scholarly journals Echinacea Extract

2020 ◽  
Author(s):  
Keyword(s):  
Echinacea Extract

Echinacea purpurea L. in children: safety, tolerability, compliance, and clinical effectiveness in upper respiratory tract infectionsThis article is one of a selection of papers published in this special issue (part 2 of 2) on the Safety and Efficacy of Natural Health Products.

2007 ◽  
Vol 85 (11) ◽  
pp. 1195-1199 ◽  
Author(s):  
Paul Richard Saunders ◽  
Fraser Smith ◽  
Read Weaver Schusky
Keyword(s):  
Respiratory Tract ◽  
Clinical Effectiveness ◽  
Echinacea Purpurea ◽  
Natural Health Products ◽  
Upper Respiratory Tract ◽  
Natural Health ◽  
Health Products ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Echinacea Extract

Echinacea purpurea (L.) Moench was mistakenly taken from North America to Germany in 1939 where it was cultivated and various extractions were prepared and subsequently used to treat upper respiratory tract infections. Parents often administer Echinacea to their children, but safety data on the use of Echinacea in Canadian children is lacking. A screening history, physical examination, and daily record of symptoms from an initial visit through to a the follow-up visit 13 days later were used to increase patient safety. Each subject was administered an aerial part Echinacea extract. The dose was based on age (2.5 mL three times per day for children aged 2–5 years, and 5 mL two times per day for children aged 6–12 years) and administered for 10 days in an open-label trial. A rating scale was used to measure tolerance to the treatment. We assessed the safety and compliance of use of the Echinacea extract by measuring the amount of extract returned at the end of the study, having the parents complete and return a daily symptom diary, and recording the subjects’ use of other natural health products or medications during the trial. Clinical effectiveness of the Echinacea extract could not be accurately assessed because of the small trial size and because the extract had been administered when some of the subjects had an upper respiratory tract infection that had begun 1 or more days prior to the study; however, each subject’s symptoms improved. No allergic or adverse reaction occurred and no safety issues arose.

CYP3A4 inhibitory compounds from Echinacea extract (Echinaforce®)

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
M Modarai ◽  
A Suter ◽  
A Kortenkamp ◽  
M Heinrich
Keyword(s):  
Inhibitory Compounds ◽  
Echinacea Extract

Double‐blind placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract

2019 ◽  
Vol 34 (3) ◽  
pp. 660-668
Author(s):  
József Haller ◽  
Laszlo Krecsak ◽  
János Zámbori
Keyword(s):  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Echinacea Extract

The role of Echinacea extract to protect the damage effects of gammaradiation on some biochemical constituents in male albino rats

2016 ◽  
Author(s):  
A. G. Ahmed ◽  
Nahed Abdelaziz ◽  
H. M. El-Shennawy ◽  
A. N. El Shahat ◽  
R. G. Hamza
Keyword(s):  
Tissue Damage ◽  
Male Rats ◽  
Albino Rats ◽  
Protective Effects ◽  
Severe Damage ◽  
Biochemical Alterations ◽  
Radiation Induced ◽  
Effects Of Radiation ◽  
Echinacea Extract

The present study was designed to determine the possible protective effects of E. purpurea extracts (EPE) against gamma (g-) radiation exposure (6Gy) induced biochemical alterations and oxidative tissue damage (liver and testes) in male rats given EPE (100 mg/kg/day for 8 weeks) prior to g-irradiation. It has been found that g-irradiation led to hepatic and testicular oxidative stress with concomitant increase in liver function enzymes. Serum lipid profile and hormone level has also been found altered. Rats dosed with EPE before exposure to g-rays showed significantly less severe damage and remarkable improvement in all of the measured parameters when compared to irradiated rats. It could be concluded that EPE attenuates the deleterious effects of radiation-induced biochemical disorders and tissue damage (liver and testes).

