Dolastatin 10 | ScienceGate

Faculty Opinions recommendation of Combinatorial strategies by marine cyanobacteria: symplostatin 4, an antimitotic natural dolastatin 10/15 hybrid that synergizes with the coproduced HDAC inhibitor largazole.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1163920.624558 ◽

2009 ◽

Author(s):

David Newman

Keyword(s):

Hdac Inhibitor ◽

Marine Cyanobacteria ◽

Dolastatin 10

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The Conformational Properties of (-)-Dolastatin 10, a Powerful Antineoplastic Agent

Topics in Molecular Organization and Engineering - Properties and Chemistry of Biomolecular Systems ◽

10.1007/978-94-011-0822-5_17 ◽

1994 ◽

pp. 205-209

Author(s):

P. Fantucci ◽

E. Mattioli ◽

T. Marino ◽

N. Russo

Keyword(s):

Antineoplastic Agent ◽

Conformational Properties ◽

Dolastatin 10

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Conformational analysis of dolastatin 10 and dolastatin 15 by molecular mechanics and molecular dynamics

10.1063/1.47720 ◽

1995 ◽

Author(s):

P. Fantucci ◽

T. Marino ◽

N. Russo ◽

A. M. Villa

Keyword(s):

Molecular Dynamics ◽

Conformational Analysis ◽

Molecular Mechanics ◽

Dolastatin 10

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ChemInform Abstract: Dolastatins. Part 24. Synthesis of (-)-Dolastatin 10. X-Ray Molecular Structure of N,N-Dimethylvalyl-valyl-dolaisoleuine tert-Butyl Ester.

ChemInform ◽

10.1002/chin.199633212 ◽

2010 ◽

Vol 27 (33) ◽

pp. no-no

Author(s):

G. R. PETTIT ◽

J. K. SRIRANGAM ◽

S. B. SINGH ◽

M. D. WILLIAMS ◽

D. L. HERALD ◽

...

Keyword(s):

Molecular Structure ◽

Butyl Ester ◽

X Ray ◽

Tert Butyl ◽

Dolastatin 10

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A new efficient synthesis of (S)-dolaphenine ((S)-2-phenyl-1-(2-thiazolyl)ethylamine), the C-terminal unit of dolastatin 10

Tetrahedron ◽

10.1016/s0040-4020(01)88264-8 ◽

1992 ◽

Vol 48 (35) ◽

pp. 7251-7264 ◽

Cited By ~ 40

Author(s):

Naoko Irako ◽

Yasumasa Hamada ◽

Takayuki Shioiri

Keyword(s):

Efficient Synthesis ◽

Terminal Unit ◽

Dolastatin 10

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Direct Photoaffinity Labeling by Dolastatin 10 of the Amino-terminal Peptide of β-Tubulin Containing Cysteine 12

Journal of Biological Chemistry ◽

10.1074/jbc.m402110200 ◽

2004 ◽

Vol 279 (29) ◽

pp. 30731-30740 ◽

Cited By ~ 19

Author(s):

Ruoli Bai ◽

David G. Covell ◽

George F. Taylor ◽

John A. Kepler ◽

Terry D. Copeland ◽

...

Keyword(s):

Photoaffinity Labeling ◽

Amino Terminal ◽

Dolastatin 10 ◽

Β Tubulin

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Microtubule depolymerization in Uromyces appendiculatus by three new antineoplastic drugs: combretastatin A-4, dolastatin 10 and halichondrin B

Mycological Research ◽

10.1017/s0953756297004930 ◽

1998 ◽

Vol 102 (3) ◽

pp. 378-382 ◽

Cited By ~ 4

Author(s):

Robert W. Roberson ◽

Bruce Tucker ◽

George R. Pettit

Keyword(s):

Uromyces Appendiculatus ◽

Antineoplastic Drugs ◽

Microtubule Depolymerization ◽

Halichondrin B ◽

Dolastatin 10

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Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification

Cancer Chemotherapy and Pharmacology ◽

10.1007/s002800050931 ◽

1999 ◽

Vol 43 (6) ◽

pp. 507-515 ◽

Cited By ~ 41

Author(s):

Gregory P. Kalemkerian ◽

Xiaolan Ou ◽

Mohammed R. Adil ◽

Rita Rosati ◽

M. Monir Khoulani ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

Induction Of Apoptosis ◽

In Vivo Induction ◽

Dolastatin 10

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Phase II trials of dolastatin-10 in advanced pancreaticobiliary cancers

Investigational New Drugs ◽

10.1007/s10637-005-2909-x ◽

2005 ◽

Vol 23 (5) ◽

pp. 489-493 ◽

Cited By ~ 40

Author(s):

Hedy L. Kindler ◽

Peter K. Tothy ◽

Robert Wolff ◽

Richard A. McCormack ◽

James L. Abbruzzese ◽

...

Keyword(s):

Phase Ii ◽

Phase Ii Trials ◽

Dolastatin 10

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Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc

The Prostate ◽

10.1002/(sici)1097-0045(19980215)34:3<175::aid-pros4>3.0.co;2-h ◽

1998 ◽

Vol 34 (3) ◽

pp. 175-181 ◽

Cited By ~ 21

Author(s):

Timothy Turner ◽

William H. Jackson ◽

George R. Pettit ◽

Alan Wells ◽

Andrew S. Kraft

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells ◽

Dolastatin 10 ◽

Marine Shell

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