scholarly journals APPLICATIONS OF THE TERAHERTZ ATR SPECTROSCOPY TO PHARMACOLOGY

2021 ◽  
Vol 78 (4) ◽  
pp. 467-474
Author(s):  
Edward Pliński ◽  
Norbert Pałka ◽  
Stanisława Plińska
Keyword(s):  
Atr Spectroscopy

Laser ATR Spectroscopy of Solid Surfaces

1986 ◽  
Vol 14 (2) ◽  
pp. 82-97
Author(s):  
Kou KUROSAWA ◽  
Sukekatu USHIODA
Keyword(s):  
Solid Surfaces ◽  
Atr Spectroscopy

scholarly journals Direct evidence of gel–sol transition in cyclodextrin-based hydrogels as revealed by FTIR-ATR spectroscopy

Soft Matter ◽  
2014 ◽  
Vol 10 (13) ◽  
pp. 2320-2326 ◽  
Author(s):  
Vincenza Crupi ◽  
Domenico Majolino ◽  
Andrea Mele ◽  
Lucio Melone ◽  
Carlo Punta ◽  
...  
Keyword(s):  
Direct Evidence ◽  
Atr Spectroscopy

Fig seeds: Combined Approach of Lipochemical Assessment Using Gas Chromatography and FTIR-ATR Spectroscopy Using Chemometrics

2021 ◽  
pp. 103251
Author(s):  
Lahcen Hssaini ◽  
Rachid Razouk ◽  
Jamal Charafi ◽  
Karim Houmanat ◽  
Hafida Hanine
Keyword(s):  
Gas Chromatography ◽  
Combined Approach ◽  
Atr Spectroscopy

In Vitro Mineralization and Cell Adhesion on Surface Modified Poly (2 - hydroxy ethyl methacrylate-co-methyl methacrylate

2006 ◽  
Vol 309-311 ◽  
pp. 493-496 ◽  
Author(s):  
G.S. Sailaja ◽  
T.V. Kumari ◽  
Yoshiyuki Yokogawa ◽  
H.K. Varma
Keyword(s):  
Cell Adhesion ◽  
Calcium Phosphate ◽  
Methyl Methacrylate ◽  
Radical Copolymerization ◽  
Sem Analysis ◽  
Free Radical Copolymerization ◽  
In Vitro Mineralization ◽  
Atr Spectroscopy ◽  
Surface Modified

Poly(2-hydroxyethyl methacrylate-co- methyl methacrylate) HM, was synthesized by free radical copolymerization, cross-linked with ethylene glycol dimethacrylate and phosphorylated. The phosphate coupling was ensured by ATR spectroscopy. The in vitro mineralization ability of the phosphorylated HM (designated as PHM) was investigated by studying the nucleation and growth of calcium phosphate on its surface by immersing in simulated body fluid (SBF) solution. The coating morphology was studied by SEM and the Ca/P ratio of the coating by EDX analysis. The cell adhesion behaviour of PHM was studied by seeding Human osteosarcoma (HOS) cells for one week followed by SEM analysis along with HM as control. It was observed that HOS cells exhibited biomineralization of calcium phosphate on the surface of HM as well as on PHM with a significantly higher amount on the surface of PHM as observed by von kossa staining method. The results show that PHM is capable of in vitro mineralization under simulated physiological condition, promotes cell adhesion by providing an excellent cell friendly surface and it exhibits biomineralization of calcium phosphate in presence of HOS cells.

Diffusion Measurements Using FT-IR ATR Spectroscopy: Lubricant Diffusion in Polypropylene

2002 ◽  
Vol 56 (4) ◽  
pp. 509-514 ◽  
Author(s):  
Xiaohua Yi ◽  
Karen Nerbonne ◽  
John Pellegrino
Keyword(s):  
Current Model ◽  
Mineral Oil ◽  
Attenuated Total Reflection ◽  
Lubricant Layer ◽  
Polymer Interfaces ◽  
Time Resolved ◽  
Polymer Sample ◽  
Ft Ir ◽  
Atr Spectroscopy ◽  
Poly Propylene

