scholarly journals Pituitary Gland Chromophobe Adenoma

2020 ◽  
Author(s):  
1971 ◽  
Vol 34 (6) ◽  
pp. 726-729 ◽  
Author(s):  
Bronson S. Ray ◽  
Russell H. Patterson

✓ Between 1950 and 1969, 165 operations were performed on 146 patients for the treatment of chromophobe adenoma of the pituitary gland unassociated with either acromegaly or Cushing's syndrome. The over-all operative mortality was 1.2%, and no deaths occurred in 138 cases operated on for the first time. In 106 of the patients who had not received prior treatment, vision was improved in 80% of cases and returned to normal in 50%. In the group of patients whose initial treatment was surgery, postoperative radiation therapy was administered in one-half of the cases. The rate of recurrence was 8% in those who received radiation and 22% in those who did not. Recurrence of symptoms within less than 1 year often was due to a hemorrhagic cyst which could be treated better by reoperation than by radiation therapy.


1969 ◽  
Vol 62 (4) ◽  
pp. 647-652 ◽  
Author(s):  
J. Lindholm ◽  
P. Rasmussen ◽  
O. Korsgaard

ABSTRACT Two patients with concurrent Cushing's disease and chromophobe adenoma of the pituitary gland are presented. In one case the tumour was present before adrenalectomy, in the other it was not recognized until after adrenalectomy. The characteristic symptoms and findings are described – including the results of corticotrophin determinations in the blood. Some aspects of the treatment of Cushing's disease are discussed.


1965 ◽  
Vol 48 (1) ◽  
pp. 72-80 ◽  
Author(s):  
H. H. Bassøe ◽  
H. Gadeholt ◽  
K. Ronold ◽  
K. F. Støa

ABSTRACT A thirty-nine years old woman with primary amenorrhoea and increased excretion of gonadotrophins, developed a chromophobe adenoma in the pituitary gland. Only a few years before she died, the diagnosis of Cushing's disease was made which progressed despite hypophysectomy. Evidence is given for the conclusion, that the patient suffered from ovarian dysgenesis, which secondarily led to hyperfunction and tumour formation of the pituitary gland and also to development of Cushing's disease. It is concluded that patients with hypogonadism should be observed for pituitary tumour formation, and that adequate substitution therapy may prevent formation of pituitary tumours.


1973 ◽  
Vol 10 (3) ◽  
pp. 232-237 ◽  
Author(s):  
F. A. Zaki ◽  
S.-K. Liu

Chromophobe adenoma was diagnosed in the pituitary gland of an 11-year-old domestic shorthaired cat. Histologically, the tumor consisted of a mass of cells with scant sinusoidal arrangement and connective tissue stroma and few blood vessels. In areas the neoplastic cells contained large vacuoles that occupied the entire cytoplasm and pushed the nuclei aside.


Neurology ◽  
1964 ◽  
Vol 14 (6) ◽  
pp. 537-537 ◽  
Author(s):  
J. J. Kepes ◽  
T. J. Fritzlen

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