scholarly journals Bone Marrow Ablation

2020 ◽  
Author(s):  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Ablation ◽  
Marrow Ablation

Human serum and plasma have different sources of epidermal growth factor

1990 ◽  
Vol 259 (3) ◽  
pp. R545-R548 ◽  
Author(s):  
A. Lev-Ran ◽  
D. L. Hwang ◽  
D. S. Snyder
Keyword(s):  
Bone Marrow ◽  
Platelet Count ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Molecular Mass ◽  
High Performance ◽  
Regression Line ◽  
Bone Marrow Ablation ◽  
Epidermal Growth ◽  
Marrow Ablation

Epidermal growth factor (EGF) was determined by radioimmunoassay in serum, plasma, and urine of 23 patients undergoing ablative therapy followed by bone marrow transplantation. The difference between the serum and plasma values reflected the amount of EGF released from the platelets at the time of blood coagulation. Platelet-derived EGF strongly correlated with platelet count (r + 0.850, P less than 0.0001), and the intercept of the regression line was very close to zero; one platelet contained approximately 2.5 x 10(-18) g EGF. Correspondingly, when the platelet count dropped after bone marrow ablation from 222 +/- 97 to 33 +/- 13 x 10(9)/l, the serum EGF decreased from 603 +/- 222 to 65 +/- 41 pg/ml (P less than 0.0001). Plasma EGF content did not correlate with the platelet count and did not change significantly after bone marrow ablation (before and after the ablation, correspondingly, 290 +/- 80 and 332 +/- 99 pg/ml, P = 0.194). High-performance liquid chromatographic fractionation of serum and plasma showed different molecular mass distribution of EGF-immunoreactive fractions. The main molecular mass components of the plasma EGF did not change after bone marrow ablation. Urine excretion remained unchanged (320 +/- 133 and 314 +/- 173 pmol EGF/mmol creatinine). We conclude that whereas platelets are the source of serum EGF, the origin of plasma EGF is different and the search of its origin is warranted.

153Sm-EDTMP and melphalan chemoradiotherapy regimen for bone marrow ablation prior to marrow transplantation

1992 ◽  
Vol 13 (1) ◽  
pp. 321-329 ◽  
Author(s):  
J. H. TURNER ◽  
P. G. CLARINGBOLD ◽  
J. D. BERGER ◽  
A. A. MARTINDALE ◽  
J. R. GLANCY
Keyword(s):  
Bone Marrow ◽  
Marrow Transplantation ◽  
Bone Marrow Ablation ◽  
Marrow Ablation

ED-71, a novel vitamin D analog, promotes bone formation and angiogenesis and inhibits bone resorption after bone marrow ablation

Bone ◽  
2007 ◽  
Vol 40 (2) ◽  
pp. 281-292 ◽  
Author(s):  
N. Okuda ◽  
S. Takeda ◽  
K. Shinomiya ◽  
T. Muneta ◽  
S. Itoh ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Vitamin D ◽  
Bone Resorption ◽  
Bone Formation ◽  
Vitamin D Analog ◽  
Bone Marrow Ablation ◽  
Marrow Ablation

Bone-Marrow Ablation and Allogeneic Marrow Transplantation in Acute Leukemia

1980 ◽  
Vol 302 (19) ◽  
pp. 1041-1046 ◽  
Author(s):  
Karl G. Blume ◽  
Ernest Beutler ◽  
Klaus J. Bross ◽  
Ram K. Chillar ◽  
Owen B. Ellington ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Leukemia ◽  
Marrow Transplantation ◽  
Allogeneic Marrow Transplantation ◽  
Bone Marrow Ablation ◽  
Marrow Ablation ◽  
Allogeneic Marrow
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