Conjunctival Hemorrhage

2020 ◽  
Author(s):  
Keyword(s):  
Conjunctival Hemorrhage

Sub-conjunctival Hemorrhage Following a Bout of Cough: A Harbinger of Underlying Bleeding Diathesis

2017 ◽  
Vol 84 (10) ◽  
pp. 804-805
Author(s):  
Lakshmi Madhumathi Marimuthu ◽  
Raksha Ranjan ◽  
Venkatesh Chandrasekaran ◽  
Barath Jagadisan ◽  
Niranjan Biswal
Keyword(s):  
Bleeding Diathesis ◽  
Conjunctival Hemorrhage

scholarly journals Sutureless and glue free conjunctival auto grafting after pterygium excision

2017 ◽  
Vol 10 (2) ◽  
pp. 36-38
Author(s):  
M.K. Goswami ◽  
Md Asaduzzaman
Keyword(s):  
Metabolic Disorders ◽  
Operation Time ◽  
Fibrin Clot ◽  
Effective Treatment Modality ◽  
Department Of Ophthalmology ◽  
Recurrent Pterygium ◽  
The Mean ◽  
Pterygium Excision ◽  
Conjunctival Hemorrhage

Background and objectives: Suture or glue has been used to secure the conjunctival auto graft after excision of the pterygium. Recently, auto grafting using patient’s own blood as a bioadhesive to secure the graft in position has been described by several authors. Therefore, the present study was undertaken to determine the outcome of excision of pterygium and sutureless conjunctival auto graft using patients’ own blood as a bioadhesive.Methods: Patients with primary and recurrent pterygium attending the Department of Ophthalmology of Bangladesh Institute of Research, Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) hospital from March 2014 to July 2015 were included in the study. Pterygium was excised and conjunctival auto graft was applied. Grafts were secured to the pterygium excision area with auto blood fibrin clot. All patients were examined after 48 hr and followed for 1, 4 and 12 weeks for graft dislodgement, sub-conjunctival hemorrhage, graft recession, graft edema and recurrence of pterygium.Results: A total of 35 primary and 2 recurrent pterygium cases were included in the study. The mean operation time was 15±1 minutes. Out of 37 eyes 5 (13.5%) had subconjunctival hemorrhage and 2 (5.4%) had graft recession and edema after 48hrs of operation. At 3 months follow up, 2 cases (5.4%) of graft recession and no case of recurrence of pterygium was found.Conclusion: Pterygium excision and conjunctival auto graft without sutures appears to be an effective treatment modality for primary and recurrent pterygium with no additional cost.IMC J Med Sci 2016; 10(2): 36-38

Correlation of imatinib plasma trough concentrations with adverse reaction in Chinese gastrointestinal stromal tumors patients.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 11034-11034
Author(s):  
Yanzhe Xia ◽  
Sile Chen ◽  
Shirong Cai ◽  
Yulong He ◽  
Xinhua Zhang
Keyword(s):  
Adverse Reaction ◽  
Steady State ◽  
Gastrointestinal Stromal Tumors ◽  
High Volume ◽  
Muscle Cramp ◽  
Imatinib Treatment ◽  
Stromal Tumors ◽  
Liquid Chromatography Tandem Mass ◽  
Grade 3 ◽  
Conjunctival Hemorrhage

