelium

1978 ◽  
Vol 36 (2) ◽  
pp. 336-337
Author(s):  
B. Van Deurs ◽  
J. K. Koehler
Keyword(s):  
Choroid Plexus ◽  
Present Report ◽  
Freeze Fracture ◽  
Barrier Properties ◽  
Cell Junctions ◽  
Structural Basis ◽  
Apical Surface ◽  
Choroid Plexus Epithelium ◽  
Solid Nitrogen ◽  
Special Composition

The choroid plexus epithelium constitutes a blood-cerebrospinal fluid (CSF) barrier, and is involved in regulation of the special composition of the CSF. The epithelium is provided with an ouabain-sensitive Na/K-pump located at the apical surface, actively pumping ions into the CSF. The choroid plexus epithelium has been described as “leaky” with a low transepithelial resistance, and a passive transepithelial flux following a paracellular route (intercellular spaces and cell junctions) also takes place. The present report describes the structural basis for these “barrier” properties of the choroid plexus epithelium as revealed by freeze fracture.Choroid plexus from the lateral, third and fourth ventricles of rats were used. The tissue was fixed in glutaraldehyde and stored in 30% glycerol. Freezing was performed either in liquid nitrogen-cooled Freon 22, or directly in a mixture of liquid and solid nitrogen prepared in a special vacuum chamber. The latter method was always used, and considered necessary, when preparations of complementary (double) replicas were made.

scholarly journals T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0150945 ◽  
Author(s):  
Nathalie Strazielle ◽  
Rita Creidy ◽  
Christophe Malcus ◽  
José Boucraut ◽  
Jean-François Ghersi-Egea
Keyword(s):  
T Lymphocytes ◽  
Choroid Plexus ◽  
Choroid Plexus Epithelium ◽  
The Brain

Fetal lateral ventricle choroid plexus cysts: The dilemma of amniocentesis

1992 ◽  
Vol 38 (4) ◽  
pp. 343-343
Author(s):  
R Achiron ◽  
G Barkai ◽  
M Bat-Miriam Katznelson ◽  
S Mashiach
Keyword(s):  
Choroid Plexus ◽  
Lateral Ventricle

Primary carcinoma of the choroid plexus in the lateral ventricle

1991 ◽  
Vol 36 (4) ◽  
pp. 294-299 ◽  
Author(s):  
Masayuki Matsuda ◽  
Sachiko Uzura ◽  
Satoshi Nakasu ◽  
Jyoji Handa
Keyword(s):  
Choroid Plexus ◽  
Lateral Ventricle ◽  
Primary Carcinoma

Inflammatory pseudotumor of the choroid plexus

2008 ◽  
Vol 108 (2) ◽  
pp. 365-369 ◽  
Author(s):  
Kosuke Miyahara ◽  
Kazuhiko Fujitsu ◽  
Saburo Yagishita ◽  
Yasunori Takemoto ◽  
Teruo Ichikawa ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Choroid Plexus ◽  
Lateral Ventricle ◽  
Inflammatory Pseudotumor ◽  
Clinicopathological Characteristics ◽  
Histopathological Diagnosis ◽  
Gait Disorder ◽  
Resonance Imaging ◽  
Left Lateral Ventricle

✓The authors report a case of inflammatory pseudotumor that developed in the choroid plexus of the lateral ventricle. The patient was a 73-year-old man who had undergone surgery for rectal cancer at another hospital 5 years earlier. He was referred to the authors' department, with his chief symptoms consisting of disorientation, right hemiparesis, and gait disorder that had gradually developed during the preceding month. On computed tomography and magnetic resonance imaging, a well-demarcated and homogeneously contrasted tumorous lesion was noted in the region from the trigone to the medial wall of the inferior horn of the left lateral ventricle. Expansion of the inferior horn was also evident. Intraoperative findings showed that the tumor originated from the choroid plexus of the lateral ventricle, and the histopathological diagnosis was inflammatory pseudotumor. There are only 4 previously reported cases of inflammatory pseudotumor that developed in the choroid plexus; the authors review the literature and discuss the clinicopathological characteristics of the condition.

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