scholarly journals Myeloid Progenitor Cell Count

2020 ◽  
Author(s):  
Keyword(s):  
Cell Count ◽  
Progenitor Cell ◽  
Myeloid Progenitor ◽  
Myeloid Progenitor Cell

scholarly journals Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0229593 ◽  
Author(s):  
Anna A. Schönherz ◽  
Julie Støve Bødker ◽  
Alexander Schmitz ◽  
Rasmus Froberg Brøndum ◽  
Lasse Hjort Jakobsen ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Progenitor Cell ◽  
Cell Subset ◽  
Prognostic Impact ◽  
Gene Signatures ◽  
Myeloid Progenitor ◽  
Myeloid Progenitor Cell ◽  
Acute Myeloid

scholarly journals Acute leukemia associated with the t(4;11) chromosome rearrangement: ultrastructural and immunologic characteristics

Blood ◽  
1982 ◽  
Vol 60 (6) ◽  
pp. 1321-1331 ◽  
Author(s):  
JL Parkin ◽  
DC Arthur ◽  
CS Abramson ◽  
RW McKenna ◽  
JH Kersey ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Clinical Features ◽  
Progenitor Cell ◽  
Chromosome Rearrangement ◽  
Poor Response ◽  
Response To Therapy ◽  
Leukemic Cells ◽  
Myeloid Progenitor ◽  
Hla Dr ◽  
Myeloid Progenitor Cell

Abstract The acute leukemia associated with the t(4;11) chromosome rearrangement is characterized by relatively consistent clinical features: occurrence primarily in young individuals, hyperleukocytosis, and poor response to therapy. This study describes the morphological, ultrastructural, and immunologic characteristics of the leukemic cells from ten patients with this type of leukemia. The morphological features of the leukemic blasts vary from lymphoid-appearing to monocytic. Ultrastructurally and cytochemically, some of the lymphoid-appearing blasts possess features of myeloid origin. The immunologic phenotype is characteristically E- SIg- CALLA- BA-1- BA-2+ HLA-DR+ and TdT+. These findings suggest that the t(4;11)-associated acute leukemia represents a proliferation of an early myeloid progenitor cell.

Malaria toxins from P. chabaudi chabaudi AS and P. berghei ANKA cause dyserythropoiesis in C57BL/6 mice

Parasitology ◽  
1997 ◽  
Vol 115 (5) ◽  
pp. 467-474 ◽  
Author(s):  
W. RUDIN ◽  
V. QUESNIAUX ◽  
N. FAVRE ◽  
G. BORDMANN
Keyword(s):  
Severe Malaria ◽  
Plasmodium Berghei ◽  
Intraperitoneal Injection ◽  
Proliferative Activity ◽  
Progenitor Cell ◽  
Myeloid Progenitor ◽  
Flow Cytometric ◽  
Myeloid Progenitor Cell ◽  
Colony Assays ◽  
Daily Intraperitoneal Injection

The lack of correlation between parasitaemia and anaemia in severe malaria indicates that factors in addition to schizont rupture or erythrophagocytosis contribute to anaemia. We asked whether malaria toxin (MT) from Plasmodium berghei or P. chabaudi might impair erythropoiesis. Daily intraperitoneal injection of MT into C57BL/6 mice induced a transient reduction of RBC values by 25–30% after about 2 weeks, followed by increased haematopoiesis in the spleen as compared to mice receiving uninfected RBC preparations. There was a 3 (P. berghei) to 8-fold (P. chabaudi) increase of total proliferative activity in the spleen. Flow cytometric analyses showed that this was accompanied by some differentiation of TER-119 positive erythroid cells and of Gr-1 positive myeloid cells. Erythroid and myeloid progenitor cell-derived colony assays confirmed these results and revealed an increase in the number of CFU-E ([les ]200-fold), BFU-E ([les ]10-fold) and CFU-GM ([les ]20-fold) in the spleen of MT treated mice, as compared to controls.

Altered Growth Factor Response in Myeloid Progenitor Cell Mutants Derived after Retroviral Insertlonal Mutagenesis

1996 ◽  
pp. 307-319
Author(s):  
Christine Laker ◽  
Jutta Friel ◽  
Marie-Joseé Franz ◽  
Manuela Baccarini ◽  
Wolfram Ostertag ◽  
...  
Keyword(s):  
Growth Factor ◽  
Progenitor Cell ◽  
Myeloid Progenitor ◽  
Myeloid Progenitor Cell
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