scholarly journals Mouse Protein

2020 ◽  
Author(s):  
Keyword(s):  
Genomics ◽  
2005 ◽  
Vol 85 (3) ◽  
pp. 285-296 ◽  
Author(s):  
Claudia Gutjahr ◽  
Derek Murphy ◽  
Angelika Lueking ◽  
Andrea Koenig ◽  
Michal Janitz ◽  
...  

1995 ◽  
Vol 15 (7) ◽  
pp. 3487-3495 ◽  
Author(s):  
M P Draper ◽  
C Salvadore ◽  
C L Denis

The CCR4 protein from Saccharomyces cerevisiae is a component of a multisubunit complex that is required for the regulation of a number of genes in yeast cells. We report here the identification of a mouse protein (mCAF1 [mouse CCR4-associated factor 1]) which is capable of interacting with and binding to the yeast CCR4 protein. The mCAF1 protein was shown to have significant similarity to proteins from humans, Caenorhabditis elegans, Arabidopsis thaliana, and S. cerevisiae. The yeast gene (yCAF1) had been previously cloned as the POP2 gene, which is required for expression of several genes. Both yCAF1 (POP2) and the C. elegans homolog of CAF1 were shown to genetically interact with CCR4 in vivo, and yCAF1 (POP2) physically associated with CCR4. Disruption of the CAF1 (POP2) gene in yeast cells gave phenotypes and defects in transcription similar to those observed with disruptions of CCR4, including the ability to suppress spt10-enhanced ADH2 expression. In addition, yCAF1 (POP2) when fused to LexA was capable of activating transcription. mCAF1 could also activate transcription when fused to LexA and could functionally substitute for yCAF1 in allowing ADH2 expression in an spt10 mutant background. These data imply that CAF1 is a component of the CCR4 protein complex and that this complex has retained evolutionarily conserved functions important to eukaryotic transcription.


SciVee ◽  
2007 ◽  
Author(s):  
J. Fink ◽  
Rajith Aturaliya ◽  
Melissa Davis ◽  
Fasheng Zhang ◽  
Kelly Hanson ◽  
...  

Gene ◽  
1996 ◽  
Vol 170 (2) ◽  
pp. 181-188 ◽  
Author(s):  
Marcus J. Korth ◽  
Christopher N. Lyons ◽  
Marlene Wambach ◽  
Michael G. Katze

1996 ◽  
Vol 32 (1-3) ◽  
pp. 96-98 ◽  
Author(s):  
Margareta Zechmeister-Machhart ◽  
Peter Hufnagl ◽  
Pavel Uhrin ◽  
Jianjun Xu ◽  
Margarethe Geiger ◽  
...  

1994 ◽  
Vol 74 (2) ◽  
pp. 135-142 ◽  
Author(s):  
Deshun Lu ◽  
Dyann K. Schmidel ◽  
George L. Long

FEBS Letters ◽  
2016 ◽  
Vol 590 (20) ◽  
pp. 3606-3615 ◽  
Author(s):  
Rie Kusano ◽  
Kousuke Fujita ◽  
Yasuharu Shinoda ◽  
Yuko Nagaura ◽  
Hiroshi Kiyonari ◽  
...  

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