11034 Background: Imatinib is the standard treatment for patients of Gastrointestinal Stromal Tumors (GISTs), but the intra- and inter-variability of imatinib plasma trough concentration (Cmin) are significant. Few studies investigated the association between Cmin and adverse reaction in Chinese GIST patients. The distribution of imatinib Cmin in different doses and the correlation of imatinib Cmin with adverse reaction in Chinese GIST patients from a high-volume center were evaluated. Methods: From 1 Jul 2017 to 31 Dec 2018, a total of 400 patients who were under imatinib treatment were prospectively studied. All patients’ informed consents were obtained. Steady state plasma samples were obtained from patients at least administrating 1 month treatment who were taking imatinib 100 to 800 mg/d, with continuous similar timing of daily dosage for more than 14 days. The adverse reaction was recorded during regular follow-up at out-patient clinic, and blood sample was collected 22±2 hours to the next dosage of imatinib. Liquid chromatography tandem mass spectrometry was applied to determine the concentration. Adverse reaction grades were referred to CTCAE v4.0. Results: A total of 368 patients who followed the same dose of imatinib with good compliance, and having at least 2 times of tests were investigated. The imatinib Cmin was 384±53 ng/mL, 776±337 ng/mL, 986±327 ng/mL, 1078±498 ng/mL, 1309±712 ng/mL, 1620±469 ng/mL, 2117±597 ng/mL and 3844±987 ng/mL in patients who were administrated with 100 mg/d (n = 3), 200 mg/d (n = 15), 250 mg/d (n = 5), 300 mg/d (n = 80), 400 mg/d (n = 235), 500 mg/d (n = 3), 600 mg/d (n = 22) and 800 mg/d (n = 5), respectively. In correlation analysis, imatinib Cmin was significantly correlated with periorbital and limbs edema (p < 0.01), anemia (p < 0.01) and rush (p < 0.01), correlated with diarrhea and conjunctival hemorrhage but not significant. Much higher Cmin was observed in severe adverse reaction (≥ grade 3) of periorbital and limbs edema and rash. There was no correlation between Cmin with leukopenia, nausea, vomiting, muscle cramp or hepatobiliary disorders. Conclusions: In Chinese GIST patients, imatinib Cmin at steady state was seems higher than Western populations previous reported, especially in higher doses (≥600 mg/d). Imatinib Cmin was correlated with anemia, periorbital and limbs edema, diarrhea and conjunctival hemorrhage, suggesting that imatinib Cmin monitor might be considered when patients were subjected to severe adverse reactions which were caused by excessive imatinib plasma concentration.

scholarly journals An outbreak of Coxsackievirus A6 infection in adults of a collective unit, China, 2019

2019 ◽  
Author(s):  
Yumeng Gao ◽  
Guangyuan Ma ◽  
Yong Xiao ◽  
Qun Cai ◽  
Yujun Chen ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Molecular Data ◽  
Respiratory Pathogen ◽  
Nucleic Acid Detection ◽  
Nasopharyngeal Swab ◽  
Vp1 Gene ◽  
Coxsackievirus A6 ◽  
Laboratory Results ◽  
Enterovirus Type ◽  
Conjunctival Hemorrhage

Abstract Background: Outbreaks/epidemic caused by Coxsackievirus A6 have been reported continuously since 2008. However, outbreaks caused by Coxsackievirus A6 infection in adults of a collective unit have not been reported. Methods: The nasopharyngeal swab specimens were collected to extract the total nucleic acid (DNA/RNA). The pathogen was determined using 22 respiratory pathogen nucleic acid detection kits. The VP1 gene of this pathogen was amplified and sequenced. Sequence alignment and analysis were performed using Bioedit. The gene phylogenetic tree was constructed with MEGA software. Results: The factory emerged patients in succession from the February 14 and reached the peak on the 18th. The main symptoms were rash, ocular conjunctival hemorrhage, fever and sore throat. A total of 19 workers had symptoms in this factory up to March 31, 2019, giving an attack rate of 8.26%. The laboratory results showed that Coxsackievirus A6 was the enterovirus type causing this outbreak. The risk of illness was 7.37 times higher taking bath in bathroom than that of not taking bath (95% CI 1.67, 32.79). Conclusions: Epidemiologic and molecular data indicated Coxsackievirus A6 as the etiology of this outbreak of adults in a collective unit, a risk factor for the spread was taking bath in the bathroom of the factory.

A 7-Year-Old Girl With Periorbital Edema, Ecchymosis, and Conjunctival Hemorrhage

2016 ◽  
Vol 170 (10) ◽  
pp. 1021
Author(s):  
Elizabeth M. Keating ◽  
Debra L. Palazzi
Keyword(s):  
Periorbital Edema ◽  
Conjunctival Hemorrhage

scholarly journals A case of SFTS coinfected with E. coli bacteremia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyungdon Lee ◽  
Woo Young Choi ◽  
Choon Mee Kim ◽  
Na-Ra Yun ◽  
Dong-Min Kim ◽  
...  
Keyword(s):  
Liver Function ◽  
Foley Catheter ◽  
Gastrointestinal Symptoms ◽  
Hemorrhagic Fever ◽  
Case Presentation ◽  
E Coli ◽  
First Case ◽  
Low Blood Pressure ◽  
Severe Fever ◽  
Conjunctival Hemorrhage

