scholarly journals Schistosoma mekongi

2020 ◽  
Author(s):  
Keyword(s):  
Schistosoma Mekongi

scholarly journals Identification of Low Molecular Weight Proteins and Peptides from Schistosoma mekongi Worm, Egg and Infected Mouse Sera

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 559
Author(s):  
Tipparat Thiangtrongjit ◽  
Nattapon Simanon ◽  
Poom Adisakwattana ◽  
Yanin Limpanont ◽  
Phiraphol Chusongsang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Infected Mouse ◽  
In Silico ◽  
Limited Information ◽  
Schistosoma Mekongi ◽  
River Region ◽  
Precursor Proteins ◽  
Peptide Profiles ◽  
Low Sensitivity ◽  
Proteins And Peptides

Schistosoma mekongi is found in the lower Mekong river region and causes schistosomiasis. Low sensitivity of diagnosis and development of drug resistance are problems to eliminate this disease. To develop novel therapies and diagnostics for S. mekongi, the basic molecular biology of this pathogen needs to be explored. Bioactive peptides have been reported in several worms and play important roles in biological functions. Limited information is available on the S. mekongi peptidome. Therefore, this study aimed to identify S. mekongi peptides using in silico transcriptome mining and mass spectrometry approaches. Schistosoma peptide components were identified in adult worms, eggs, and infected mouse sera. Thirteen neuropeptide families were identified using in silico predictions from in-house transcriptomic databases of adult S. mekongi worms. Using mass spectrometry approaches, 118 peptides (from 54 precursor proteins) and 194 peptides (from 86 precursor proteins) were identified from adult worms and eggs, respectively. Importantly, eight unique peptides of the S. mekongi ubiquitin thioesterase, trabid, were identified in infected mouse sera 14, 28, and 56 days after infection. This protein may be a potential target for diagnosis of schistosomiasis. The S. mekongi peptide profiles determined in this study could be used for further drug and diagnostic development.

Schistosoma mekongi infection in a leiomyosarcoma of the small bowel: A case report

1992 ◽  
Vol 23 (4) ◽  
pp. 471-473 ◽  
Author(s):  
Ruben A. Cuesta ◽  
Yao Tek Kaw ◽  
Mazen S. Duwaji
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Schistosoma Mekongi

scholarly journals Control of Schistosoma mekongi in Cambodia: results of eight years of control activities in the two endemic provinces

2007 ◽  
Vol 101 (1) ◽  
pp. 34-39 ◽  
Author(s):  
M. Sinuon ◽  
R. Tsuyuoka ◽  
D. Socheat ◽  
P. Odermatt ◽  
H. Ohmae ◽  
...  
Keyword(s):  
Schistosoma Mekongi

scholarly journals Transcriptomic analysis of male and female Schistosoma mekongi adult worms

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Orawan Phuphisut ◽  
Pravech Ajawatanawong ◽  
Yanin Limpanont ◽  
Onrapak Reamtong ◽  
Supaporn Nuamtanong ◽  
...  
Keyword(s):  
Transcriptomic Analysis ◽  
Male And Female ◽  
Schistosoma Mekongi

scholarly journals Elimination of Schistosomiasis Mekongi from Endemic Areas in Cambodia and the Lao People’s Democratic Republic: Current Status and Plans

2019 ◽  
Vol 4 (1) ◽  
pp. 30 ◽  
Author(s):  
Virak Khieu ◽  
Somphou Sayasone ◽  
Sinuon Muth ◽  
Masashi Kirinoki ◽  
Sakhone Laymanivong ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Snail Host ◽  
Current Status ◽  
Separate Species ◽  
Lao People’S Democratic Republic ◽  
Infected People ◽  
Lao People's Democratic Republic ◽  
Schistosoma Mekongi ◽  
Challenge Control ◽  
Endemic Areas

The areas endemic for schistosomiasis in the Lao People's Democratic Republic and in Cambodia were first reported 50 and 60 years ago, respectively. However, the causative parasite Schistosoma mekongi was not recognized as a separate species until 1978. The infection is distributed along a limited part of the Mekong River, regulated by the focal distribution of the intermediate snail host Neotricula aperta. Although more sensitive diagnostics imply a higher figure, the current use of stool examinations suggests that only about 1500 people are presently infected. This well-characterized setting should offer an exemplary potential for the elimination of the disease from its endemic areas; yet, the local topography, reservoir animals, and a dearth of safe water sources make transmission control a challenge. Control activities based on mass drug administration resulted in strong advances, and prevalence was reduced to less than 5% according to stool microscopy. Even so, transmission continues unabated, and the true number of infected people could be as much as 10 times higher than reported. On-going control activities are discussed together with plans for the future.

Schistosoma mekongi: The in vitro effect of praziquantel and artesunate on the adult fluke

2006 ◽  
Vol 113 (1) ◽  
pp. 16-23 ◽  
Author(s):  
Wannee Jiraungkoorskul ◽  
Somphong Sahaphong ◽  
Prasert Sobhon ◽  
Suda Riengrojpitak ◽  
Niwat Kangwanrangsan
Keyword(s):  
Adult Fluke ◽  
Schistosoma Mekongi ◽  
Vitro Effect

scholarly journals False-Positive Plasmodium falciparum Histidine-Rich Protein 2 Immunocapture Assay Results for Acute Schistosomiasis Caused by Schistosoma mekongi: Table 1.

2011 ◽  
Vol 49 (6) ◽  
pp. 2331-2332 ◽  
Author(s):  
Eyal Leshem ◽  
Nathan Keller ◽  
Daphna Guthman ◽  
Tamar Grossman ◽  
Michal Solomon ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
False Positive ◽  
Schistosoma Mekongi
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