scholarly journals Immunodeficiency due to a late component of complement deficiency

2020 ◽  
Author(s):  
Keyword(s):  
Complement Deficiency ◽  
Late Component

scholarly journals SLE-like and sicca symptoms in late component (C9) complement deficiency.

1987 ◽  
Vol 46 (2) ◽  
pp. 153-155 ◽  
Author(s):  
M Sugimoto ◽  
M Nishikai ◽  
A Sato ◽  
Y Suzuki ◽  
M Nihei ◽  
...  
Keyword(s):  
Complement Deficiency ◽  
Late Component ◽  
Sicca Symptoms

Effect of noradrenaline on an early and a late component of the myocardial contraction

1978 ◽  
Vol 305 (1) ◽  
pp. 65-74 ◽  
Author(s):  
K. Seibel ◽  
E. Karema ◽  
K. Takeya ◽  
M. Reiter
Keyword(s):  
Myocardial Contraction ◽  
Late Component

Complement deficiency ameliorates smoke-induced nasal damage

2009 ◽  
Vol 141 (3) ◽  
pp. P110-P110
Author(s):  
Kara Davis ◽  
Rodney Schlosser ◽  
Carl Atkinson
Keyword(s):  
Complement Deficiency

Early manifestation and recognition of C2 complement deficiency in the form of pyogenic infection in infancy

2003 ◽  
Vol 39 (4) ◽  
pp. 274-277 ◽  
Author(s):  
J Litzman ◽  
T Freiberger ◽  
D Bartonkova ◽  
M Vlkova ◽  
V Thon ◽  
...  
Keyword(s):  
Complement Deficiency ◽  
Pyogenic Infection ◽  
Early Manifestation

scholarly journals Bottom-up saliency and top-down learning in the primary visual cortex of monkeys

2018 ◽  
Vol 115 (41) ◽  
pp. 10499-10504 ◽  
Author(s):  
Yin Yan ◽  
Li Zhaoping ◽  
Wu Li
Keyword(s):  
Visual Cortex ◽  
Primary Visual Cortex ◽  
Detection Task ◽  
Late Response ◽  
Late Component ◽  
Neuronal Responses ◽  
Top Down ◽  
Bottom Up ◽  
Response Component ◽  
Orientation Contrast

Early sensory cortex is better known for representing sensory inputs but less for the effect of its responses on behavior. Here we explore the behavioral correlates of neuronal responses in primary visual cortex (V1) in a task to detect a uniquely oriented bar—the orientation singleton—in a background of uniformly oriented bars. This singleton is salient or inconspicuous when the orientation contrast between the singleton and background bars is sufficiently large or small, respectively. Using implanted microelectrodes, we measured V1 activities while monkeys were trained to quickly saccade to the singleton. A neuron’s responses to the singleton within its receptive field had an early and a late component, both increased with the orientation contrast. The early component started from the outset of neuronal responses; it remained unchanged before and after training on the singleton detection. The late component started ∼40 ms after the early one; it emerged and evolved with practicing the detection task. Training increased the behavioral accuracy and speed of singleton detection and increased the amount of information in the late response component about a singleton’s presence or absence. Furthermore, for a given singleton, faster detection performance was associated with higher V1 responses; training increased this behavioral–neural correlate in the early V1 responses but decreased it in the late V1 responses. Therefore, V1’s early responses are directly linked with behavior and represent the bottom-up saliency signals. Learning strengthens this link, likely serving as the basis for making the detection task more reflexive and less top-down driven.

scholarly journals DEFICIENCY OF THE SIXTH COMPONENT OF COMPLEMENT IN RABBITS WITH AN INHERITED COMPLEMENT DEFECT

1966 ◽  
Vol 124 (4) ◽  
pp. 773-785 ◽  
Author(s):  
Klaus Rother ◽  
Ursula Rother ◽  
Hans J. Müller-Eberhard ◽  
Ulf R. Nilsson
Keyword(s):  
Complement System ◽  
Hemolytic Activity ◽  
Complement Deficiency ◽  
Rabbit Serum ◽  
Partial Purification ◽  
Normal Rabbit Serum ◽  
Chemically Modified ◽  
System A ◽  
Inactive Form

A strain of rabbits with an inherited complement deficiency was shown to lack the sixth component of the hemolytic complement system. A method was elaborated for the partial purification of this component from normal rabbit serum. Upon injection of partially purified rabbit C'6 into C'6-deficient animals, an antibody was obtained which specifically inhibited the hemolytic activity of C'6. The data suggest that C'6-deficient serum either lacks the C'6 molecule or contains it in a chemically modified and inactive form.

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