scholarly journals CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine

2020 ◽  
Author(s):  
Keyword(s):  
Fusion Protein ◽  
Tetanus Toxoid ◽  
T Helper ◽  
Plasmid Vaccine ◽  
Helper Epitope ◽  
Dna Plasmid

scholarly journals Tetanus Toxoid carrier protein induced T-helper cell responses upon vaccination of middle-aged adults

Vaccine ◽  
2017 ◽  
Vol 35 (42) ◽  
pp. 5581-5588 ◽  
Author(s):  
Marieke van der Heiden ◽  
Aafke Duizendstra ◽  
Guy A.M. Berbers ◽  
Annemieke M.H. Boots ◽  
Anne-Marie Buisman
Keyword(s):  
Tetanus Toxoid ◽  
T Helper Cell ◽  
Helper Cell ◽  
Carrier Protein ◽  
T Helper ◽  
Middle Aged ◽  
Cell Responses ◽  
Middle Aged Adults

AttenuatedListeria monocytogenescarrier strains can deliver an HIV-1 gp120 T helper epitope to MHC class II-restricted human CD4+ T cells

1998 ◽  
Vol 28 (6) ◽  
pp. 1807-1814 ◽  
Author(s):  
Carlos A. Guzmán ◽  
Daniele Saverino ◽  
Eva Medina ◽  
Daniela Fenoglio ◽  
Birgit Gerstel ◽  
...  
Keyword(s):  
T Cells ◽  
Mhc Class Ii ◽  
Cd4 T Cells ◽  
Class Ii ◽  
T Helper ◽  
Helper Epitope ◽  
Hiv 1

Influence of the T-helper epitope on the titre and affinity of antibodies to B-cell epitopes after co-immunization

1993 ◽  
Vol 30 (11) ◽  
pp. 961-968 ◽  
Author(s):  
D.Michael Shaw ◽  
Carolynne M. Stanley ◽  
Charalambos D. Partidos ◽  
Michael W. Steward
Keyword(s):  
B Cell ◽  
T Helper ◽  
B Cell Epitopes ◽  
Helper Epitope

scholarly journals Safety Profile of the Merck Human Immunodeficiency Virus-1 Clade B gag DNA Plasmid Vaccine With and Without Adjuvants

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Erin K. Quirk ◽  
Elizabeth L. Brown ◽  
Randi Y. Leavitt ◽  
Robin Mogg ◽  
Devan V. Mehrotra ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Adverse Events ◽  
Dna Vaccine ◽  
Low Grade ◽  
Clade B ◽  
Priming Phase ◽  
Plasmid Vaccine ◽  
Immunodeficiency Virus ◽  
Dna Plasmid ◽  
Phosphate Buffered Saline

Abstract The immunogenicity results from 3 phase I trials of the Merck DNA human immunodeficiency virus (HIV) vaccine have previously been reported. Because preventive DNA vaccine strategies continue to be leveraged for diverse infections, the safety and tolerability results from these studies can inform the field moving forward, particularly regarding adverse reactions and adjuvants. No serious vaccine-related adverse events were reported during the 3-dose priming phase. Pain at the injection site was more common with adjuvanted formulations than with the phosphate-buffered saline diluent alone. Febrile reactions were usually low grade. Although the AlPO4 or CRL1005 adjuvants used in these studies did not significantly enhance the immunogenicity of the DNA vaccine, adverse events were numerically more common with adjuvanted formulations than without adjuvants.

Synthesis of Branched Oxime-Linked Peptide Mimetics of the MUC1 Containing a Universal T-Helper Epitope

2004 ◽  
Vol 10 (24) ◽  
pp. 6353-6360 ◽  
Author(s):  
Gaëlle-Anne Cremer ◽  
Nicole Bureaud ◽  
Dominique Lelièvre ◽  
Véronique Piller ◽  
Friedrich Piller ◽  
...  
Keyword(s):  
Peptide Mimetics ◽  
T Helper ◽  
Helper Epitope
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