scholarly journals Porfimer Sodium

2020 ◽  
Author(s):  
Keyword(s):  
Porfimer Sodium

Analysis of photosensitivity in Japanese cancer-bearing patients receiving photodynamic therapy with porfimer sodium (PhotofrinTM)

2001 ◽  
Vol 17 (5) ◽  
pp. 241-243 ◽  
Author(s):  
Shin-Ichi Moriwaki ◽  
Junko Misawa ◽  
Yasushi Yoshinari ◽  
Ichiro Yamada ◽  
Masahiro Takigawa ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Porfimer Sodium

Clinical Pharmacokinetics of the PDT Photosensitizers Porfimer Sodium (Photofrin), 2-[1-Hexyloxyethyl]-2-Devinyl Pyropheophorbide-a (Photochlor) and 5-ALA-Induced Protoporphyrin IX

2006 ◽  
Vol 38 (5) ◽  
pp. 439-444 ◽  
Author(s):  
David A. Bellnier ◽  
William R. Greco ◽  
Gregory M. Loewen ◽  
Hector Nava ◽  
Allan R. Oseroff ◽  
...  
Keyword(s):  
Protoporphyrin Ix ◽  
Clinical Pharmacokinetics ◽  
Porfimer Sodium ◽  
Pyropheophorbide A

Optimizing Photodynamic Therapy Outcomes By the Determination of Mucosal Porfimer Sodium Concentration in Patients with Barrett's Dysplasia and Carcinoma

2008 ◽  
Vol 67 (5) ◽  
pp. AB179 ◽  
Author(s):  
Kanwar R. Gill ◽  
Seth A. Gross ◽  
Linda R. Jones ◽  
Norris W. Preyer ◽  
Marquitta V. Scott ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Sodium Concentration ◽  
Therapy Outcomes ◽  
Porfimer Sodium

Disinfection of radicular dentin using Riboflavin, Rose Bengal, Curcumin, and Porfimer sodium on extrusion bond strength of fiber post to radicular dentin

2021 ◽  
pp. 102625
Author(s):  
Sami A Alturaiki ◽  
Ahmed A. Bamanie ◽  
Mohammed A. Albulowey ◽  
Abdullah A. Al Daafas ◽  
Abdullah Almalki ◽  
...  
Keyword(s):  
Bond Strength ◽  
Rose Bengal ◽  
Fiber Post ◽  
Porfimer Sodium

Porfimer sodium-mediated photodynamic therapy in patients with head and neck squamous cell carcinoma

2020 ◽  
Vol 29 ◽  
pp. 101627 ◽  
Author(s):  
Seiji Hosokawa ◽  
Goro Takahashi ◽  
Ken-ichi Sugiyama ◽  
Satoru Takebayashi ◽  
Jun Okamura ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Porfimer Sodium

scholarly journals Synthesis and photodynamic activity of diaryl-porphyrins characterized by the presence of nitro groups

2006 ◽  
Vol 10 (11) ◽  
pp. 1319-1326 ◽  
Author(s):  
Stefano Banfi ◽  
Enrico Caruso ◽  
Emanuele Fieni ◽  
Loredana Buccafurni ◽  
Marzia Bruna Gariboldi ◽  
...  
Keyword(s):  
Colon Adenocarcinoma ◽  
Aromatic Aldehydes ◽  
Human Colon ◽  
Halogen Lamp ◽  
Porfimer Sodium ◽  
Standard Procedures ◽  
Photodynamic Activity ◽  
Phenyl Rings ◽  
Meso Position

A panel of nitro substituted 5,15-diaryl-porphyrins, featuring nitro groups either on the phenyl rings or on one of the two free meso-positions, was synthesized. In the former category, compounds 5-(3-nitrophenyl)-15-phenylporphyrin, 5,15-di(3-nitrophenyl)porphyrin and 5-(4-nitrophenyl)-15-phenylporphyrin were obtained following standard procedures by reacting dipyrromethane and aromatic aldehydes. In the latter category, porphyrins 10-nitro-5,15-diphenylporphyrin, 10-nitro-5-(3-methoxyphenyl)-15-phenylporphyrin and 10-nitro-5,15-di(3-methoxyphenyl)porphyrin were generated by nitration of 5,15-diarylporphyrins with trifluoroacetic acid/sodium nitrite under particularly mild conditions. The new molecules bearing one or two nitro-groups were tested as photosensitizers during in vitro experiments on a human colon adenocarcinoma cell line (HCT116), and their effects were compared with those induced by temoporfin, porfimer sodium and by some previously published electron-rich diarylporphyrins. The results, expressed as IC50 values obtained by the MTT test following 24 h incubation with the photosensitizers and 2 h irradiation with a 500 W tungsten-halogen lamp, indicate that the presence of an electron withdrawing substituent, on a meso-position, decreases the photodynamic activity of the compound. Conversely, 5-(3-nitrophenyl)-15-phenylporphyrin, a non symmetrically substituted diarylporphyrin bearing both one electron-deficient and one lipophilic moiety, resulted in high phototoxic activity.

scholarly journals Evaluation of porfimer sodium fluorescence for measuring tissue transformation

Cancer ◽  
1993 ◽  
Vol 72 (10) ◽  
pp. 3068-3077 ◽  
Author(s):  
David H. Crean ◽  
Charles Liebow ◽  
Remedios B. Penetrante ◽  
Thomas S. Mang
Keyword(s):  
Porfimer Sodium
Sign in / Sign up

Export Citation Format

Share Document