Pharmacokinetics and immunomodulatory effect of lipophilic Echinacea extract formulated in softgel capsules

2015 ◽  
Vol 97 ◽  
pp. 8-14 ◽  
Author(s):  
Stefano Dall’Acqua ◽  
Beatrice Perissutti ◽  
Iztok Grabnar ◽  
Rossella Farra ◽  
Manola Comar ◽  
...  
Keyword(s):  
Immunomodulatory Effect ◽  
Echinacea Extract

scholarly journals SOLUTION OF THE PROBLEM OF TREATMENT OF NEUROPENICAL AFT MERCULAR SHELL OF THE ORAL CAVITY

2018 ◽  
Vol 14 (4) ◽  
pp. 19-23 ◽  
Author(s):  
Карен Караков ◽  
Karen Karakov ◽  
Эмилия Хачатурян ◽  
Emilia Khachaturyan ◽  
Татьяна Власова ◽  
...  
Keyword(s):  
Treatment Regimen ◽  
General Scheme ◽  
Pain Syndrome ◽  
Well Being ◽  
Traditional Treatment ◽  
Mucous Membranes ◽  
Injection Techniques ◽  
Homeopathic Preparation ◽  
And Control ◽  
Echinacea Extract

Importance. A comparative analysis of the application of methods for the treatment of neuropenic aft mucous membranes with the use of injection techniques of a homeopathic preparation, which includes ascorbic acid and echinacea extract, has been carried out. stimulating oral immunity, helps faster epithelization of neutropenic aft on the oral mucosa Objectives ― evaluate the effectiveness of using the composition of homeopathic dosage forms in the general scheme of treatment of neuropenic aft. Methods. Under our supervision there were 10 patients aged from 18 to 60 years with a diagnosis of neuropenic aphthae. All surveyed were divided into two groups: main (5 people) and control (5 people). In the main group, patients received therapy according to the generally accepted scheme: oxygen therapy, applications for neuropenic aphtha keratoplasty in combination with anesthesin. Under the base, the aphta was injected with homeopathic preparation No. 7. Then the afta was left under the film with solcoseryl. Results. It has been established that its use allows one to achieve epithelization of aphtha in a shorter period, to prolong the remission of the disease, to arrest the pain syndrome. Clinical well-being came already on the 5th visit, pain syndrome and inflammation phenomena on the mucous membrane of the tongue were removed at the 3rd visit. When applying the traditional method of treatment, clinical well-being was achieved at the 10th visit. Conclusions.The combination of the traditional treatment regimen with the use of homeopathic medicine No. 7 provides a high therapeutic effect, accelerates the process of rehabilitation of the patient and prolongs the periods of remission within 12 months. The data we obtained allow us to introduce this treatment regimen into the clinic of therapeutic dentistry for the conservative treatment of neuropenic aft.

scholarly journals Einsatz von Echinacea-Extrakt bei tragenden und säugenden Sauen

2005 ◽  
Vol 48 (3) ◽  
pp. 270-282
Author(s):  
G. Kuhn ◽  
K. Ender ◽  
R. Thomann ◽  
M. Tuchscherer ◽  
A. Tuchscherer ◽  
...  
Keyword(s):  
Growth Performance ◽  
Treatment Time ◽  
Immunoglobulin A ◽  
Echinacea Purpurea ◽  
Carcass Quality ◽  
Feed Supplement ◽  
Reactive Protein ◽  
Liquid Feed ◽  
Echinacea Extract

Abstract. Title of the paper: Application of Echinacea-extract in pregnant and suckled sows In an experiment with thirteen sows (echinacea: n = 6; control: n = 7), the influence of Echinacea purpurea treatment of pregnant and suckled sows on immune system, health status, growth performance, and carcass quality of the offspring (echinacea: n = 69; control: n = 79) was investigated. Echinacea was given as liquid feed supplement during the whole pregnant and suckling period of sows in six intervalls (5 days of treatment, followed by 2 weeks of break, respectively). During the treatment time the daily dosage per sow in echinacea-group was 0.125 ml preparation of echinacea extract (incl. solution)/kg body weight. To measure the concentrations of immunoglobulin G (IgG), immunoglobulin A (IgA) and C-reactive protein (CRP) in serum, blood samples were taken by punction of V. cava cranialis (sows and piglets) at different times. The treatment of sows resulted in immunostimulatory effects both in sows and piglets with highest changes in peripartal period. In one day old piglets, the concentrations of IgG, IgA and CRP were significantly increased in echinacea-group (P = 0.0004, P < 0.0001, P = 0.05, respectively). Up to day 70 of age, the rate of therapeutical treatments of piglets from echinacea-treated sows was decreased in tendency (P = 0.08). The growth performance and carcass quality of offspring was not influenced by echinacea treatment of sows.

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