We present an experimental method for measuring diffusion of lubricants (or any highly viscous fluid) in polymers using Fourier transform infrared (FT-IR) attenuated total reflection (ATR) spectroscopy. Unlike the conventional FT-IR ATR diffusion measurement, in which a polymer sample is sandwiched between the penetrant and an internal reflection element (IRE), in this method, a thin layer of penetrant (for example, a lubricant) is sandwiched between the IRE and the polymer sample. This allows accurate control and measurement of the thickness of the lubricant layer, which, in turn, facilitates subsequent data analysis. The diffusion is studied by monitoring the time-resolved change in absorbance of either a unique polymer or penetrant band. A feature of this new method is that it can provide an estimate of solubility, as well as an estimate of the diffusivity of the penetrant in the polymer. Using this method, we studied the diffusion of mineral oil and a commercial fluorocarbon ether lubricant (Krytox® 143AC‡) in poly(propylene) (PP) film at room temperature. The experimental data was modeled using a Fickian model with impermeable and saturated boundary conditions applied at the IRE/lubricant and lubricant/polymer interfaces, respectively. The diffusivity and solubility of mineral oil in PP were found to be 1.34 ± 0.35 (×10−10) cm2/s and 0.77 ± 0.13 (×10−2) g/g of PP, respectively. The current model was unable to quantitatively describe the diffusion of the Krytox® 143AC in the PP, possibly due to excessive swelling.

Model Optimization and Stability of Hemoglobin Analysis in Human Soluble Blood Samples by FTIR/ATR Spectroscopy

2011 ◽  
Vol 55-57 ◽  
pp. 1168-1171
Author(s):  
Tao Pan ◽  
Ai Hong Peng ◽  
Wen Jie Huang
Keyword(s):  
Signal To Noise Ratio ◽  
Attenuated Total Reflection ◽  
Partial Least Square ◽  
Least Square ◽  
Model Optimization ◽  
Optimal Model ◽  
Blood Samples ◽  
Quantification Method ◽  
Atr Spectroscopy ◽  
Pls Method

Using Fourier transform infrared spectroscopy (FTIR), attenuated total reflection (ATR) technology and partial least square (PLS) method, the rapid quantification method of hemoglobin (HGB) in human soluble blood samples was established. Based on the distribution of samples’ HGB chemical value and absorbance on 1543 cm-1 which had the highest signal to noise ratio for HGB, all samples were divided into calibration set and prediction set for 50 times. PLS models were established for all divisions, based on the average data RMSEPAve, the stable optimal model was selected, the corresponding PLS factor, RMSEPAve and RP,Ave were 2, 6.81 g/L and 0.943 respectively.

Application Of Systems With Total Internal Reflection At Novosibirsk Free Electron Laser For Spectroscopy In The Terahertz Range

2016 ◽  
Vol 11 (3) ◽  
pp. 72-82
Author(s):  
Vasily Gerasimov ◽  
Elvira Grigorieva ◽  
Boris Knyazev ◽  
Yuliya Choporova
Keyword(s):  
Free Electron ◽  
Free Electron Laser ◽  
Quantum Cascade Lasers ◽  
Attenuated Total Reflection ◽  
Terahertz Range ◽  
Optical Systems ◽  
Early Diagnosis Of Cancer ◽  
Infrared Spectral ◽  
Atr Spectroscopy ◽  
Spectral Ranges

Attenuated total reflection (ATR) spectroscopy is widely used in the visible and infrared spectral ranges. Progress in the development of laboratory scale monochromatic sources of terahertz radiation, such as quantum cascade lasers, suggests that in the near future this kind of spectrometers will be widely spread in the terahertz range. For this reason, the development of ATR based methods and devices is highly relevant. In this paper, we discuss the features of the use of ATR spectroscopy in the terahertz range, and describe some of the optical systems, designed for experiments at the Novosibirsk free electron laser (NovoFEL). We show that in the terahertz range the ATR spectroscopy has a number of significant advantages over the absorption spectroscopy. As an example, we are discussing the possibility of using terahertz polarimetry to develop a method for early diagnosis of cancer via the detection of left-handed to right-handed polysaccharide enantiomers ratio. Spectra of selected polysaccharides were recorded with a standard Fourier spectrometer using developed by us an ATR unit. The possibility of studying the polarization characteristics of polysaccharides in aqueous solutions using spectrally selective polarimeter with the NovoFEL as a tunable radiation source was demonstrated.

Sign in / Sign up

Export Citation Format

Share Document