scholarly journals Intralobar Nephrogenic Rest

2020 ◽  
Author(s):  
Keyword(s):  
Nephrogenic Rest

Single-Nucleotide Polymorphism in WT1 Gene in a Hyperplastic Intralobar Nephrogenic Rest With Botryoid Protrusion

Urology ◽  
2010 ◽  
Vol 76 (1) ◽  
pp. 149-152 ◽  
Author(s):  
Kentaro Mizuno ◽  
Yutaro Hayashi ◽  
Keiichi Tozawa ◽  
Shoichiro Iwatsuki ◽  
Yoshiyuki Kojima ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Wt1 Gene ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Nephrogenic Rest

Genome-wide loss of maternal alleles in a nephrogenic rest and Wilms' tumour from a BWS patient

1995 ◽  
Vol 95 (6) ◽  
Author(s):  
PaulR. Hoban ◽  
Jim Heighway ◽  
GavinR.M. White ◽  
Bart Baker ◽  
Jackie Gardner ◽  
...  
Keyword(s):  
Wilms Tumour ◽  
Genome Wide ◽  
Nephrogenic Rest

GIANT HYPERPLASTIC NEPHROGENIC REST IN A SOLITARY KIDNEY PRESENTING AS AN ANGIOMYOLIPOMA IN A CHILD

1998 ◽  
Vol 159 (6) ◽  
pp. 2114-2115
Author(s):  
ZACHARY V. ZUNIGA ◽  
ANDREW J. KIRSCH ◽  
JOEL ROSEN ◽  
STEPHEN A. ZDERIC
Keyword(s):  
Solitary Kidney ◽  
Nephrogenic Rest

Primary Extrarenal Nephrogenic Rest

2002 ◽  
Vol 168 (4 Part 1) ◽  
pp. 1529-1529 ◽  
Author(s):  
Stephen Bennett ◽  
William Defoor ◽  
Eugene Minevich
Keyword(s):  
Nephrogenic Rest

Bilateral Nephroblastic Tumors and a Complex Renal Vascular Anomaly in a Patient With a Mosaic RASopathy: Novel Histopathologic Features and Molecular Insights

2021 ◽  
pp. 109352662098650
Author(s):  
Jonathan C Slack ◽  
Marie-Anne Bründler ◽  
Caitlin A Chang ◽  
Renee Perrier ◽  
Lucie Lafay-Cousin ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Wilms Tumor ◽  
Vascular Anomaly ◽  
Driver Mutations ◽  
Bone Lesions ◽  
Activating Mutations ◽  
Nephrogenic Rest ◽  
Sclerotic Bone Lesions ◽  
Renal Vascular ◽  
Nephrogenic Rests

Mosaic RASopathies are an emerging group of disorders characterized by mosaic or post-zygotic activating mutations in genes of the RAS/MAPKinase signaling pathway. The phenotype is highly variable, ranging from limited or localized forms to cases with a syndromic presentation with extensive or multiorgan involvement, and also overlaps with other mosaic disorders. While there are several reports of malignancies in patients with mosaic RASopathies, specifically rhabdomyosarcoma and transitional urothelial carcinoma, the lifetime risk and molecular mechanisms that lead to the development of malignancies remain unclear. We report a 22-month-old boy with a somatic RASopathy due to an underlying KRAS p.G12D mutation who presented with a large unilateral epidermal nevus, asymmetric lower limb overgrowth with lytic and sclerotic bone lesions, capillary malformation, bilateral nephrogenic rests and Wilms tumors, and a novel complex renal vascular anomaly that resembles Fibro-Adipose Vascular Anomaly (FAVA). This report further expands the phenotypic spectrum of somatic RASopathies, and discusses the potential phenotypic and pathogenetic overlap with PIK3CA-related overgrowth disorders, specifically CLOVES. The occurrence of a secondary cancer hotspot mutation ( FBXW7 p.R479G ) in the Wilms tumor, but not the associated nephrogenic rest, moreover suggests that additional driver mutations are involved in the development of Wilms tumor in somatic overgrowth disorders.

Nephrogenic Rest Associated with a Mesoblastic Nephroma—What does it Tell Us?

1995 ◽  
Vol 15 (3) ◽  
pp. 469-475 ◽  
Author(s):  
Gordan M. Vujanic ◽  
Bengt Sandstedt ◽  
Frederique Dijoud ◽  
Dieter Harms ◽  
Jan F. M. Delemarre
Keyword(s):  
Mesoblastic Nephroma ◽  
Nephrogenic Rest

Lumbosacral Ectopic Nephrogenic Rest Unassociated With Spinal Dysraphism

2004 ◽  
Vol 28 (10) ◽  
pp. 1389-1392 ◽  
Author(s):  
Marcelo G Horenstein ◽  
Elizabeth A Manci ◽  
Andrew B Walker ◽  
Louis P Dehner
Keyword(s):  
Spinal Dysraphism ◽  
Nephrogenic Rest
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