scholarly journals Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified

2020 ◽  
Author(s):  
Keyword(s):  
Acute Leukemia ◽  
Not Otherwise Specified ◽  
Mixed Phenotype Acute Leukemia ◽  
Mixed Phenotype

scholarly journals Venetoclax and Decitabine for T/Myeloid Mixed-Phenotype Acute Leukemia Not Otherwise Specified (MPAL NOS)

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Heather Klocke ◽  
Zhao Ming Dong ◽  
Craig O’Brien ◽  
Nicholas Burwick ◽  
Robert E. Richard ◽  
...  
Keyword(s):  
Stem Cell ◽  
Acute Leukemia ◽  
Stem Cell Transplant ◽  
Treatment Guidelines ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Not Otherwise Specified ◽  
Mixed Phenotype Acute Leukemia ◽  
One Year ◽  
Mixed Phenotype

T/myeloid mixed-phenotype acute leukemia not otherwise specified (MPAL NOS) is an uncommon and aggressive leukemia without well-established treatment guidelines, particularly when relapsed. Venetoclax plus a hypomethylating agent offers a promising option in this situation since studies support its use in both acute myeloid and, albeit with fewer data to date, acute T-cell-lymphoblastic leukemias. We report the successful eradication of T/myeloid MPAL NOS relapsed after allogeneic stem cell transplant with venetoclax plus decitabine. A consolidative allogeneic stem cell transplant from a second donor was subsequently performed, and the patient remained without evidence of disease more than one year later. Further investigation is indicated to evaluate venetoclax combined with hypomethylating agents and/or other therapies for the management of T/myeloid MPAL NOS.

scholarly journals The First Case of Non-leukemic Sarcoma Composed of Mixed-phenotype Acute Leukemia, B/myeloid, Not Otherwise Specified

2018 ◽  
Vol 57 (8) ◽  
pp. 1155-1158 ◽  
Author(s):  
Teruhito Takakuwa ◽  
Takahiko Nakane ◽  
Masahiko Ohsawa ◽  
Joji Nagasaki ◽  
Yasutaka Aoyama ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Not Otherwise Specified ◽  
First Case ◽  
Mixed Phenotype Acute Leukemia ◽  
Mixed Phenotype

scholarly journals Correction to: Mixed-phenotype acute leukemia characteristics: first report from Iran

2021 ◽  
Author(s):  
Behzad Poopak ◽  
Adnan Khosravi ◽  
Gholamreza Bahoush-Mehdiabadi ◽  
Tahereh Madani ◽  
Elahe Khodadi ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
First Report ◽  
Mixed Phenotype Acute Leukemia ◽  
Mixed Phenotype

scholarly journals Genomic characterization of chromosome translocations in patients with T/myeloid mixed-phenotype acute leukemia

2017 ◽  
Vol 59 (5) ◽  
pp. 1231-1238 ◽  
Author(s):  
Aparna Pallavajjala ◽  
Daehwan Kim ◽  
Tongbin Li ◽  
Gabriel Ghiaur ◽  
Richard J. Jones ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Chromosome Translocations ◽  
Mixed Phenotype Acute Leukemia ◽  
Genomic Characterization ◽  
Mixed Phenotype
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