scholarly journals Chromatographic Behaviour and Analytical Method Development for Metformin HCl: Application to Permeation Studies through Caco-2 Cells

2020 ◽  
Vol 77 (1) ◽  
pp. 11-21
Author(s):  
Imad Hamdan ◽  
Dua'a Farah ◽  
Rana Abu-Dahaba Abu-Dahab
Keyword(s):  
Analytical Method ◽  
Method Development ◽  
Chromatographic Behaviour ◽  
Permeation Studies ◽  
Metformin Hcl

scholarly journals Chiral analytical method development of liquiritigenin with application to a pharmacokinetic study

2012 ◽  
pp. n/a-n/a
Author(s):  
Casey L. Sayre ◽  
Mandi Hopkins ◽  
Jody K. Takemoto ◽  
Neal M. Davies
Keyword(s):  
Pharmacokinetic Study ◽  
Analytical Method ◽  
Method Development

Developments in mycotoxin analysis: an update for 2010-2011

2012 ◽  
Vol 5 (1) ◽  
pp. 3-30 ◽  
Author(s):  
G. Shephard ◽  
F. Berthiller ◽  
P. Burdaspal ◽  
C. Crews ◽  
M. Jonker ◽  
...  
Keyword(s):  
Analytical Method ◽  
Analytical Methods ◽  
Method Development ◽  
Rapid Development ◽  
Ergot Alkaloids ◽  
Alternaria Toxins ◽  
Research Publications ◽  
Mycotoxin Analysis ◽  
The Subject ◽  
Conventional Methods

This review highlights developments in mycotoxin analysis and sampling over a period between mid-2010 and mid-2011. It covers the major mycotoxins: aflatoxins, Alternaria toxins, ergot alkaloids, fumonisins, ochratoxin, patulin, trichothecenes, and zearalenone. Analytical methods for mycotoxins continue to be developed and published. Despite much interest in immunochemical methods and in the rapid development of LC-MS methodology, more conventional methods, sometimes linked to novel clean-up protocols, have also been the subject of research publications over the above period. Occurrence of mycotoxins falls outside the main focus of this review; however, where relevant to analytical method development, this has been mentioned.

A Review: Method Development Validation and Degradation Studies of some Anticancer Drugs

2021 ◽  
pp. 5443-5448
Author(s):  
Punna Venkateshwarlu ◽  
Mehul M. Patel
Keyword(s):  
Liquid Chromatography ◽  
Anticancer Drugs ◽  
Analytical Method ◽  
Analytical Methods ◽  
Bioanalytical Methods ◽  
Method Development ◽  
Estimation Methods ◽  
Simultaneous Estimation ◽  
Pharmaceutical Dosage Forms ◽  
Stability Indicating

This article reviews the various analytical methods reported so far in the literature for the determination of stability and impurity profile the lenalidomide and palbociclib anti cancer drugs in single or combination with other drugs in bulk, pharmaceutical dosage forms, biological fluids, stability indicating and impurity profiling methods. The analytical methods used for the estimation of lenalidomide and palbociclib anticancer drugs reviewed in this paper includes ultraviolet spectrophotometry,high performance liquid chromatography (HPLC) ,ultra performance liquid chromatography (UPLC) ,liquid chromatography-mass spectrometry (LC-MS) and electrophoresis. This review focus on the effect of all chromatographic parameters so as to provide as fast, reliable and cost effective methodology of testing. Method development is the process of proving that analytical method is acceptable for use to measure the concentration of active pharmaceutical ingredient in a specific compound dosage form which must be validated to provide reliable data for regulatory submissions. This reviewed is mainly on analytical method development and validation, stability indicating methods, simultaneous estimation methods and bioanalytical methods. The review covers the time period from 2007 to 2019 during which analytical methods including all types of spectrophotometric and chromatographic techniques were reported. The Review covers lenalidomide and palbociclib API and formulation analytical and bioanalytical methods.

Benzimidazoles in wastewater: Analytical method development, monitoring and degradation by photolysis and ozonation

2019 ◽  
Vol 232 ◽  
pp. 729-737 ◽  
Author(s):  
Rafael Silveira Porto ◽  
Caio Rodrigues-Silva ◽  
Jerusa Schneider ◽  
Susanne Rath
Keyword(s):  
Analytical Method ◽  
Method Development
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