Abstract Background Severe fever thrombocytopenia syndrome virus (SFTSV) is the causative agent of severe fever thrombocytopenia syndrome (SFTS). SFTS is an emerging infectious disease, characterized by high fever, gastrointestinal symptoms, leukopenia, thrombocytopenia, and a high mortality rate. Until now, little importance has been given to the association of SFTS with leukocytosis and bacterial co-infection. Case presentation A 51-year old man visited our hospital with fever and low blood pressure. He was a farmer by occupation and often worked outdoors. He had a Foley catheter inserted due to severe BPH. Laboratory tests revealed thrombocytopenia, elevated liver function, and elevated CRP levels. He had marked leukocytosis, proteinuria, hematuria, and conjunctival hemorrhage. Initially, we thought that the patient was suffering from hemorrhagic fever with renal syndrome (HFRS). However, we confirmed SFTS through PCR and increasing antibody titer. However, his blood culture also indicated E. coli infection. Conclusion SFTS displays characteristics of fever, thrombocytopenia, elevated liver function, and leukocytopenia. We described a case of SFTS with leukocytosis due to coinfection with E. coli. Since patients with SFTS usually have leukocytopenia, SFTS patients with leukocytosis are necessarily evaluated for other causes of leukocytosis. Here, we report the first case of an SFTS with concurrent E. coli bacteremia.

scholarly journals Slit lamp photography for objective assessment of topical eye disorders

2022 ◽  
Vol 7 (4) ◽  
pp. 648-654
Author(s):  
A B Biradar ◽  
Arun Das ◽  
Adeeb A
Keyword(s):  
Objective Assessment ◽  
Smart Phone ◽  
Research Society ◽  
Evidence Based ◽  
Slit Lamp ◽  
Eye Disorders ◽  
Scientific Analysis ◽  
Quantitative Data Analysis ◽  
Clinical Conditions ◽  
Conjunctival Hemorrhage

Evidence based scientific studies has weightage, when they are presented with quantitative data analysis. Documentation and parametric analysis has become an integral part of present day research. Any publications or write-ups without explanation through standard parameters are not appreciated by the research society. In Ophthalmology assessment of various parameters through photography is a debatable issue. Affordability for higher end diagnostic / OPD instruments may not be feasible for all. In such a scenario, here is an attempt made to standardize the slit lamp photography with a smart phone and its scientific analysis for evaluating clinical conditions like sub-conjunctival hemorrhage, etc. This technique can become a tool for assessment and response of the therapies as well as an important tool to seek help from higher centers. Various add-on benefits in research, limitation and scope for further evaluation also being discussed.

Case 1: A Term Neonate with Conjunctival Hemorrhage, Ecchymoses, and Umbilical Hematoma

NeoReviews ◽  
2021 ◽  
Vol 22 (2) ◽  
pp. e118-e121
Author(s):  
Lt Col Abhishek Pandey ◽  
Lt Col Ramar Praveen ◽  
Col G. Shridhar
Keyword(s):  
Term Neonate ◽  
Conjunctival Hemorrhage

scholarly journals Profile of pediatric ocular trauma in mid western hilly region of Nepal

1970 ◽  
Vol 4 (1) ◽  
pp. 134-137 ◽  
Author(s):  
S Dulal ◽  
JB Ale ◽  
YD Sapkota
Keyword(s):  
Medical Records ◽  
Ocular Trauma ◽  
Ocular Injury ◽  
Hilly Region ◽  
Open Globe ◽  
History Of ◽  
Ocular Injuries ◽  
The Himalaya ◽  
Open Globe Injuries ◽  
Conjunctival Hemorrhage

Introduction: Majority of blinding ocular injuries can be prevented. Objective: To describe the epidemiology of ocular trauma in children. Material and methods: A retrospective review of medical records of the patients aged below 16 years who attended the Himalaya Eye Hospital, Pokhara with history of ocular injury. Results: Of 6,829 pediatric patients, 554 (8.1 %) had ocular trauma. The ocular trauma was more prevalent (38.1 %) in the age group of 5 – 10 years followed by 10-15 years (16.6 %). The boys (62 % vs 38 %) were more prone to ocular trauma than girls (RR = 1.7 and 95 % CI = 1.41 - 2.02). Of 554 ocular injuries, 32 (5.8 %) were open globe injuries. Sub-conjunctival hemorrhage was the commonest presenting finding in 96 (17.3 %) subjects. Forty-seven (8.5 %) of them attended the hospital after 15 days of injury. Home was the most common place for trauma (n =204, 36.8%), followed by playground (n = 140, 25.3 %). Conclusion: Children between the ages of 5-10 years are most vulnerable to ocular trauma. Home is the commonest place for ocular injury followed by playground. By adopting some common safety factors or by reducing the ocular injury risks factor, ocular trauma can be greatly reduced. DOI: http://dx.doi.org/10.3126/nepjoph.v4i1.5865 NEPJOPH 2012; 4(1): 134-137

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