scholarly journals Neural Prosthesis

2020 ◽  
Author(s):  
Keyword(s):  
Neural Prosthesis

Fabrication of Nanoporous IrO2/Ir Films for Bioelectrode and Neural Prosthesis Applications

2018 ◽  
Vol 14 (4) ◽  
pp. 778-785
Author(s):  
Po-Chun Chen ◽  
Tsai-Wei Chung ◽  
Yu-Lun Cheng
Keyword(s):  
Neural Prosthesis

scholarly journals The Neurochip BCI: Towards a Neural Prosthesis for Upper Limb Function

2006 ◽  
Vol 14 (2) ◽  
pp. 187-190 ◽  
Author(s):  
A. Jackson ◽  
C.T. Moritz ◽  
J. Mavoori ◽  
T.H. Lucas ◽  
E.E. Fetz
Keyword(s):  
Upper Limb ◽  
Neural Prosthesis ◽  
Limb Function ◽  
Upper Limb Function

An Experimental Vestibular Neural Prosthesis: Design and Preliminary Results With Rhesus Monkeys Stimulated With Modulated Pulses

2013 ◽  
Vol 60 (6) ◽  
pp. 1685-1692 ◽  
Author(s):  
Kaibao Nie ◽  
L. Ling ◽  
S. M. Bierer ◽  
C. R. S. Kaneko ◽  
A. F. Fuchs ◽  
...  
Keyword(s):  
Rhesus Monkeys ◽  
Prosthesis Design ◽  
Neural Prosthesis ◽  
Preliminary Results

Quantifying the Accuracy of a Motion Detecting Neural Prosthesis

2020 ◽  
Author(s):  
Martin L. Tanaka ◽  
Premkumar Subbukutti ◽  
David Hudson ◽  
Kimberly Hudson ◽  
Pablo Valenzuela ◽  
...  
Keyword(s):  
Motion Capture ◽  
Gait Cycle ◽  
Neural Prosthesis ◽  
Average Error ◽  
Camera Motion ◽  
Motion Capture System ◽  
General Shape ◽  
Neural Connections ◽  
Measurement Units ◽  
The Brain

Abstract The neural prosthesis under development is designed to improve gait in people with muscle weakness. The strategy is to augment impaired or damaged neural connections between the brain and the muscles that control walking. This third-generation neural prosthesis contains triaxial inertial measurement units (IMUs - accelerometers, gyroscopes, and processing chip) to measure body segment position and force sensitive resistors placed under the feet to detect ground contact. A study was conducted to compare the accuracy of the neural prosthesis using a traditional camera motion capture system as a reference. The IMUs were found to accurately represent the amplitude of the gait cycle components and generally track the motion. However, there are some differences in phase, with the IMUs lagging the actual motion. Phase lagged by about 10 degrees in the ankle and by about 5 degrees in the knee. Error of the neural prosthesis varied over the gait cycle. The average error for the ankle, knee and hip were 6°, 8°, and 9°, respectively. Testing showed that the neural prosthesis was able to capture the general shape of the joint angle curves when compared to a commercial camera motion capture system. In the future, measures will be taken to reduce lag in the gyroscope and reduce jitter in the accelerometer so that data from both sensors can be combination to obtain more accurate readings.

scholarly journals Long-term use of a neural prosthesis in progressive paralysis

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Yoji Okahara ◽  
Kouji Takano ◽  
Masahiro Nagao ◽  
Kiyohiko Kondo ◽  
Yasuo Iwadate ◽  
...  
Keyword(s):  
Neural Prosthesis

scholarly journals A novel neural prosthesis providing long-term electrocorticography recording and cortical stimulation for epilepsy and brain-computer interface

2019 ◽  
Vol 130 (4) ◽  
pp. 1166-1179 ◽  
Author(s):  
Pantaleo Romanelli ◽  
Marco Piangerelli ◽  
David Ratel ◽  
Christophe Gaude ◽  
Thomas Costecalde ◽  
...  
Keyword(s):  
Nonhuman Primate ◽  
Large Scale ◽  
Brain Activity ◽  
Threshold Value ◽  
Time Span ◽  
Cortical Stimulation ◽  
Neural Prosthesis ◽  
Lower Limbs ◽  
Custom Made

OBJECTIVEWireless technology is a novel tool for the transmission of cortical signals. Wireless electrocorticography (ECoG) aims to improve the safety and diagnostic gain of procedures requiring invasive localization of seizure foci and also to provide long-term recording of brain activity for brain-computer interfaces (BCIs). However, no wireless devices aimed at these clinical applications are currently available. The authors present the application of a fully implantable and externally rechargeable neural prosthesis providing wireless ECoG recording and direct cortical stimulation (DCS). Prolonged wireless ECoG monitoring was tested in nonhuman primates by using a custom-made device (the ECoG implantable wireless 16-electrode [ECOGIW-16E] device) containing a 16-contact subdural grid. This is a preliminary step toward large-scale, long-term wireless ECoG recording in humans.METHODSThe authors implanted the ECOGIW-16E device over the left sensorimotor cortex of a nonhuman primate (Macaca fascicularis), recording ECoG signals over a time span of 6 months. Daily electrode impedances were measured, aiming to maintain the impedance values below a threshold of 100 KΩ. Brain mapping was obtained through wireless cortical stimulation at fixed intervals (1, 3, and 6 months). After 6 months, the device was removed. The authors analyzed cortical tissues by using conventional histological and immunohistological investigation to assess whether there was evidence of damage after the long-term implantation of the grid.RESULTSThe implant was well tolerated; no neurological or behavioral consequences were reported in the monkey, which resumed his normal activities within a few hours of the procedure. The signal quality of wireless ECoG remained excellent over the 6-month observation period. Impedance values remained well below the threshold value; the average impedance per contact remains approximately 40 KΩ. Wireless cortical stimulation induced movements of the upper and lower limbs, and elicited fine movements of the digits as well. After the monkey was euthanized, the grid was found to be encapsulated by a newly formed dural sheet. The grid removal was performed easily, and no direct adhesions of the grid to the cortex were found. Conventional histological studies showed no cortical damage in the brain region covered by the grid, except for a single microscopic spot of cortical necrosis (not visible to the naked eye) in a region that had undergone repeated procedures of electrical stimulation. Immunohistological studies of the cortex underlying the grid showed a mild inflammatory process.CONCLUSIONSThis preliminary experience in a nonhuman primate shows that a wireless neuroprosthesis, with related long-term ECoG recording (up to 6 months) and multiple DCSs, was tolerated without sequelae. The authors predict that epilepsy surgery could realize great benefit from this novel prosthesis, providing an extended time span for ECoG recording.

Interfacing the body’s own sensing receptors into neural prosthesis devices

1999 ◽  
Vol 7 (6) ◽  
pp. 393-399 ◽  
Author(s):  
Morten Haugland ◽  
Thomas Sinkjær
Keyword(s):  
Neural Prosthesis
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